Gianni M. Castiglione
Gianni M. Castiglione
Postdoctoral Fellow, Johns Hopkins University School of Medicine
Verified email at
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ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection
L Zhou, Z Xu, GM Castiglione, US Soiberman, CG Eberhart, EJ Duh
The ocular surface 18 (4), 537-544, 2020
Accelerated evolution and functional divergence of the dim light visual pigment accompanies cichlid colonization of Central America
FE Hauser, KL Ilves, RK Schott, GM Castiglione, H López-Fernández, ...
Molecular Biology and Evolution 34 (10), 2650-2664, 2017
Evolution of nonspectral rhodopsin function at high altitudes
GM Castiglione, FE Hauser, BS Liao, NK Lujan, A Van Nynatten, ...
Proceedings of the National Academy of Sciences 114 (28), 7385-7390, 2017
Convergent selection pressures drive the evolution of rhodopsin kinetics at high altitudes via nonparallel mechanisms
GM Castiglione, RK Schott, FE Hauser, BSW Chang
Evolution 72 (1), 170-186, 2018
An experimental comparison of human and bovine rhodopsin provides insight into the molecular basis of retinal disease
JM Morrow, GM Castiglione, SZ Dungan, PL Tang, N Bhattacharyya, ...
FEBS letters 591 (12), 1720-1731, 2017
Functional shifts in bat dim-light visual pigment are associated with differing echolocation abilities and reveal molecular adaptation to photic-limited environments
EA Gutierrez, GM Castiglione, JM Morrow, RK Schott, LO Loureiro, ...
Molecular biology and evolution 35 (10), 2422-2434, 2018
Isolation and molecular characterization of the shikimate dehydrogenase domain from the Toxoplasma gondii AROM complex
J Peek, G Castiglione, T Shi, D Christendat
Molecular and biochemical parasitology 194 (1-2), 16-19, 2014
Functional trade-offs and environmental variation shaped ancient trajectories in the evolution of dim-light vision
GM Castiglione, BSW Chang
eLife 7, e35957, 2018
Comparative sequence analyses of rhodopsin and RPE65 reveal patterns of selective constraint across hereditary retinal disease mutations
FE Hauser, RK Schott, GM Castiglione, A Van Nynatten, A Kosyakov, ...
Visual neuroscience 33, 2016
Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds
GM Castiglione, Z Xu, L Zhou, EJ Duh
Nature Communications 11 (1), 1-15, 2020
Recreated ancestral opsin associated with marine to freshwater croaker invasion reveals kinetic and spectral adaptation
A Van Nynatten, GM Castiglione, E de A Gutierrez, NR Lovejoy, ...
Molecular Biology and Evolution, 2021
The ancient cardioprotective mechanisms of ACE2 bestow SARS-CoV-2 with a wide host range
GM Castiglione, L Zhou, Z Xu, Z Neiman, CF Hung, EJ Duh
bioRxiv, 2021.01. 03.425115, 2021
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