| Adverse outcome pathway (AOP) development I: strategies and principles DL Villeneuve, D Crump, N Garcia-Reyero, M Hecker, TH Hutchinson, ... Toxicological Sciences 142 (2), 312-320, 2014 | 284 | 2014 |
| Origin of hydroxylated brominated diphenyl ethers: natural compounds or man-made flame retardants? Y Wan, S Wiseman, H Chang, X Zhang, PD Jones, M Hecker, K Kannan, ... Environmental science & technology 43 (19), 7536-7542, 2009 | 218 | 2009 |
| Synthetic musks in the environment. Part 1: Species-dependent bioaccumulation of polycyclic and nitro musk fragrances in freshwater fish and mussels R Gatermann, S Biselli, H Hühnerfuss, GG Rimkus, M Hecker, L Karbe Archives of Environmental Contamination and Toxicology 42 (4), 437-446, 2002 | 188 | 2002 |
| Adverse outcome pathways and ecological risk assessment: Bridging to population‐level effects VJ Kramer, MA Etterson, M Hecker, CA Murphy, G Roesijadi, DJ Spade, ... Environmental Toxicology and Chemistry 30 (1), 64-76, 2011 | 175 | 2011 |
| Human adrenocarcinoma (H295R) cells for rapid in vitro determination of effects on steroidogenesis: hormone production M Hecker, JL Newsted, MB Murphy, EB Higley, PD Jones, R Wu, JP Giesy Toxicology and applied pharmacology 217 (1), 114-124, 2006 | 167 | 2006 |
| Polybrominated diphenyl ethers and their hydroxylated/methoxylated analogs: environmental sources, metabolic relationships, and relative toxicities SB Wiseman, Y Wan, H Chang, X Zhang, M Hecker, PD Jones, JP Giesy Marine pollution bulletin 63 (5-12), 179-188, 2011 | 165 | 2011 |
| Adverse outcome pathway development II: best practices DL Villeneuve, D Crump, N Garcia-Reyero, M Hecker, TH Hutchinson, ... Toxicological Sciences 142 (2), 321-330, 2014 | 147 | 2014 |
| Effects of atrazine on metamorphosis, growth, laryngeal and gonadal development, aromatase activity, and sex steroid concentrations in Xenopus laevis KK Coady, MB Murphy, DL Villeneuve, M Hecker, PD Jones, JA Carr, ... Ecotoxicology and environmental safety 62 (2), 160-173, 2005 | 144 | 2005 |
| Effect of perinatal and postnatal bisphenol A exposure to the regulatory circuits at the hypothalamus–pituitary–gonadal axis of CD-1 mice W Xi, CKF Lee, WSB Yeung, JP Giesy, MH Wong, X Zhang, M Hecker, ... Reproductive toxicology 31 (4), 409-417, 2011 | 141 | 2011 |
| Plasma biomarkers in fish provide evidence for endocrine modulation in the Elbe River, Germany M Hecker, CR Tyler, M Hoffmann, S Maddix, L Karbe Environmental science & technology 36 (11), 2311-2321, 2002 | 137 | 2002 |
| Atrazine concentrations, gonadal gross morphology and histology in ranid frogs collected in Michigan agricultural areas MB Murphy, M Hecker, KK Coady, AR Tompsett, PD Jones, LH Du Preez, ... Aquatic toxicology 76 (3-4), 230-245, 2006 | 134 | 2006 |
| Real-time PCR array to study effects of chemicals on the hypothalamic–pituitary–gonadal axis of the Japanese medaka X Zhang, M Hecker, JW Park, AR Tompsett, J Newsted, K Nakayama, ... Aquatic Toxicology 88 (3), 173-182, 2008 | 131 | 2008 |
| Toxicity of untreated and ozone-treated oil sands process-affected water (OSPW) to early life stages of the fathead minnow (Pimephales promelas) Y He, S Patterson, N Wang, M Hecker, JW Martin, MG El-Din, JP Giesy, ... Water research 46 (19), 6359-6368, 2012 | 130 | 2012 |
| Effects of 20 PBDE metabolites on steroidogenesis in the H295R cell line Y He, MB Murphy, MK Richard, MHW Lam, M Hecker, JP Giesy, RSS Wu, ... Toxicology Letters 176 (3), 230-238, 2008 | 122 | 2008 |
| Quantitative RT-PCR methods for evaluating toxicant-induced effects on steroidogenesis using the H295R cell line X Zhang, RMK Yu, PD Jones, GKW Lam, JL Newsted, T Gracia, M Hecker, ... Environmental science & technology 39 (8), 2777-2785, 2005 | 107 | 2005 |
| Interconversion of hydroxylated and methoxylated polybrominated diphenyl ethers in Japanese medaka Y Wan, F Liu, S Wiseman, X Zhang, H Chang, M Hecker, PD Jones, ... Environmental science & technology 44 (22), 8729-8735, 2010 | 101 | 2010 |
| The H295R system for evaluation of endocrine-disrupting effects T Gracia, K Hilscherova, PD Jones, JL Newsted, X Zhang, M Hecker, ... Ecotoxicology and environmental safety 65 (3), 293-305, 2006 | 99 | 2006 |
| Endocrine disruptor screening: regulatory perspectives and needs M Hecker, H Hollert Environmental Sciences Europe 23 (1), 15, 2011 | 97 | 2011 |
| Plasma concentrations of estradiol and testosterone, gonadal aromatase activity and ultrastructure of the testis in Xenopus laevis exposed to estradiol or atrazine M Hecker, WJ Kim, JW Park, MB Murphy, D Villeneuve, KK Coady, ... Aquatic Toxicology 72 (4), 383-396, 2005 | 97 | 2005 |
| Bisphenol A disrupts steroidogenesis in human H295R cells X Zhang, H Chang, S Wiseman, Y He, E Higley, P Jones, CKC Wong, ... Toxicological Sciences 121 (2), 320-327, 2011 | 94 | 2011 |
John GiesyProfessor and Canada Research Chair in Environmental Toxicology, University of SaskatchewanVerified email at usask.ca