Owen Skinner
Owen Skinner
Harvard Medical School
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Cited by
Top down proteomics: facts and perspectives
AD Catherman, OS Skinner, NL Kelleher
Biochemical and biophysical research communications 445 (4), 683-693, 2014
MitoCarta3. 0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations
S Rath, R Sharma, R Gupta, T Ast, C Chan, TJ Durham, RP Goodman, ...
Nucleic acids research 49 (D1), D1541-D1547, 2021
Top-down characterization of endogenous protein complexes with native proteomics
OS Skinner, NA Haverland, L Fornelli, RD Melani, LHF Do Vale, ...
Nature chemical biology 14 (1), 36-41, 2018
How ubiquitin unfolds after transfer into the gas phase
OS Skinner, FW McLafferty, K Breuker
Journal of the American Society for Mass Spectrometry 23 (6), 1011-1014, 2012
Applying label-free quantitation to top down proteomics
I Ntai, K Kim, RT Fellers, OS Skinner, AD Smith IV, BP Early, JP Savaryn, ...
Analytical chemistry 86 (10), 4961-4968, 2014
Genetic screen for cell fitness in high or low oxygen highlights mitochondrial and lipid metabolism
IH Jain, SE Calvo, AL Markhard, OS Skinner, TL To, T Ast, VK Mootha
Cell 181 (3), 716-727. e11, 2020
The biosynthesis of methanobactin
GE Kenney, LMK Dassama, ME Pandelia, AS Gizzi, RJ Martinie, P Gao, ...
Science 359 (6382), 1411-1416, 2018
Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell
E Mick, DV Titov, OS Skinner, R Sharma, AA Jourdain, VK Mootha
Elife 9, e49178, 2020
Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome
SE Siegmund, H Yang, R Sharma, M Javors, O Skinner, V Mootha, ...
Human molecular genetics 26 (23), 4588-4605, 2017
An informatic framework for decoding protein complexes by top-down mass spectrometry
OS Skinner, PC Havugimana, NA Haverland, L Fornelli, BP Early, ...
Nature methods 13 (3), 237-240, 2016
Mapping proteoforms and protein complexes from king cobra venom using both denaturing and native top-down proteomics
RD Melani, OS Skinner, L Fornelli, GB Domont, PD Compton, NL Kelleher
Molecular & Cellular Proteomics 15 (7), 2423-2434, 2016
Hepatic NADH reductive stress underlies common variation in metabolic traits
RP Goodman, AL Markhard, H Shah, R Sharma, OS Skinner, CB Clish, ...
Nature 583 (7814), 122-126, 2020
An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD+ imbalance
A Patgiri, OS Skinner, Y Miyazaki, G Schleifer, E Marutani, H Shah, ...
Nature Biotechnology 38 (3), 309-313, 2020
Circulating markers of NADH-reductive stress correlate with mitochondrial disease severity
R Sharma, B Reinstadler, K Engelstad, OS Skinner, E Stackowitz, ...
The Journal of Clinical Investigation 131 (2), 2021
Defining gas-phase fragmentation propensities of intact proteins during native top-down mass spectrometry
NA Haverland, OS Skinner, RT Fellers, AA Tariq, BP Early, RD LeDuc, ...
Journal of The American Society for Mass Spectrometry 28 (6), 1203-1215, 2017
Native GELFrEE: a new separation technique for biomolecular assemblies
OS Skinner, LHF Do Vale, AD Catherman, PC Havugimana, MV Sousa, ...
Analytical chemistry 87 (5), 3032-3038, 2015
Analyzing internal fragmentation of electrosprayed ubiquitin ions during beam-type collisional dissociation
KR Durbin, OS Skinner, RT Fellers, NL Kelleher
Journal of the American Society for Mass Spectrometry 26 (5), 782-787, 2015
Illuminating the dark matter of shotgun proteomics
OS Skinner, NL Kelleher
Nature biotechnology 33 (7), 717-718, 2015
Fragmentation of integral membrane proteins in the gas phase
OS Skinner, AD Catherman, BP Early, PM Thomas, PD Compton, ...
Analytical chemistry 86 (9), 4627-4634, 2014
Characterizing the structure and oligomerization of major royal jelly protein 1 (MRJP1) by mass spectrometry and complementary biophysical tools
SC Mandacaru, LHF do Vale, S Vahidi, Y Xiao, OS Skinner, CAO Ricart, ...
Biochemistry 56 (11), 1645-1655, 2017
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