The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation G Leprivier, M Remke, B Rotblat, A Dubuc, ARF Mateo, M Kool, ... Cell 153 (5), 1064-1079, 2013 | 456 | 2013 |
Phosphatidic acid is a pH biosensor that links membrane biogenesis to metabolism BP Young, JJH Shin, R Orij, JT Chao, SC Li, XL Guan, A Khong, E Jan, ... Science 329 (5995), 1085-1088, 2010 | 331 | 2010 |
An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2α phosphorylation YY Lee, RC Cevallos, E Jan Journal of Biological Chemistry 284 (11), 6661-6673, 2009 | 325 | 2009 |
Factorless ribosome assembly on the internal ribosome entry site of cricket paralysis virus E Jan, P Sarnow Journal of molecular biology 324 (5), 889-902, 2002 | 324 | 2002 |
Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNA-based translation factor CMT Spahn, E Jan, A Mulder, RA Grassucci, P Sarnow, J Frank Cell 118 (4), 465-475, 2004 | 312 | 2004 |
The STAR protein, GLD‐1, is a translational regulator of sexual identity in Caenorhabditis elegans E Jan, CK Motzny, LE Graves, EB Goodwin The EMBO Journal, 1999 | 307 | 1999 |
The Imd pathway is involved in antiviral immune responses in Drosophila A Costa, E Jan, P Sarnow, D Schneider PloS one 4 (10), e7436, 2009 | 290 | 2009 |
Biosynthetic labeling of RNA with uracil phosphoribosyltransferase allows cell-specific microarray analysis of mRNA synthesis and decay MD Cleary, CD Meiering, E Jan, R Guymon, JC Boothroyd Nature biotechnology 23 (2), 232-237, 2005 | 228 | 2005 |
Divergent tRNA-like element supports initiation, elongation, and termination of protein biosynthesis E Jan, TG Kinzy, P Sarnow Proceedings of the National Academy of Sciences 100 (26), 15410-15415, 2003 | 156 | 2003 |
A cap-to-tail guide to mRNA translation strategies in virus-infected cells E Jan, I Mohr, D Walsh Annual review of virology 3 (1), 283-307, 2016 | 146 | 2016 |
Stress-mediated translational control in cancer cells G Leprivier, B Rotblat, D Khan, E Jan, PH Sorensen Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1849 (7), 845-860, 2015 | 138 | 2015 |
Divergent IRES elements in invertebrates E Jan Virus research 119 (1), 16-28, 2006 | 135 | 2006 |
Cleavage of sequestosome 1/p62 by an enteroviral protease results in disrupted selective autophagy and impaired NFKB signaling J Shi, J Wong, P Piesik, G Fung, J Zhang, J Jagdeo, X Li, E Jan, H Luo Autophagy 9 (10), 1591-1603, 2013 | 133 | 2013 |
ABC50 promotes translation initiation in mammalian cells S Paytubi, X Wang, YW Lam, L Izquierdo, MJ Hunter, E Jan, HS Hundal, ... Journal of Biological Chemistry 284 (36), 24061-24073, 2009 | 129 | 2009 |
The STAR protein QKI-6 is a translational repressor L Saccomanno, C Loushin, E Jan, E Punkay, K Artzt, EB Goodwin Proceedings of the National Academy of Sciences 96 (22), 12605-12610, 1999 | 125 | 1999 |
Initiation factor-independent translation mediated by the hepatitis C virus internal ribosome entry site AM Lancaster, E Jan, P Sarnow Rna 12 (5), 894-902, 2006 | 120 | 2006 |
mTOR signaling regulates the processing of pre-rRNA in human cells V Iadevaia, Z Zhang, E Jan, CG Proud Nucleic acids research 40 (6), 2527-2539, 2012 | 115 | 2012 |
Production of a dominant-negative fragment due to G3BP1 cleavage contributes to the disruption of mitochondria-associated protective stress granules during CVB3 infection G Fung, CS Ng, J Zhang, J Shi, J Wong, P Piesik, L Han, F Chu, J Jagdeo, ... PloS one 8 (11), e79546, 2013 | 109 | 2013 |
Induction of bleb structures in lipid nanoparticle formulations of mRNA leads to improved transfection potency MHY Cheng, J Leung, Y Zhang, C Strong, G Basha, A Momeni, Y Chen, ... Advanced Materials 35 (31), 2303370, 2023 | 97 | 2023 |
Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome I Pablos, Y Machado, HCR de Jesus, Y Mohamud, R Kappelhoff, ... Cell reports 37 (4), 2021 | 95 | 2021 |