catherine vilcheze
catherine vilcheze
Albert Einstein College of Medicine
Verified email at
Cited by
Cited by
Mechanisms of Drug Resistance in Mycobacterium tuberculosis
Y Zhang, C Vilchčze, WR Jacobs JR
Tuberculosis and the tubercle bacillus, 115-140, 2004
Effect of the structure of natural sterols and sphingolipids on the formation of ordered sphingolipid/sterol domains (rafts)
X Xu, R Bittman, G Duportail, D Heissler, C Vilcheze, E London
Journal of Biological Chemistry 276 (36), 33540-33546, 2001
Enzymic characterization of the target for isoniazid in Mycobacterium tuberculosis
A Quemard, JC Sacchettini, A Dessen, C Vilcheze, R Bittman, ...
Biochemistry 34 (26), 8235-8241, 1995
The mechanism of isoniazid killing: clarity through the scope of genetics
C Vilchčze, WR Jacobs, Jr
Annu. Rev. Microbiol. 61, 35-50, 2007
Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid
C Vilchčze, F Wang, M Arai, MH Hazbón, R Colangeli, L Kremer, ...
Nature medicine 12 (9), 1027-1029, 2006
Pyrazinamide inhibits the eukaryotic-like fatty acid synthetase I (FASI) of Mycobacterium tuberculosis
O Zimhony, JS Cox, JT Welch, C Vilcheze, WR Jacobs
Nature medicine 6 (9), 1043-1047, 2000
Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of …
C Vilchèze, HR Morbidoni, TR Weisbrod, H Iwamoto, M Kuo, ...
Journal of bacteriology 182 (14), 4059-4067, 2000
Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate
DA Rozwarski, C Vilcheze, M Sugantino, R Bittman, JC Sacchettini
Journal of Biological Chemistry 274 (22), 15582-15589, 1999
Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction
C Vilchčze, T Hartman, B Weinrick, WR Jacobs Jr
Nature communications 4 (1), 1881, 2013
Altered NADH/NAD+ Ratio Mediates Coresistance to Isoniazid and Ethionamide in Mycobacteria
C Vilcheze, TR Weisbrod, B Chen, L Kremer, MH Hazbón, F Wang, ...
Antimicrobial agents and chemotherapy 49 (2), 708-720, 2005
The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites
M Yu, TRS Kumar, LJ Nkrumah, A Coppi, S Retzlaff, CD Li, BJ Kelly, ...
Cell host & microbe 4 (6), 567-578, 2008
Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis
MB Harbut, C Vilchčze, X Luo, ME Hensler, H Guo, B Yang, AK Chatterjee, ...
Proceedings of the National Academy of Sciences 112 (14), 4453-4458, 2015
Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis
MH Larsen, C Vilchčze, L Kremer, GS Besra, L Parsons, M Salfinger, ...
Molecular microbiology 46 (2), 453-466, 2002
Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis: Genes, Mutations, and Causalities
C Vilchčze, WR Jacobs Jr
Molecular genetics of Mycobacteria, 431-453, 2014
Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis
C Vilchčze, Y Av‐Gay, R Attarian, Z Liu, MH Hazbón, R Colangeli, B Chen, ...
Molecular microbiology 69 (5), 1316-1329, 2008
Separable roles for Mycobacterium tuberculosis ESX-3 effectors in iron acquisition and virulence
JAM Tufariello, JR Chapman, CA Kerantzas, KW Wong, C Vilchčze, ...
Proceedings of the National Academy of Sciences 113 (3), E348-E357, 2016
Energetics of respiration and oxidative phosphorylation in mycobacteria
GM Cook, K Hards, C Vilchčze, T Hartman, M Berney
Molecular Genetics of Mycobacteria, 389-409, 2014
Trichoderins, novel aminolipopeptides from a marine sponge-derived Trichoderma sp., are active against dormant mycobacteria
P Pruksakorn, M Arai, N Kotoku, C Vilchčze, AD Baughn, P Moodley, ...
Bioorganic & medicinal chemistry letters 20 (12), 3658-3663, 2010
Triclosan Derivatives: Towards Potent Inhibitors of Drug‐Sensitive and Drug‐Resistant Mycobacterium tuberculosis
JS Freundlich, F Wang, C Vilchčze, G Gulten, R Langley, GA Schiehser, ...
ChemMedChem: Chemistry Enabling Drug Discovery 4 (2), 241-248, 2009
Enhanced respiration prevents drug tolerance and drug resistance in Mycobacterium tuberculosis
C Vilchčze, T Hartman, B Weinrick, P Jain, TR Weisbrod, LW Leung, ...
Proceedings of the National Academy of Sciences 114 (17), 4495-4500, 2017
The system can't perform the operation now. Try again later.
Articles 1–20