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Dr. Michaela Gack
Dr. Michaela Gack
Scientific Director and Chair, Cleveland Clinic Florida Research and Innovation Center
Verified email at ccf.org
Title
Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
107022021
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
MU Gack, YC Shin, CH Joo, T Urano, C Liang, L Sun, O Takeuchi, S Akira, ...
Nature 446 (7138), 916-920, 2007
18332007
RIG-I-like receptors: their regulation and roles in RNA sensing
J Rehwinkel, MU Gack
Nature Reviews Immunology 20 (9), 537-551, 2020
10722020
Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I
MU Gack, RA Albrecht, T Urano, KS Inn, IC Huang, E Carnero, M Farzan, ...
Cell host & microbe 5 (5), 439-449, 2009
10022009
Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking
C Liang, J Lee, KS Inn, MU Gack, Q Li, EA Roberts, I Vergne, V Deretic, ...
Nature cell biology 10 (7), 776-787, 2008
9372008
Dysregulation of type I interferon responses in COVID-19
D Acharya, GQ Liu, MU Gack
Nature Reviews Immunology 20 (7), 397-398, 2020
4632020
Viral evasion of intracellular DNA and RNA sensing
YK Chan, MU Gack
Nature Reviews Microbiology 14 (6), 360-373, 2016
4612016
Cytosolic viral sensor RIG-I is a 5'-Triphosphate–dependent translocase on double-stranded RNA
S Myong, S Cui, PV Cornish, A Kirchhofer, MU Gack, JU Jung, ...
Science 323 (5917), 1070-1074, 2009
4472009
Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein
R Rajsbaum, RA Albrecht, MK Wang, NP Maharaj, GA Versteeg, ...
PLoS pathogens 8 (11), e1003059, 2012
3372012
Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling
E Wies, MK Wang, NP Maharaj, K Chen, S Zhou, RW Finberg, MU Gack
Immunity 38 (3), 437-449, 2013
3322013
Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction
MU Gack, A Kirchhofer, YC Shin, KS Inn, C Liang, S Cui, S Myong, T Ha, ...
Proceedings of the National Academy of Sciences 105 (43), 16743-16748, 2008
3072008
TRIM proteins and their roles in antiviral host defenses
M van Gent, KMJ Sparrer, MU Gack
Annual review of virology 5, 385-405, 2018
2532018
Linear ubiquitin assembly complex negatively regulates RIG-I-and TRIM25-mediated type I interferon induction
KS Inn, MU Gack, F Tokunaga, M Shi, LY Wong, K Iwai, JU Jung
Molecular cell 41 (3), 354-365, 2011
2242011
Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity
JJ Chiang, KMJ Sparrer, M van Gent, C Lässig, T Huang, N Osterrieder, ...
Nature immunology 19 (1), 53-62, 2018
2102018
ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity
GQ Liu, JH Lee, ZM Parker, D Acharya, JJ Chiang, M van Gent, W Riedl, ...
Nature microbiology 6 (4), 467-478, 2021
2092021
A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19
Y Zhou, Y Hou, J Shen, R Mehra, A Kallianpur, DA Culver, MU Gack, ...
PLoS biology 18 (11), e3000970, 2020
1892020
Ubiquitination in the antiviral immune response
ME Davis, MU Gack
Virology 479, 52-65, 2015
1802015
RIG-I-like receptor regulation in virus infection and immunity
YK Chan, MU Gack
Current opinion in virology 12, 7-14, 2015
1792015
TRIM23 mediates virus-induced autophagy via activation of TBK1
KMJ Sparrer, S Gableske, MA Zurenski, ZM Parker, F Full, GJ Baumgart, ...
Nature microbiology 2 (11), 1543-1557, 2017
1692017
The ubiquitin-specific protease USP15 promotes RIG-I–mediated antiviral signaling by deubiquitylating TRIM25
EK Pauli, YK Chan, ME Davis, S Gableske, MK Wang, KF Feister, ...
Science signaling 7 (307), ra3-ra3, 2014
1622014
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Articles 1–20