| IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion V Gocheva, HW Wang, BB Gadea, T Shree, KE Hunter, AL Garfall, ... Genes & development 24 (3), 241-255, 2010 | 863 | 2010 |
| Distinct roles for cysteine cathepsin genes in multistage tumorigenesis V Gocheva, W Zeng, D Ke, D Klimstra, T Reinheckel, C Peters, ... Genes & development 20 (5), 543-556, 2006 | 636 | 2006 |
| Cysteine cathepsins and the cutting edge of cancer invasion V Gocheva, JA Joyce Cell cycle 6 (1), 60-64, 2007 | 529 | 2007 |
| VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation SH Chang, K Kanasaki, V Gocheva, G Blum, J Harper, MA Moses, ... Cancer research 69 (10), 4537-4544, 2009 | 152 | 2009 |
| Stromal expression of miR-143/145 promotes neoangiogenesis in lung cancer development N Dimitrova, V Gocheva, A Bhutkar, R Resnick, RM Jong, KM Miller, ... Cancer discovery 6 (2), 188-201, 2016 | 145 | 2016 |
| Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma TL Dayton, V Gocheva, KM Miller, WJ Israelsen, A Bhutkar, CB Clish, ... Genes & development 30 (9), 1020-1033, 2016 | 137 | 2016 |
| Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival V Gocheva, A Naba, A Bhutkar, T Guardia, KM Miller, CMC Li, TL Dayton, ... Proceedings of the National Academy of Sciences 114 (28), E5625-E5634, 2017 | 132 | 2017 |
| Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development SM Pyonteck, BB Gadea, HW Wang, V Gocheva, KE Hunter, LH Tang, ... Oncogene 31 (11), 1459-1467, 2012 | 131 | 2012 |
| Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix L Akkari, V Gocheva, JC Kester, KE Hunter, ML Quick, L Sevenich, ... Genes & development 28 (19), 2134-2150, 2014 | 120 | 2014 |
| Proteomic identification of cysteine cathepsin substrates shed from the surface of cancer cells B Sobotič, M Vizovišek, R Vidmar, P Van Damme, V Gocheva, JA Joyce, ... Molecular & Cellular Proteomics 14 (8), 2213-2228, 2015 | 103 | 2015 |
| Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis CMC Li, V Gocheva, MJ Oudin, A Bhutkar, SY Wang, SR Date, SR Ng, ... Genes & development 29 (17), 1850-1862, 2015 | 98 | 2015 |
| Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer V Gocheva, X Chen, C Peters, T Reinheckel, JA Joyce Walter de Gruyter 391 (8), 937-945, 2010 | 90 | 2010 |
| Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants LS Jacobson, H Lima, MF Goldberg, V Gocheva, V Tsiperson, ... Journal of Biological Chemistry 288 (11), 7481-7491, 2013 | 89 | 2013 |
| Design, synthesis, and evaluation of in vivo potency and selectivity of epoxysuccinyl-based inhibitors of papain-family cysteine proteases AM Sadaghiani, SHL Verhelst, V Gocheva, K Hill, E Majerova, S Stinson, ... Chemistry & biology 14 (5), 499-511, 2007 | 89 | 2007 |
| TAILS N-terminomics and proteomics show protein degradation dominates over proteolytic processing by cathepsins in pancreatic tumors A Prudova, V Gocheva, U auf dem Keller, U Eckhard, OC Olson, L Akkari, ... Cell reports 16 (6), 1762-1773, 2016 | 75 | 2016 |
| Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma AN Lau, Z Li, LV Danai, AM Westermark, AM Darnell, R Ferreira, ... Elife 9, e56782, 2020 | 69 | 2020 |
| Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model BT Elie, V Gocheva, T Shree, SA Dalrymple, LJ Holsinger, JA Joyce Biochimie 92 (11), 1618-1624, 2010 | 67 | 2010 |
| Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers MD Muzumdar, KJ Dorans, KM Chung, R Robbins, T Tammela, ... Nature communications 7 (1), 12685, 2016 | 63 | 2016 |
| Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer L Akkari, V Gocheva, ML Quick, JC Kester, AK Spencer, AL Garfall, ... Genes & development 30 (2), 220-232, 2016 | 61 | 2016 |
| Tumors: wounds that do not heal—a historical perspective with a focus on the fundamental roles of increased vascular permeability and clotting HF Dvorak Seminars in thrombosis and hemostasis 45 (06), 576-592, 2019 | 53 | 2019 |
