Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7 AM Brown, JM Jeltsch, M Roberts, P Chambon Proceedings of the National Academy of Sciences 81 (20), 6344-6348, 1984 | 476 | 1984 |
Wnt signaling and breast cancer LR Howe, AMC Brown Cancer biology & therapy 3 (1), 36-41, 2004 | 454 | 2004 |
Wnt-1 regulation of connexin43 in cardiac myocytes Z Ai, A Fischer, DC Spray, AMC Brown, GI Fishman Journal of Clinical Investigation 105 (2), 161, 2000 | 449 | 2000 |
An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway FC Gonsalves, K Klein, BB Carson, S Katz, LA Ekas, S Evans, ... Proceedings of the National Academy of Sciences 108 (15), 5954-5963, 2011 | 389 | 2011 |
Wnt proteins in mammary development and cancer KR Brennan, AMC Brown Journal of mammary gland biology and neoplasia 9, 119-131, 2004 | 367 | 2004 |
The proto‐oncogene int‐1 encodes a secreted protein associated with the extracellular matrix. RS Bradley, AM Brown The EMBO Journal 9 (5), 1569-1575, 1990 | 365 | 1990 |
Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion. RS Bradley, P Cowin, AM Brown The Journal of Cell Biology 123 (6), 1857-1865, 1993 | 338 | 1993 |
Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation LR Howe, O Watanabe, J Leonard, AMC Brown Cancer research 63 (8), 1906-1913, 2003 | 314 | 2003 |
Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression M Kucherlapati, K Yang, M Kuraguchi, J Zhao, M Lia, J Heyer, MF Kane, ... Proceedings of the National Academy of Sciences 99 (15), 9924-9929, 2002 | 297 | 2002 |
Wnt signaling promotes oncogenic transformation by inhibiting c-Myc–induced apoptosis Z You, D Saims, S Chen, Z Zhang, DC Guttridge, K Guan, ... J Cell Biol 157 (3), 429-440, 2002 | 271 | 2002 |
Transcriptional Activation of Cyclooxygenase-2 in Wnt-1-transformed Mouse Mammary Epithelial Cells LR Howe, K Subbaramaiah, WJ Chung, AJ Dannenberg, AMC Brown Cancer Research 59 (7), 1572-1577, 1999 | 262 | 1999 |
Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancer LR Howe, K Subbaramaiah, J Patel, JL Masferrer, A Deora, C Hudis, ... Cancer research 62 (19), 5405-5407, 2002 | 259 | 2002 |
Wnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2 TNH Masckauchán, D Agalliu, M Vorontchikhina, A Ahn, NL Parmalee, ... Molecular biology of the cell 17 (12), 5163-5172, 2006 | 257 | 2006 |
Caveolin-1 expression inhibits Wnt/β-catenin/Lef-1 signaling by recruiting β-catenin to caveolae membrane domains F Galbiati, AMC Brown, DE Weinstein, A Ben-Ze'ev, RG Pestell, ... Journal of Biological Chemistry 275 (30), 23368-23377, 2000 | 257 | 2000 |
Wnt-5a and Wnt-7a are expressed in the developing chick limb bud in a manner suggesting roles in pattern formation along the proximodistal and dorsoventral axes CN Dealy, A Roth, D Ferrari, AMC Brown, RA Kosher Mechanisms of development 43 (2-3), 175-186, 1993 | 254 | 1993 |
A retrovirus vector expressing the putative mammary oncogene int-1 causes partial transformation of a mammary epithelial cell line AMC Brown, RS Wildin, TJ Prendergast, HE Varmus Cell 46 (7), 1001-1009, 1986 | 238 | 1986 |
Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice W Edelmann, K Yang, M Kuraguchi, J Heyer, M Lia, B Kneitz, K Fan, ... Cancer Research 59 (6), 1301-1307, 1999 | 234 | 1999 |
Inhibition of Chondrogenesis byWntGene Expressionin Vivoandin Vitro JA Rudnicki, AMC Brown Developmental biology 185 (1), 104-118, 1997 | 227 | 1997 |
Mbd4 inactivation increases C→ T transition mutations and promotes gastrointestinal tumor formation E Wong, K Yang, M Kuraguchi, U Werling, E Avdievich, K Fan, M Fazzari, ... Proceedings of the National Academy of Sciences 99 (23), 14937-14942, 2002 | 209 | 2002 |
Wnt signaling in breast cancer: have we come full circle? AMC Brown Breast Cancer Research 3, 1-5, 2001 | 206 | 2001 |