Simon-Pierre Gravel Ph.D.
Simon-Pierre Gravel Ph.D.
Professeur adjoint, Faculté de pharmacie, Université de Montréal
Verified email at umontreal.ca
TitleCited byYear
mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation
M Morita, SP Gravel, V Chénard, K Sikström, L Zheng, T Alain, V Gandin, ...
Cell metabolism 18 (5), 698-711, 2013
4122013
Metformin directly acts on mitochondria to alter cellular bioenergetics
S Andrzejewski, SP Gravel, M Pollak, J St-Pierre
Cancer & metabolism 2 (1), 12, 2014
2282014
mTOR coordinates protein synthesis, mitochondrial activity and proliferation
M Morita, SP Gravel, L Hulea, O Larsson, M Pollak, J St-Pierre, ...
Cell cycle 14 (4), 473-480, 2015
1712015
nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs
V Gandin, L Masvidal, L Hulea, SP Gravel, M Cargnello, S McLaughlan, ...
Genome research 26 (5), 636-648, 2016
1062016
AMPK maintains cellular metabolic homeostasis through regulation of mitochondrial reactive oxygen species
RC Rabinovitch, B Samborska, B Faubert, EH Ma, SP Gravel, ...
Cell reports 21 (1), 1-9, 2017
1032017
PGC-1α supports glutamine metabolism in breast cancer
S McGuirk, SP Gravel, G Deblois, DJ Papadopoli, B Faubert, A Wegner, ...
Cancer & metabolism 1 (1), 22, 2013
932013
Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association
JF Clément, A Bibeau-Poirier, SP Gravel, N Grandvaux, É Bonneil, ...
Journal of virology 82 (8), 3984-3996, 2008
892008
Involvement of the IκB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation
A Bibeau-Poirier, SP Gravel, JF Clément, S Rolland, G Rodier, ...
The Journal of Immunology 177 (8), 5059-5067, 2006
892006
Involvement of the IκB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation
A Bibeau-Poirier, SP Gravel, JF Clément, S Rolland, G Rodier, ...
The Journal of Immunology 177 (8), 5059-5067, 2006
892006
The proinflammatory actions of angiotensin II are dependent on p65 phosphorylation by the IκB kinase complex
A Douillette, A Bibeau-Poirier, SP Gravel, JF Clément, V Chénard, ...
Journal of Biological Chemistry 281 (19), 13275-13284, 2006
862006
Serine deprivation enhances antineoplastic activity of biguanides
SP Gravel, L Hulea, N Toban, E Birman, MJ Blouin, M Zakikhani, Y Zhao, ...
Cancer research 74 (24), 7521-7533, 2014
542014
The PGC-1α/ERRα axis represses one-carbon metabolism and promotes sensitivity to anti-folate therapy in breast cancer
E Audet-Walsh, DJ Papadopoli, SP Gravel, T Yee, G Bridon, M Caron, ...
Cell reports 14 (4), 920-931, 2016
422016
The PGC-1α/ERRα axis represses one-carbon metabolism and promotes sensitivity to anti-folate therapy in breast cancer
E Audet-Walsh, DJ Papadopoli, SP Gravel, T Yee, G Bridon, M Caron, ...
Cell reports 14 (4), 920-931, 2016
422016
Roles of an IκB Kinase-related Pathway in Human Cytomegalovirus-infected Vascular Smooth Muscle Cells A MOLECULAR LINK IN PATHOGEN-INDUCED PROATHEROSCLEROTIC CONDITIONS
SP Gravel, MJ Servant
Journal of Biological Chemistry 280 (9), 7477-7486, 2005
422005
ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer
G Deblois, HW Smith, IS Tam, SP Gravel, M Caron, P Savage, DP Labbé, ...
Nature communications 7 (1), 1-14, 2016
342016
The complete targeted profile of the organic acid intermediates of the citric acid cycle using a single stable isotope dilution analysis, sodium borodeuteride reduction and …
O Mamer, SP Gravel, L Choiniere, V Chénard, J St-Pierre, D Avizonis
Metabolomics 9 (5), 1019-1030, 2013
292013
Stable isotope tracer analysis in isolated mitochondria from mammalian systems
SP Gravel, S Andrzejewski, D Avizonis, J St-Pierre
Metabolites 4 (2), 166-183, 2014
202014
Ché nard V
M Morita, SP Gravel
Sikstro m K, Zheng L, Alain T, Gandin V, Avizonis D, Arguello M, Zakaria C …, 2013
182013
Translational and HIF-1α-dependent metabolic reprogramming underpin metabolic plasticity and responses to kinase inhibitors and biguanides
L Hulea, SP Gravel, M Morita, M Cargnello, O Uchenunu, YK Im, ...
Cell metabolism 28 (6), 817-832. e8, 2018
152018
PRL2 links magnesium flux and sex-dependent circadian metabolic rhythms
N Uetani, S Hardy, SP Gravel, S Kiessling, A Pietrobon, NN Wong, ...
JCI insight 2 (13), 2017
122017
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