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Christine A. Iacobuzio-Donahue
Christine A. Iacobuzio-Donahue
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Year
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ...
science 321 (5897), 1801-1806, 2008
46102008
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
KP Olive, MA Jacobetz, CJ Davidson, A Gopinathan, D McIntyre, ...
Science 324 (5933), 1457-1461, 2009
35192009
Genomic analyses identify molecular subtypes of pancreatic cancer
P Bailey, DK Chang, K Nones, AL Johns, AM Patch, MC Gingras, ...
Nature 531 (7592), 47-52, 2016
31432016
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
S Yachida, S Jones, I Bozic, T Antal, R Leary, B Fu, M Kamiyama, ...
Nature 467 (7319), 1114-1117, 2010
29022010
Whole genomes redefine the mutational landscape of pancreatic cancer
N Waddell, M Pajic, AM Patch, DK Chang, KS Kassahn, P Bailey, ...
Nature 518 (7540), 495-501, 2015
26092015
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
PJ Stephens, CD Greenman, B Fu, F Yang, GR Bignell, LJ Mudie, ...
cell 144 (1), 27-40, 2011
25772011
A draft map of the human proteome
MS Kim, SM Pinto, D Getnet, RS Nirujogi, SS Manda, R Chaerkady, ...
Nature 509 (7502), 575-581, 2014
24342014
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ...
Nature 475 (7354), 106-109, 2011
22712011
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ...
Nature 491 (7424), 399-405, 2012
21852012
Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma
AD Rhim, PE Oberstein, DH Thomas, ET Mirek, CF Palermo, SA Sastra, ...
Cancer cell 25 (6), 735-747, 2014
19852014
Organoid models of human and mouse ductal pancreatic cancer
SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ...
Cell 160 (1), 324-338, 2015
19012015
Virtual microdissection identifies distinct tumor-and stroma-specific subtypes of pancreatic ductal adenocarcinoma
RA Moffitt, R Marayati, EL Flate, KE Volmar, SGH Loeza, KA Hoadley, ...
Nature genetics 47 (10), 1168-1178, 2015
17452015
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1666*2020
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
PJ Campbell, S Yachida, LJ Mudie, PJ Stephens, ED Pleasance, ...
Nature 467 (7319), 1109-1113, 2010
15572010
DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer
CA Iacobuzio-Donahue, B Fu, S Yachida, M Luo, H Abe, CM Henderson, ...
Journal of clinical oncology 27 (11), 1806, 2009
11672009
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer
VP Balachandran, M Łuksza, JN Zhao, V Makarov, JA Moral, R Remark, ...
Nature 551 (7681), 512-516, 2017
9862017
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene
S Jones, RH Hruban, M Kamiyama, M Borges, X Zhang, DW Parsons, ...
Science 324 (5924), 217-217, 2009
9472009
Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers
G Feldmann, S Dhara, V Fendrich, D Bedja, R Beaty, M Mullendore, ...
Cancer research 67 (5), 2187-2196, 2007
8512007
Notch mediates TGFα-induced changes in epithelial differentiation during pancreatic tumorigenesis
Y Miyamoto, A Maitra, B Ghosh, U Zechner, P Argani, ...
Cancer cell 3 (6), 565-576, 2003
8352003
Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression
RE Wilentz, CA Iacobuzio-Donahue, P Argani, DM McCarthy, JL Parsons, ...
Cancer research 60 (7), 2002-2006, 2000
8002000
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