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Danwei Huangfu
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Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
D Huangfu, R Maehr, W Guo, A Eijkelenboom, M Snitow, AE Chen, ...
Nature biotechnology 26 (7), 795-797, 2008
21442008
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
D Huangfu, K Osafune, R Maehr, W Guo, A Eijkelenboom, S Chen, ...
Nature biotechnology 26 (11), 1269-1275, 2008
18902008
Hedgehog signalling in the mouse requires intraflagellar transport proteins
D Huangfu, A Liu, AS Rakeman, NS Murcia, L Niswander, KV Anderson
Nature 426 (6962), 83-87, 2003
15752003
A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog
JK Ichida, J Blanchard, K Lam, EY Son, JE Chung, D Egli, KM Loh, ...
Cell stem cell 5 (5), 491-503, 2009
9542009
Cilia and Hedgehog responsiveness in the mouse
D Huangfu, KV Anderson
Proceedings of the National Academy of Sciences 102 (32), 11325-11330, 2005
9272005
Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates
D Huangfu, KV Anderson
Oxford University Press for The Company of Biologists Limited 133 (1), 3-14, 2006
6162006
An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells
F González, Z Zhu, ZD Shi, K Lelli, N Verma, QV Li, D Huangfu
Cell stem cell 15 (2), 215-226, 2014
5242014
All β cells contribute equally to islet growth and maintenance
K Brennand, D Huangfu, D Melton
PLoS biology 5 (7), e163, 2007
2692007
CRISPR/Cas9-based engineering of the epigenome
J Pulecio, N Verma, E Mejía-Ramírez, D Huangfu, A Raya
Cell stem cell 21 (4), 431-447, 2017
2632017
Human pluripotent stem cells: an emerging model in developmental biology
Z Zhu, D Huangfu
Development 140 (4), 705-717, 2013
2392013
Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling
T Caspary, MJ Garcıa-Garcıa, D Huangfu, JT Eggenschwiler, MR Wyler, ...
Current biology 12 (18), 1628-1632, 2002
2212002
Genome editing of lineage determinants in human pluripotent stem cells reveals mechanisms of pancreatic development and diabetes
Z Zhu, QV Li, K Lee, BP Rosen, F González, CL Soh, D Huangfu
Cell stem cell 18 (6), 755-768, 2016
1802016
TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells
N Verma, H Pan, LC Doré, A Shukla, QV Li, B Pelham-Webb, V Teijeiro, ...
Nature genetics 50 (1), 83-95, 2018
1712018
Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells
AG Kotini, CJ Chang, I Boussaad, JJ Delrow, EK Dolezal, AB Nagulapally, ...
Nature biotechnology 33 (6), 646-655, 2015
1592015
Genome editing in hPSCs reveals GATA6 haploinsufficiency and a genetic interaction with GATA4 in human pancreatic development
ZD Shi, K Lee, D Yang, S Amin, N Verma, QV Li, Z Zhu, CL Soh, R Kumar, ...
Cell stem cell 20 (5), 675-688. e6, 2017
1552017
Analysis of mouse embryonic patterning and morphogenesis by forward genetics
MJ García-García, JT Eggenschwiler, T Caspary, HL Alcorn, MR Wyler, ...
Proceedings of the National Academy of Sciences 102 (17), 5913-5919, 2005
1522005
The p53 family coordinates Wnt and nodal inputs in mesendodermal differentiation of embryonic stem cells
Q Wang, Y Zou, S Nowotschin, SY Kim, QV Li, CL Soh, J Su, C Zhang, ...
Cell Stem Cell 20 (1), 70-86, 2017
1502017
FOXA2 is required for enhancer priming during pancreatic differentiation
K Lee, H Cho, RW Rickert, QV Li, J Pulecio, CS Leslie, D Huangfu
Cell reports 28 (2), 382-393. e7, 2019
1172019
A CRISPR/Cas-mediated selection-free knockin strategy in human embryonic stem cells
Z Zhu, N Verma, F González, ZD Shi, D Huangfu
Stem cell reports 4 (6), 1103-1111, 2015
1012015
Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation
QV Li, G Dixon, N Verma, BP Rosen, M Gordillo, R Luo, C Xu, Q Wang, ...
Nature genetics 51 (6), 999-1010, 2019
992019
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