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Luuk Loeff
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TUT 7 controls the fate of precursor micro RNA s by using three different uridylation mechanisms
B Kim*, M Ha*, L Loeff*, H Chang, DK Simanshu, S Li, M Fareh, DJ Patel, ...
The EMBO journal 34 (13), 1801-1815, 2015
1252015
Two distinct DNA binding modes guide dual roles of a CRISPR-Cas protein complex
TR Blosser*, L Loeff*, ER Westra, M Vlot, T Künne, M Sobota, C Dekker, ...
Molecular cell 58 (1), 60-70, 2015
1182015
Repetitive DNA Reeling by the Cascade-Cas3 Complex in Nucleotide Unwinding Steps
L Loeff, SJJ Brouns, C Joo
Molecular Cell 70 (3), 385–394, 2018
682018
Selective loading and processing of prespacers for precise CRISPR adaptation
S Kim*, L Loeff*, S Colombo, S Jergic, SJJ Brouns, C Joo
Nature 579 (7797), 141-145, 2020
542020
R-loop formation and conformational activation mechanisms of Cas9
M Pacesa, L Loeff, I Querques, LM Muckenfuss, M Sawicka, M Jinek
Nature 609 (7925), 191-196, 2022
50*2022
AutoStepfinder: A fast and automated step detection method for single-molecule analysis
L Loeff*, JWJ Kerssemakers*, C Joo, C Dekker, E contribution
Patterns 2 (5), 100256, 2021
322021
Proteome Adaptation of Saccharomyces cerevisiae to Severe Calorie Restriction in Retentostat Cultures
NA Binai, MMM Bisschops, B van Breukelen, S Mohammed, L Loeff, ...
Journal of proteome research 13 (8), 3542-3553, 2014
202014
Single-molecule pull-down for investigating protein–nucleic acid interactions
M Fareh, L Loeff, M Szczepaniak, AC Haagsma, KH Yeom, C Joo
Methods 105, 99-108, 2016
152016
Mechanistic basis for oxidative stress protection of the human tRNA ligase complex by the oxidoreductase PYROXD1
L Loeff*, A Kroupova*, I Asanovic, FM Boneberg, MM Pfleiderer, A Ferdigg, ...
bioRxiv, 2023.04. 06.535761, 2023
32023
Microbial warfare: illuminating CRISPR adaptive immunity using single-molecule fluorescence
L Loeff
22017
DNA end sensing and cleavage by the Shedu anti-phage defense system
L Loeff, A Walter, GT Rosalen, M Jinek
bioRxiv, 2023.08. 10.552762, 2023
12023
Biophysics of RNA-Guided CRISPR Immunity
L Loeff, C Joo
Biophysics of RNA-Protein Interactions: A Mechanistic View, 189-210, 2019
2019
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Articles 1–12