Pawel Buczkowicz
Pawel Buczkowicz
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K27M mutation in histone H3. 3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
DA Khuong-Quang, P Buczkowicz, P Rakopoulos, XY Liu, ...
Acta neuropathologica 124 (3), 439-447, 2012
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ...
Nature genetics 46 (5), 451-456, 2014
Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor α and poly (ADP-ribose) polymerase as potential …
M Zarghooni, U Bartels, E Lee, P Buczkowicz, A Morrison, A Huang, ...
Journal of clinical oncology 28 (8), 1337-1344, 2010
Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implications
P Buczkowicz, U Bartels, E Bouffet, O Becher, C Hawkins
Acta neuropathologica 128 (4), 573-581, 2014
BRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma
M Mistry, N Zhukova, D Merico, P Rakopoulos, R Krishnatry, M Shago, ...
Journal of clinical oncology 33 (9), 1015, 2015
Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics
LM Hoffman, M DeWire, S Ryall, P Buczkowicz, J Leach, L Miles, ...
Acta neuropathologica communications 4 (1), 1-8, 2016
Spatial heterogeneity in medulloblastoma
AS Morrissy, FMG Cavalli, M Remke, V Ramaswamy, DJH Shih, ...
Nature genetics 49 (5), 780-788, 2017
Targeted detection of genetic alterations reveal the prognostic impact of H3K27M and MAPK pathway aberrations in paediatric thalamic glioma
S Ryall, R Krishnatry, A Arnoldo, P Buczkowicz, M Mistry, R Siddaway, ...
Acta neuropathologica communications 4 (1), 93, 2016
Pathology, molecular genetics, and epigenetics of diffuse intrinsic pontine glioma
P Buczkowicz, C Hawkins
Frontiers in oncology 5, 147, 2015
ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents
S Agnihotri, K Burrell, P Buczkowicz, M Remke, B Golbourn, ...
Cancer discovery 4 (10), 1198-1213, 2014
Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors
J Mangerel, A Price, P Castelo-Branco, J Brzezinski, P Buczkowicz, ...
Acta neuropathologica 128 (6), 853-862, 2014
Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells
M Barszczyk, P Buczkowicz, P Castelo-Branco, SC Mack, V Ramaswamy, ...
Acta neuropathologica 128 (6), 863-877, 2014
A urora Kinase B Is a Potential Therapeutic Target in Pediatric Diffuse Intrinsic Pontine Glioma
P Buczkowicz, M Zarghooni, U Bartels, A Morrison, KL Misuraca, T Chan, ...
Brain pathology 23 (3), 244-253, 2013
GLI2 is a potential therapeutic target in pediatric medulloblastoma
P Buczkowicz, J Ma, C Hawkins
Journal of Neuropathology & Experimental Neurology 70 (6), 430-437, 2011
Poly-ADP-ribose polymerase as a therapeutic target in pediatric diffuse intrinsic pontine glioma and pediatric high-grade astrocytoma
Y Chornenkyy, S Agnihotri, M Yu, P Buczkowicz, P Rakopoulos, ...
Molecular cancer therapeutics 14 (11), 2560-2568, 2015
Identification of complex genomic rearrangements in cancers using CouGaR
M Dzamba, AK Ramani, P Buczkowicz, Y Jiang, M Yu, C Hawkins, ...
Genome research 27 (1), 107-117, 2017
Preclinical evaluation of convection-enhanced delivery of liposomal doxorubicin to treat pediatric diffuse intrinsic pontine glioma and thalamic high-grade glioma
ACP Sewing, T Lagerweij, DG van Vuurden, MH Meel, SJE Veringa, ...
Journal of Neurosurgery: Pediatrics 19 (5), 518-530, 2017
Abstract B12: H3-K27M is a negative prognostic marker in high-and low-grade pediatric thalamic glioma
S Ryall, P Buczkowicz, A Arnoldo, R Krishnatry, M Mistry, J Rubin, ...
Cancer Research 76 (2 Supplement), B12-B12, 2016
Comprehensive Integrated Genomic and Histopathological Analysis of Paediatric Diffuse Intrinsic Pontine Glioma
P Buczkowicz
The promising immune checkpoint LAG-3: from tumor microenvironment to cancer immunotherapy
A Charest, J Huse, M Khasraw, M Viapiano, K Aldape, DA Khuong-Quang, ...
Neuro-Oncology 22 (1), 13-16, 2020
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