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David Brown
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High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants
P Razavi, BT Li, DN Brown, B Jung, E Hubbell, R Shen, W Abida, K Juluru, ...
Nature medicine 25 (12), 1928-1937, 2019
5412019
Loss of the FAT1 tumor suppressor promotes resistance to CDK4/6 inhibitors via the Hippo pathway
Z Li, P Razavi, Q Li, W Toy, B Liu, C Ping, W Hsieh, F Sanchez-Vega, ...
Cancer cell 34 (6), 893-905. e8, 2018
3642018
Genomic characterization of primary invasive lobular breast cancer
C Desmedt, G Zoppoli, G Gundem, G Pruneri, D Larsimont, M Fornili, ...
Journal of clinical oncology 34 (16), 1872-1881, 2016
3062016
Principles governing A-to-I RNA editing in the breast cancer transcriptome
D Fumagalli, D Gacquer, F Rothé, A Lefort, F Libert, D Brown, ...
Cell reports 13 (2), 277-289, 2015
2042015
Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations
D Brown, D Smeets, B Székely, D Larsimont, AM Szász, PY Adnet, ...
Nature communications 8 (1), 14944, 2017
1682017
Ultra-deep next-generation sequencing of plasma cell-free DNA in patients with advanced lung cancers: results from the Actionable Genome Consortium
BT Li, F Janku, B Jung, C Hou, K Madwani, R Alden, P Razavi, ...
Annals of oncology 30 (4), 597-603, 2019
1382019
Squalene epoxidase is a bona fide oncogene by amplification with clinical relevance in breast cancer
DN Brown, I Caffa, G Cirmena, D Piras, A Garuti, M Gallo, S Alberti, ...
Scientific reports 6 (1), 19435, 2016
1322016
Precision radiotherapy: reduction in radiation for oropharyngeal cancer in the 30 ROC trial
N Riaz, E Sherman, X Pei, H Schöder, M Grkovski, R Paudyal, N Katabi, ...
JNCI: Journal of the national cancer institute 113 (6), 742-751, 2021
1202021
Alterations in PTEN and ESR1 promote clinical resistance to alpelisib plus aromatase inhibitors
P Razavi, MN Dickler, PD Shah, W Toy, DN Brown, HH Won, BT Li, ...
Nature cancer 1 (4), 382-393, 2020
1142020
Immune infiltration in invasive lobular breast cancer
C Desmedt, R Salgado, M Fornili, G Pruneri, G Van den Eynden, ...
JNCI: Journal of the national cancer institute 110 (7), 768-776, 2018
1092018
Loss-of-function mutations in ATP6AP1 and ATP6AP2 in granular cell tumors
F Pareja, AH Brandes, T Basili, P Selenica, FC Geyer, D Fan, ...
Nature communications 9 (1), 3533, 2018
1072018
Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS
A Rose Brannon, G Jayakumaran, M Diosdado, J Patel, A Razumova, ...
Nature communications 12 (1), 3770, 2021
96*2021
Uncovering the genomic heterogeneity of multifocal breast cancer
C Desmedt, D Fumagalli, E Pietri, G Zoppoli, D Brown, S Nik‐Zainal, ...
The Journal of pathology 236 (4), 457-466, 2015
842015
HER2-overexpressing breast cancers amplify FGFR signaling upon acquisition of resistance to dual therapeutic blockade of HER2
AB Hanker, JT Garrett, MV Estrada, PD Moore, PG Ericsson, JP Koch, ...
Clinical cancer research 23 (15), 4323-4334, 2017
812017
Transfer of clinically relevant gene expression signatures in breast cancer: from Affymetrix microarray to Illumina RNA-Sequencing technology
D Fumagalli, A Blanchet-Cohen, D Brown, C Desmedt, D Gacquer, ...
BMC genomics 15, 1-12, 2014
812014
The genomic landscape of mucinous breast cancer
F Pareja, JY Lee, DN Brown, S Piscuoglio, R Gularte-Mérida, P Selenica, ...
JNCI: Journal of the national cancer institute 111 (7), 737-741, 2019
772019
Activation of the IFN signaling pathway is associated with resistance to CDK4/6 inhibitors and immune checkpoint activation in ER-positive breast cancer
C De Angelis, X Fu, ML Cataldo, A Nardone, R Pereira, J Veeraraghavan, ...
Clinical cancer research 27 (17), 4870-4882, 2021
63*2021
Tumor infiltrating lymphocytes (TILs) indicate trastuzumab benefit in early-stage HER2-positive breast cancer (HER2+ BC)
S Loi, S Michiels, R Salgado, N Sirtaine, V Jose, D Fumagalli, DN Brown, ...
Cancer research 73 (24 Supplement), S1-05-S1-05, 2013
61*2013
Somatic mutation, copy number and transcriptomic profiles of primary and matched metastatic estrogen receptor-positive breast cancers
D Fumagalli, TR Wilson, R Salgado, X Lu, J Yu, C O'Brien, K Walter, ...
Annals of oncology 27 (10), 1860-1866, 2016
572016
Whole-exome sequencing analysis of the progression from non–low-grade ductal carcinoma in situ to invasive ductal carcinoma
F Pareja, DN Brown, JY Lee, A Da Cruz Paula, P Selenica, R Bi, ...
Clinical cancer research 26 (14), 3682-3693, 2020
532020
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