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Pavel Uvarov
Pavel Uvarov
Haartman Institute, University of Helsinki
E-mail confirmado em helsinki.fi
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Current view on the functional regulation of the neuronal K+-Cl cotransporter KCC2
I Medina, P Friedel, C Rivera, KT Kahle, N Kourdougli, P Uvarov, ...
Frontiers in cellular neuroscience 8, 27, 2014
2062014
A novel N-terminal isoform of the neuron-specific K-Cl cotransporter KCC2
P Uvarov, A Ludwig, M Markkanen, P Pruunsild, K Kaila, E Delpire, ...
Journal of Biological Chemistry 282 (42), 30570-30576, 2007
1802007
Early growth response 4 mediates BDNF induction of potassium chloride cotransporter 2 transcription
A Ludwig, P Uvarov, S Soni, J Thomas-Crusells, MS Airaksinen, C Rivera
Journal of Neuroscience 31 (2), 644-649, 2011
1252011
Coexpression and heteromerization of two neuronal K-Cl cotransporter isoforms in neonatal brain
P Uvarov, A Ludwig, M Markkanen, S Soni, CA Hubner, C Rivera, ...
Journal of Biological Chemistry 284 (20), 13696-13704, 2009
1002009
Upregulation of the neuron-specific K+/Cl− cotransporter expression by transcription factor early growth response 4
P Uvarov, A Ludwig, M Markkanen, C Rivera, MS Airaksinen
Journal of Neuroscience 26 (52), 13463-13473, 2006
922006
Kainate receptors coexist in a functional complex with KCC2 and regulate chloride homeostasis in hippocampal neurons
V Mahadevan, JC Pressey, BA Acton, P Uvarov, MY Huang, J Chevrier, ...
Cell reports 7 (6), 1762-1770, 2014
842014
LRRTM3 regulates excitatory synapse development through alternative splicing and neurexin binding
JW Um, TY Choi, H Kang, YS Cho, G Choii, P Uvarov, D Park, D Jeong, ...
Cell reports 14 (4), 808-822, 2016
712016
Hyperpolarizing GABAergic transmission requires the KCC2 C-terminal ISO domain
BA Acton, V Mahadevan, A Mercado, P Uvarov, Y Ding, J Pressey, ...
Journal of Neuroscience 32 (25), 8746-8751, 2012
662012
The multifaceted roles of KCC2 in cortical development
MA Virtanen, P Uvarov, M Mavrovic, JC Poncer, K Kaila
Trends in neurosciences 44 (5), 378-392, 2021
642021
Distribution of neuronal KCC2a and KCC2b isoforms in mouse CNS
M Markkanen, T Karhunen, O Llano, A Ludwig, C Rivera, P Uvarov, ...
Journal of Comparative Neurology 522 (8), 1897-1914, 2014
602014
Vasopressin excites interneurons to suppress hippocampal network activity across a broad span of brain maturity at birth
A Spoljaric, P Seja, I Spoljaric, MA Virtanen, J Lindfors, P Uvarov, ...
Proceedings of the National Academy of Sciences 114 (50), E10819-E10828, 2017
582017
Native KCC2 interactome reveals PACSIN1 as a critical regulator of synaptic inhibition
V Mahadevan, CS Khademullah, Z Dargaei, J Chevrier, P Uvarov, J Kwan, ...
Elife 6, e28270, 2017
562017
Neuronal K+/Cl co‐transporter (KCC2) transgenes lacking neurone restrictive silencer element recapitulate CNS neurone‐specific expression and developmental up …
P Uvarov, P Pruunsild, T Timmusk, MS Airaksinen
Journal of neurochemistry 95 (4), 1144-1155, 2005
562005
Neurturin evokes MAPK-dependent upregulation of Egr4 and KCC2 in developing neurons
A Ludwig, P Uvarov, C Pellegrino, J Thomas-Crusells, S Schuchmann, ...
Neural plasticity 2011, 2011
502011
NKCC1, an elusive molecular target in brain development: making sense of the existing data
MA Virtanen, P Uvarov, CA Hübner, K Kaila
Cells 9 (12), 2607, 2020
492020
A kainate receptor subunit promotes the recycling of the neuron-specific K+-Cl− co-transporter KCC2 in hippocampal neurons
JC Pressey, V Mahadevan, CS Khademullah, Z Dargaei, J Chevrier, W Ye, ...
Journal of Biological Chemistry 292 (15), 6190-6201, 2017
392017
Role of upstream stimulating factors in the transcriptional regulation of the neuron-specific K–Cl cotransporter KCC2
M Markkanen, P Uvarov, MS Airaksinen
Brain research 1236, 8-15, 2008
362008
Up-and down-regulation of Helix command-specific 2 (HCS2) gene expression in the nervous system of terrestrial snail Helix lucorum
PM Balaban, DA Poteryaev, IS Zakharov, P Uvarov, A Malyshev, ...
Neuroscience 103 (2), 551-559, 2001
312001
Implications of the N-terminal heterogeneity for the neuronal K-Cl cotransporter KCC2 function
M Markkanen, A Ludwig, S Khirug, E Pryazhnikov, S Soni, L Khiroug, ...
Brain research 1675, 87-101, 2017
292017
Role of the K+-Cl–Cotransporter KCC2a Isoform in Mammalian Respiration at Birth
CJ Dubois, L Cardoit, V Schwarz, M Markkanen, MS Airaksinen, P Uvarov, ...
ENeuro 5 (5), 2018
182018
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