| Requirement for CD4 T cell help in generating functional CD8 T cell memory DJ Shedlock, H Shen Science 300 (5617), 337-339, 2003 | 1945 | 2003 |
| Cutting edge: CD4 and CD8 T cells are intrinsically different in their proliferative responses KE Foulds, LA Zenewicz, DJ Shedlock, J Jiang, AE Troy, H Shen The Journal of Immunology 168 (4), 1528-1532, 2002 | 503 | 2002 |
| DNA vaccination: antigen presentation and the induction of immunity DJ Shedlock, DB Weiner Journal of leukocyte biology 68 (6), 793-806, 2000 | 358 | 2000 |
| Chikungunya: a potentially emerging epidemic? MM Thiboutot, S Kannan, OU Kawalekar, DJ Shedlock, AS Khan, ... PLoS neglected tropical diseases 4 (4), e623, 2010 | 306 | 2010 |
| Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs NJ Sullivan, TW Geisbert, JB Geisbert, DJ Shedlock, L Xu, L Lamoreaux, ... PLoS medicine 3 (6), e177, 2006 | 261 | 2006 |
| Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection DJ Shedlock, JK Whitmire, J Tan, AS MacDonald, R Ahmed, H Shen The Journal of Immunology 170 (4), 2053-2063, 2003 | 234 | 2003 |
| A DNA vaccine against chikungunya virus is protective in mice and induces neutralizing antibodies in mice and nonhuman primates K Mallilankaraman, DJ Shedlock, H Bao, OU Kawalekar, P Fagone, ... PLoS neglected tropical diseases 5 (1), e928, 2011 | 215 | 2011 |
| DNA vaccines for targeting bacterial infections M Ingolotti, O Kawalekar, DJ Shedlock, K Muthumani, DB Weiner Expert review of vaccines 9 (7), 747-763, 2010 | 182 | 2010 |
| Monkeying around with HIV vaccines: using rhesus macaques to define'gatekeepers' for clinical trials DJ Shedlock, G Silvestri, DB Weiner Nature Reviews Immunology 9 (10), 717-728, 2009 | 158 | 2009 |
| A specific role for B cells in the generation of CD8 T cell memory by recombinant Listeria monocytogenes H Shen, JK Whitmire, X Fan, DJ Shedlock, SM Kaech, R Ahmed The Journal of Immunology 170 (3), 1443-1451, 2003 | 150 | 2003 |
| Antibody-mediated neutralization of Ebola virus can occur by two distinct mechanisms DJ Shedlock, MA Bailey, PM Popernack, JM Cunningham, DR Burton, ... Virology 401 (2), 228-235, 2010 | 100 | 2010 |
| Th1 and Th2 cells help CD8 T-cell responses MJ Ekkens, DJ Shedlock, EH Jung, A Troy, EL Pearce, H Shen, EJ Pearce Infection and immunity 75 (5), 2291-2296, 2007 | 95 | 2007 |
| Human immunodeficiency virus type 1 Nef induces programmed death 1 expression through a p38 mitogen-activated protein kinase-dependent mechanism K Muthumani, AY Choo, DJ Shedlock, DJ Laddy, SG Sundaram, L Hirao, ... Journal of virology 82 (23), 11536-11544, 2008 | 90 | 2008 |
| Efficacy and safety of P-Bcma-101 CAR-T cells in patients with relapsed/refractory (r/r) multiple myeloma (MM) T Gregory, AD Cohen, CL Costello, SA Ali, JG Berdeja, EM Ostertag, ... Blood 132, 1012, 2018 | 89 | 2018 |
| Induction of broad cytotoxic T cells by protective DNA vaccination against Marburg and Ebola DJ Shedlock, J Aviles, KT Talbott, G Wong, SJ Wu, DO Villarreal, ... Molecular therapy 21 (7), 1432-1444, 2013 | 87 | 2013 |
| Enhanced antigen presenting ability of RNA CAR T cells by co-introduction of costimulatory molecules Y Zhao, DJ Shedlock, CH June, X Liu US Patent 11,028,143, 2021 | 74 | 2021 |
| Phase 1/2 study of the safety and response of P-BCMA-101 CAR-T cells in patients with relapsed/refractory (r/r) multiple myeloma (MM)(PRIME) with novel therapeutic strategies CL Costello, AD Cohen, KK Patel, SS Ali, JG Berdeja, N Shah, S Ganguly, ... Blood 136, 29-30, 2020 | 71 | 2020 |
| Functional characterization of MHC class II-restricted CD8+ CD4− and CD8− CD4− T cell responses to infection in CD4−/− mice EL Pearce, DJ Shedlock, H Shen The Journal of Immunology 173 (4), 2494-2499, 2004 | 69 | 2004 |
| IL-28B/IFN-λ3 drives granzyme B loading and significantly increases CTL killing activity in macaques MP Morrow, J Yan, P Pankhong, DJ Shedlock, MG Lewis, K Talbott, ... Molecular Therapy 18 (9), 1714-1723, 2010 | 66 | 2010 |
| A single dose respiratory recombinant adenovirus-based vaccine provides long-term protection for non-human primates from lethal Ebola infection JH Choi, K Jonsson-Schmunk, X Qiu, DJ Shedlock, J Strong, JX Xu, ... Molecular pharmaceutics 12 (8), 2712-2731, 2015 | 65 | 2015 |
Hao ShenProfessor of MicrobiologyVerified email at pennmedicine.upenn.edu
