| Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers A Shlien, BB Campbell, R De Borja, LB Alexandrov, D Merico, D Wedge, ... Nature genetics 47 (3), 257-262, 2015 | 369 | 2015 |
| H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis AS Harutyunyan, B Krug, H Chen, S Papillon-Cavanagh, M Zeinieh, ... Nature communications 10 (1), 1262, 2019 | 263 | 2019 |
| Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome T Gayden, FE Sepulveda, DA Khuong-Quang, J Pratt, ET Valera, ... Nature genetics 50 (12), 1650-1657, 2018 | 180 | 2018 |
| Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas B Krug, N De Jay, AS Harutyunyan, S Deshmukh, DM Marchione, ... Cancer cell 35 (5), 782-797. e8, 2019 | 176 | 2019 |
| PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism SU Jain, TJ Do, PJ Lund, AQ Rashoff, KL Diehl, M Cieslik, A Bajic, ... Nature communications 10 (1), 2146, 2019 | 161 | 2019 |
| Histone H3. 3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis CCL Chen, S Deshmukh, S Jessa, D Hadjadj, V Lisi, AF Andrade, D Faury, ... Cell 183 (6), 1617-1633. e22, 2020 | 113 | 2020 |
| H3 K27M and EZHIP impede H3K27-methylation spreading by inhibiting allosterically stimulated PRC2 SU Jain, AQ Rashoff, SD Krabbenhoft, D Hoelper, TJ Do, TJ Gibson, ... Molecular Cell 80 (4), 726-735. e7, 2020 | 96 | 2020 |
| Histone H3. 3 G34 mutations promote aberrant PRC2 activity and drive tumor progression SU Jain, S Khazaei, DM Marchione, SM Lundgren, X Wang, DN Weinberg, ... Proceedings of the National Academy of Sciences 117 (44), 27354-27364, 2020 | 65 | 2020 |
| DNA polymerase and mismatch repair exert distinct microsatellite instability signatures in normal and malignant human cells J Chung, YE Maruvka, S Sudhaman, J Kelly, NJ Haradhvala, V Bianchi, ... Cancer discovery 11 (5), 1176-1191, 2021 | 53 | 2021 |
| H3. 3 G34W promotes growth and impedes differentiation of osteoblast-like mesenchymal progenitors in giant cell tumor of bone S Khazaei, N De Jay, S Deshmukh, LD Hendrikse, W Jawhar, CCL Chen, ... Cancer discovery 10 (12), 1968-1987, 2020 | 53 | 2020 |
| Oncohistones: a roadmap to stalled development S Deshmukh, A Ptack, B Krug, N Jabado The FEBS journal 289 (5), 1315-1328, 2022 | 28 | 2022 |
| Polycomb repressive complex 2 in the driver’s seat of childhood and young adult brain tumours B Krug, AS Harutyunyan, S Deshmukh, N Jabado Trends in Cell Biology 31 (10), 814-828, 2021 | 22 | 2021 |
| Phenotype Driven Analysis of Whole Genome Sequencing Identifies Deep Intronic Variants that Cause Retinal Dystrophies by Aberrant Exonization M Di Scipio, E Tavares, S Deshmukh, I Audo, K Green-Sanderson, ... Investigative Ophthalmology & Visual Science 61 (10), 36-36, 2020 | 21 | 2020 |
| Entering the era of precision medicine in pediatric oncology D Hadjadj, S Deshmukh, N Jabado Nature Medicine 26 (11), 1684-1685, 2020 | 15 | 2020 |
| The neurologist's role in disabling multiple sclerosis: A qualitative study of patient and care provider perspectives Falet JR | 4 | 2019 |
| Author Correction: Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome T Gayden, FE Sepulveda, DA Khuong-Quang, J Pratt, ET Valera, ... Nature genetics 51 (1), 196-196, 2019 | 3 | 2019 |
| Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4) M Jefri, X Zhang, PS Stumpf, L Zhang, H Peng, N Hettige, JF Theroux, ... Human molecular genetics 31 (21), 3715-3728, 2022 | 2 | 2022 |
| Dysregulation of H3K36 Methylation in Cancer and Developmental Disorders S Deshmukh McGill University (Canada), 2021 | 1 | 2021 |
| Non-truncating homozygous deletion in CACNA2D4 mimicking oligocone trichromacy A Vincent, S Deshmukh, T Wright, YG Sanchez, CA Westall, E Heon Investigative Ophthalmology & Visual Science 55 (13), 6427-6427, 2014 | 1 | 2014 |
| H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs B Krug, B Hu, H Chen, A Ptack, X Chen, KH Gretarsson, S Deshmukh, ... bioRxiv, 2023.11. 28.567931, 2023 | | 2023 |
