| Protein kinase C contains a pseudosubstrate prototope in its regulatory domain C House, BE Kemp Science 238 (4834), 1726-1728, 1987 | 1313 | 1987 |
| Mammalian AMP-activated protein kinase subfamily (∗) D Stapleton, KI Mitchelhill, G Gao, J Widmer, BJ Michell, T Teh, CM House, ... Journal of Biological Chemistry 271 (2), 611-614, 1996 | 822 | 1996 |
| Mammalian AMP-activated protein kinase shares structural and functional homology with the catalytic domain of yeast Snf1 protein kinase. KI Mitchelhill, D Stapleton, G Gao, C House, B Michell, F Katsis, LA Witters, ... Journal of Biological Chemistry 269 (4), 2361-2364, 1994 | 415 | 1994 |
| The influence of basic residues on the substrate specificity of protein kinase C. C House, RE Wettenhall, BE Kemp Journal of Biological Chemistry 262 (2), 772-777, 1987 | 311 | 1987 |
| Structural basis of autoregulation of phenylalanine hydroxylase B Kobe, IG Jennings, CM House, BJ Michell, KE Goodwill, BD Santarsiero, ... Nature structural biology 6 (5), 442-448, 1999 | 298 | 1999 |
| Inhibiting the system xC−/glutathione axis selectively targets cancers with mutant-p53 accumulation DS Liu, CP Duong, S Haupt, KG Montgomery, CM House, WJ Azar, ... Nature communications 8 (1), 14844, 2017 | 284 | 2017 |
| IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer MS Anglesio, J George, H Kulbe, M Friedlander, D Rischin, C Lemech, ... Clinical cancer research 17 (8), 2538-2548, 2011 | 264 | 2011 |
| Deregulation of MYCN, LIN28B and LET7 in a Molecular Subtype of Aggressive High-Grade Serous Ovarian Cancers Å Helland, MS Anglesio, J George, PA Cowin, CN Johnstone, CM House, ... PloS one 6 (4), e18064, 2011 | 218 | 2011 |
| Posttranslational modifications of the 5′-AMP-activated protein kinase β1 subunit KI Mitchelhill, BJ Michell, CM House, D Stapleton, J Dyck, J Gamble, ... Journal of Biological Chemistry 272 (39), 24475-24479, 1997 | 196 | 1997 |
| Mutagenesis of the pseudosubstrate site of protein kinase C leads to activation CJ Pears, G Kour, C HOUSE, BE Kemp, PJ Parker European journal of biochemistry 194 (1), 89-94, 1990 | 196 | 1990 |
| Substrate and pseudosubstrate interactions with protein kinases: determinants of specificity BE Kemp, MW Parker, S Hu, T Tiganis, C House Trends in biochemical sciences 19 (11), 440-444, 1994 | 179 | 1994 |
| Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-α signaling G Polekhina, CM House, N Traficante, JP Mackay, F Relaix, DA Sassoon, ... Nature structural biology 9 (1), 68-75, 2002 | 165 | 2002 |
| A binding motif for Siah ubiquitin ligase CM House, IJ Frew, HL Huang, G Wiche, N Traficante, E Nice, B Catimel, ... Proceedings of the National Academy of Sciences 100 (6), 3101-3106, 2003 | 160 | 2003 |
| Mammalian 5'-AMP-activated protein kinase non-catalytic subunits are homologs of proteins that interact with yeast Snf1 protein kinase. D Stapleton, G Gao, BJ Michell, J Widmer, K Mitchelhill, T Teh, CM House, ... Journal of biological chemistry 269 (47), 29343-29346, 1994 | 155 | 1994 |
| [24] Pseudosubstrate-based peptide inhibitors BE Kemp, RB Pearson, CM House Methods in enzymology 201, 287-304, 1991 | 148 | 1991 |
| Click chemistry enables preclinical evaluation of targeted epigenetic therapies DS Tyler, J Vappiani, T Cañeque, EYN Lam, A Ward, O Gilan, YC Chan, ... Science 356 (6345), 1397-1401, 2017 | 131 | 2017 |
| The ubiquitin ligase component Siah1a is required for completion of meiosis I in male mice RA Dickins, IJ Frew, CM House, MK O'Bryan, AJ Holloway, I Haviv, ... Molecular and cellular biology 22 (7), 2294-2303, 2002 | 123 | 2002 |
| Siah proteins: novel drug targets in the Ras and hypoxia pathways CM House, A Möller, DDL Bowtell Cancer research 69 (23), 8835-8838, 2009 | 121 | 2009 |
| Isoform-specific purification and substrate specificity of the 5′-AMP-activated protein kinase BJ Michell, D Stapleton, KI Mitchelhill, CM House, F Katsis, LA Witters, ... Journal of Biological Chemistry 271 (45), 28445-28450, 1996 | 117 | 1996 |
| Role of basic residues in the phosphorylation of synthetic peptides by myosin light chain kinase. BE Kemp, RB Pearson, C House Proceedings of the National Academy of Sciences 80 (24), 7471-7475, 1983 | 117 | 1983 |
