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Howard Clark
Howard Clark
Professor of Child Health, University of Southampton
Verified email at soton.ac.uk
Title
Cited by
Cited by
Year
Surfactant proteins A and D protect mice against pulmonary hypersensitivity induced by Aspergillus fumigatus antigens and allergens
T Madan, U Kishore, M Singh, P Strong, H Clark, EM Hussain, KBM Reid, ...
The Journal of clinical investigation 107 (4), 467-475, 2001
2602001
Nucleic acid is a novel ligand for innate, immune pattern recognition collectins surfactant proteins A and D and mannose-binding lectin
N Palaniyar, J Nadesalingam, H Clark, MJ Shih, AW Dodds, KBM Reid
Journal of Biological Chemistry 279 (31), 32728-32736, 2004
2232004
Surfactant protein D reduces alveolar macrophage apoptosis in vivo
H Clark, N Palaniyar, P Strong, J Edmondson, S Hawgood, KBM Reid
The Journal of Immunology 169 (6), 2892-2899, 2002
2232002
The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation
FR Svedberg, SL Brown, MZ Krauss, L Campbell, C Sharpe, M Clausen, ...
Nature immunology 20 (5), 571-580, 2019
1692019
Specificity and rate of human and mouse liver and plasma phosphatidylcholine synthesis analyzed in vivo
CJ Pynn, NG Henderson, H Clark, G Koster, W Bernhard, AD Postle
Journal of lipid research 52 (2), 399-407, 2011
1592011
Clinical signs predict 30-month neurodevelopmental outcome after neonatal encephalopathy
SP Miller, B Latal, H Clark, A Barnwell, D Glidden, AJ Barkovich, ...
American journal of obstetrics and gynecology 190 (1), 93-99, 2004
1552004
Pulmonary collectins modulate strain-specific influenza a virus infection and host responses
S Hawgood, C Brown, J Edmondson, A Stumbaugh, L Allen, J Goerke, ...
Journal of Virology 78 (16), 8565-8572, 2004
1492004
Recent advances in alveolar biology: evolution and function of alveolar proteins
S Orgeig, PS Hiemstra, EJA Veldhuizen, C Casals, HW Clark, A Haczku, ...
Respiratory physiology & neurobiology 173, S43-S54, 2010
1382010
Intranasal application of chitin microparticles down‐regulates symptoms of allergic hypersensitivity to Dermatophagoides pteronyssinus and Aspergillus fumigatus in murine …
P Strong, H Clark, K Reid
Clinical & Experimental Allergy 32 (12), 1794-1800, 2002
1332002
Intranasal delivery of a truncated recombinant human SP‐D is effective at down‐regulating allergic hypersensitivity in mice sensitized to allergens of Aspergillus fumigatus
P Strong, KBM Reid, H Clark
Clinical & Experimental Immunology 130 (1), 19-24, 2002
1102002
Major house dust mite allergens Dermatophagoides pteronyssinus 1 and Dermatophagoides farinae 1 degrade and inactivate lung surfactant proteins A and D
R Deb, F Shakib, K Reid, H Clark
Journal of Biological Chemistry 282 (51), 36808-36819, 2007
1032007
Truncated recombinant human SP-D attenuates emphysema and type II cell changes in SP-D deficient mice
L Knudsen, M Ochs, R MacKay, P Townsend, R Deb, C Mühlfeld, ...
Respiratory research 8 (1), 70, 2007
972007
Mechanism of neutrophil dysfunction: neutrophil serine proteases cleave and inactivate the C5a receptor
CW van den Berg, DV Tambourgi, HW Clark, SJ Hoong, OB Spiller, ...
The Journal of Immunology 192 (4), 1787-1795, 2014
932014
Innate immune collectin surfactant protein D enhances the clearance of DNA by macrophages and minimizes anti-DNA antibody generation
N Palaniyar, H Clark, J Nadesalingam, MJ Shih, S Hawgood, KBM Reid
The Journal of Immunology 174 (11), 7352-7358, 2005
822005
Surfactant phospholipids, surfactant proteins, and inflammatory markers during acute lung injury in children
DA Todd, MJ Marsh, A George, NG Henderson, H Barr, S Sebastian, ...
Pediatric Critical Care Medicine 11 (1), 82-91, 2010
812010
A recombinant fragment of human surfactant protein D reduces alveolar macrophage apoptosis and pro‐inflammatory cytokines in mice developing pulmonary emphysema
H Clark, N Palaniyar, S Hawgood, KBM Reid
Annals of the New York Academy of Sciences 1010 (1), 113-116, 2003
802003
Surfactant Protein D Binds Genomic DNA and Apoptotic Cells, and Enhances Their Clearance, in Vivo
N Palaniyar, H Clark, J Nadesalingam, S Hawgood, KB Reid
Annals of the New York Academy of Sciences 1010 (1), 471-475, 2003
802003
The potential of recombinant surfactant protein D therapy to reduce inflammation in neonatal chronic lung disease, cystic fibrosis, and emphysema
H Clark, K Reid
Archives of disease in childhood 88 (11), 981-984, 2003
762003
Collectins and their role in lung immunity
TP Hickling, H Clark, R Malhotra, RB Sim
Journal of leukocyte biology 75 (1), 27-33, 2004
752004
Surfactant protein D (SP-D) alters cellular uptake of particles and nanoparticles
M Kendall, P Ding, RM Mackay, R Deb, Z McKenzie, K Kendall, J Madsen, ...
Nanotoxicology 7 (5), 963-973, 2013
742013
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