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Changmeng Cai
Changmeng Cai
Verified email at umb.edu
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Year
EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent
K Xu, ZJ Wu, AC Groner, HH He, C Cai, RT Lis, X Wu, EC Stack, M Loda, ...
Science 338 (6113), 1465-1469, 2012
9372012
Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1
C Cai, HH He, S Chen, I Coleman, H Wang, Z Fang, S Chen, PS Nelson, ...
Cancer cell 20 (4), 457-471, 2011
4952011
Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 …
C Cai, S Chen, P Ng, GJ Bubley, PS Nelson, EA Mostaghel, B Marck, ...
Cancer research 71 (20), 6503-6513, 2011
4952011
Androgen receptor functions in castration-resistant prostate cancer and mechanisms of resistance to new agents targeting the androgen axis
X Yuan, C Cai, S Chen, Z Yu, SP Balk
Oncogene 33 (22), 2815-2825, 2014
3752014
Rapid induction of androgen receptor splice variants by androgen deprivation in prostate cancer
Z Yu, S Chen, AG Sowalsky, OS Voznesensky, EA Mostaghel, PS Nelson, ...
Clinical cancer research 20 (6), 1590-1600, 2014
2232014
Intratumoral androgen biosynthesis in prostate cancer pathogenesis and response to therapy
C Cai, SP Balk
Endocrine-related cancer 18 (5), R175-R182, 2011
1992011
ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer
C Cai, H Wang, HH He, S Chen, L He, F Ma, L Mucci, Q Wang, C Fiore, ...
The Journal of clinical investigation 123 (3), 1109-1122, 2013
1912013
Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors
EJ Chen, AG Sowalsky, S Gao, C Cai, O Voznesensky, R Schaefer, ...
Clinical cancer research 21 (6), 1273-1280, 2015
1892015
Reactivation of Androgen Receptor–Regulated TMPRSS2: ERG Gene Expression in Castration-Resistant Prostate Cancer
C Cai, H Wang, Y Xu, S Chen, SP Balk
Cancer research 69 (15), 6027-6032, 2009
1712009
SOX9 drives WNT pathway activation in prostate cancer
F Ma, H Ye, HH He, SJ Gerrin, S Chen, BA Tanenbaum, C Cai, ...
The Journal of clinical investigation 126 (5), 1745-1758, 2016
1612016
Lysine-specific demethylase 1 has dual functions as a major regulator of androgen receptor transcriptional activity
C Cai, HH He, S Gao, S Chen, Z Yu, Y Gao, S Chen, MW Chen, J Zhang, ...
Cell reports 9 (5), 1618-1627, 2014
1362014
ETV1 is a novel androgen receptor-regulated gene that mediates prostate cancer cell invasion
C Cai, CL Hsieh, J Omwancha, Z Zheng, SY Chen, JL Baert, ...
Molecular endocrinology 21 (8), 1835-1846, 2007
1322007
Androgen receptor serine 81 phosphorylation mediates chromatin binding and transcriptional activation
S Chen, S Gulla, C Cai, SP Balk
Journal of Biological Chemistry 287 (11), 8571-8583, 2012
1192012
Galeterone prevents androgen receptor binding to chromatin and enhances degradation of mutant androgen receptor
Z Yu, C Cai, S Gao, NI Simon, HC Shen, SP Balk
Clinical cancer research 20 (15), 4075-4085, 2014
1012014
Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer
S Gao, S Chen, D Han, Z Wang, M Li, W Han, A Besschetnova, M Liu, ...
Nature genetics 52 (10), 1011-1017, 2020
902020
Androgen receptor tumor suppressor function is mediated by recruitment of retinoblastoma protein
S Gao, Y Gao, HH He, D Han, W Han, A Avery, JA Macoska, X Liu, ...
Cell reports 17 (4), 966-976, 2016
902016
Reactivation of androgen receptor-regulated lipid biosynthesis drives the progression of castration-resistant prostate cancer
W Han, S Gao, D Barrett, M Ahmed, D Han, JA Macoska, HH He, C Cai
Oncogene 37 (6), 710-721, 2018
882018
Pioneer of prostate cancer: past, present and the future of FOXA1
M Teng, S Zhou, C Cai, M Lupien, HH He
Protein & Cell 12 (1), 29-38, 2021
842021
Androgen receptor enhances p27 degradation in prostate cancer cells through rapid and selective TORC2 activation
Z Fang, T Zhang, N Dizeyi, S Chen, H Wang, KD Swanson, C Cai, ...
Journal of Biological Chemistry 287 (3), 2090-2098, 2012
832012
c-Jun enhancement of androgen receptor transactivation is associated with prostate cancer cell proliferation
SY Chen, C Cai, CJ Fisher, Z Zheng, J Omwancha, CL Hsieh, ...
Oncogene 25 (54), 7212-7223, 2006
802006
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