| Quorum‐sensing regulation of a capsular polysaccharide receptor for the Rhodobacter capsulatus gene transfer agent (RcGTA) CA Brimacombe, A Stevens, D Jun, R Mercer, AS Lang, JT Beatty Molecular microbiology 87 (4), 802-817, 2013 | 86 | 2013 |
| The GtaR protein negatively regulates transcription of the gtaRI operon and modulates gene transfer agent (RcGTA) expression in Rhodobacter capsulatus MM Leung, CA Brimacombe, GB Spiegelman, JT Beatty Molecular microbiology 83 (4), 759-774, 2012 | 57 | 2012 |
| Homologues of genetic transformation DNA import genes are required for Rhodobacter capsulatus gene transfer agent recipient capability regulated by the response regulator CtrA CA Brimacombe, H Ding, JA Johnson, JT Beatty Journal of bacteriology 197 (16), 2653-2663, 2015 | 51 | 2015 |
| Rhodobacter capsulatus DprA is essential for RecA‐mediated gene transfer agent (RcGTA) recipient capability regulated by quorum‐sensing and the CtrA … CA Brimacombe, H Ding, JT Beatty Molecular Microbiology 92 (6), 1260-1278, 2014 | 50 | 2014 |
| The SOS response master regulator LexA regulates the gene transfer agent of Rhodobacter capsulatus and represses transcription of the signal transduction protein CckA KS Kuchinski, CA Brimacombe, AB Westbye, H Ding, JT Beatty Journal of Bacteriology 198 (7), 1137-1148, 2016 | 31 | 2016 |
| Recording of DNA-binding events reveals the importance of a repurposed Candida albicans regulatory network for gut commensalism JN Witchley, P Basso, CA Brimacombe, NV Abon, SM Noble Cell host & microbe 29 (6), 1002-1013. e9, 2021 | 22 | 2021 |
| Transcriptional regulation of the Rhodobacter capsulatus response regulator CtrA MM Leung, CA Brimacombe, JT Beatty Microbiology 159 (Pt_1), 96-106, 2013 | 21 | 2013 |
| Surface polysaccharide extraction and quantification CA Brimacombe, JT Beatty Bio-protocol 3 (20), e934-e934, 2013 | 20 | 2013 |
| Ex vivo expansion of normal and chronic myeloid leukemic stem cells without functional alteration using a NUP98HOXA10homeodomain fusion gene I Sloma, S Imren, PA Beer, Y Zhao, V Lecault, D Leung, K Raghuram, ... Leukemia 27 (1), 159-169, 2013 | 20 | 2013 |
| A natural histone H2A variant lacking the Bub1 phosphorylation site and regulated depletion of centromeric histone CENP-A foster evolvability in Candida albicans CA Brimacombe, JE Burke, JY Parsa, S Catania, TR O’Meara, ... PLoS biology 17 (6), e3000331, 2019 | 17 | 2019 |
| Industrially Applicable De Novo Lager Yeast Hybrids with a Unique Genomic Architecture: Creation and Characterization Z Turgeon, T Sierocinski, CA Brimacombe, Y Jin, B Goldhawke, ... Applied and Environmental Microbiology 87 (3), e02434-20, 2021 | 13 | 2021 |
| Lipid nanoparticles to silence androgen receptor variants for prostate cancer therapy J Quick, N Dos Santos, MHY Cheng, N Chander, CA Brimacombe, ... Journal of Controlled Release 349, 174-183, 2022 | 12 | 2022 |
| Genotypic and functional diversity of phenotypically defined primitive hematopoietic cells in patients with chronic myeloid leukemia I Sloma, PA Beer, KM Saw, M Chan, D Leung, K Raghuram, ... Experimental Hematology 41 (10), 837-847, 2013 | 12 | 2013 |
| Exciting times for lipid nanoparticles: How Canadian discoveries are enabling gene therapies MHY Cheng, CA Brimacombe, R Verbeke, PR Cullis Molecular pharmaceutics 19 (6), 1663-1668, 2022 | 11 | 2022 |
| A white-to-opaque-like phenotypic switch in the yeast Torulaspora microellipsoides CA Brimacombe, T Sierocinski, MS Dahabieh Communications Biology 3 (1), 86, 2020 | 5 | 2020 |
| Identification of a gene involved in the biosynthesis pathway of the terminal sugar of the archaellin N-linked tetrasaccharide in Methanococcus maripaludis Y Ding, GM Jones, C Brimacombe, K Uchida, SI Aizawa, SM Logan, ... Antonie van Leeuwenhoek 109, 131-148, 2016 | 4 | 2016 |
| De Novo Hybridization Approach Expands Diversity of Industrially Applicable Lager Yeast Strains with Unique Genome Composition Z Turgeon, RC Jurgens, T Sierocinski, CA Brimacombe, Y Jin, ... Tech. Q 58, 106-116, 2021 | 3 | 2021 |
| Chromatin rewiring mediates programmed evolvability via aneuploidy CA Brimacombe, JE Burke, JY Parsa, JN Witchley, LS Burrack, ... bioRxiv, 407841, 2018 | 3 | 2018 |
| Epigenetic and functional changes imposed by NUP98-HOXA9 in a genetically engineered model of chronic myeloid leukemia progression I Sloma, P Beer, C Desterke, E Bulaeva, M Bilenky, A Carles, M Moksa, ... haematologica 106 (3), 881, 2021 | 2 | 2021 |
| Yeast for producing and delivering rna bioactive molecules and methods and uses thereof Y Wang, JK Hung, JI Husnik, MS Dahabieh, H Ding, C Snowdon, ... US Patent App. 17/091,564, 2021 | | 2021 |
Susan M LoganPrincipal Research OfficerVerified email at nrc-cnrc.gc.ca
