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Emma Guns
Emma Guns
Independent Science Consultant
Verified email at koptherapeutics.com - Homepage
Title
Cited by
Cited by
Year
Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
JA Locke, ES Guns, AA Lubik, HH Adomat, SC Hendy, CA Wood, ...
Cancer research 68 (15), 6407-6415, 2008
9472008
Challenges and opportunities in exosome research—Perspectives from biology, engineering, and cancer therapy
X Li, AL Corbett, E Taatizadeh, N Tasnim, JP Little, C Garnis, M Daugaard, ...
APL bioengineering 3 (1), 2019
3912019
Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles
VR Minciacchi, S You, C Spinelli, S Morley, M Zandian, PJ Aspuria, ...
Oncotarget 6 (13), 11327, 2015
3582015
Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance
MJ Newman, JC Rodarte, KD Benbatoul, SJ Romano, C Zhang, S Krane, ...
Cancer research 60 (11), 2964-2972, 2000
2972000
Reproducibility and efficiency of serum-derived exosome extraction methods
J Caradec, G Kharmate, E Hosseini-Beheshti, H Adomat, M Gleave, ...
Clinical biochemistry 47 (13-14), 1286-1292, 2014
2722014
Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes
E Hosseini-Beheshti, S Pham, H Adomat, N Li, EST Guns
Molecular & Cellular Proteomics 11 (10), 863-885, 2012
2532012
Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration‐resistant prostate cancer in a mouse xenograft model
CG Leon, JA Locke, HH Adomat, SL Etinger, AL Twiddy, RD Neumann, ...
The Prostate 70 (4), 390-400, 2010
1932010
Targeting the binding function 3 (BF3) site of the human androgen receptor through virtual screening.
NA Lack, P Axerio-Cilies, P Tavassoli, FQ Han, KH Chan, C Feau, ...
Journal of medicinal chemistry 54 (24), 8563-8573, 2011
1842011
Bioactive compounds from Rhodiola rosea (Crassulaceae)
DS Ming, BJ Hillhouse, ES Guns, A Eberding, S Xie, S Vimalanathan, ...
Phytotherapy Research: An International Journal Devoted to Pharmacological …, 2005
1762005
Lycopene differentially induces quiescence and apoptosis in androgen-responsive and-independent prostate cancer cell lines
NI Ivanov, SP Cowell, P Brown, PS Rennie, ES Guns, ME Cox
Clinical Nutrition 26 (2), 252-263, 2007
1542007
Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer
K Dalal, M Roshan-Moniri, A Sharma, H Li, F Ban, M Hessein, M Hsing, ...
Journal of biological chemistry 289 (38), 26417-26429, 2014
1462014
A population-based survey of complementary and alternative medicine use in men recently diagnosed with prostate cancer
J Eng, D Ramsum, M Verhoef, E Guns, J Davison, R Gallagher
Integrative cancer therapies 2 (3), 212-216, 2003
1462003
A phase I study of OGX-011, a 2′-methoxyethyl phosphorothioate antisense to clusterin, in combination with docetaxel in patients with advanced cancer
KN Chi, LL Siu, H Hirte, SJ Hotte, J Knox, C Kollmansberger, M Gleave, ...
Clinical Cancer Research 14 (3), 833-839, 2008
1352008
Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation.
DM Gentile, ES Tomlinson, JL Maggs, BK Park, DJ Back
Journal of Pharmacology and Experimental Therapeutics 277 (1), 105-112, 1996
1351996
DMSO represses inflammatory cytokine production from human blood cells and reduces autoimmune arthritis
I Elisia, H Nakamura, V Lam, E Hofs, R Cederberg, J Cait, MR Hughes, ...
PloS one 11 (3), e0152538, 2016
1192016
Inhibitors of androgen receptor activation function-2 (AF2) site identified through virtual screening
P Axerio-Cilies, NA Lack, MRS Nayana, KH Chan, A Yeung, E Leblanc, ...
Journal of medicinal chemistry 54 (18), 6197-6205, 2011
1062011
Randomized phase II study of high-dose paclitaxel with or without amifostine in patients with metastatic breast cancer
K Gelmon, E Eisenhauer, C Bryce, A Tolcher, L Mayer, E Tomlinson, ...
Journal of clinical oncology 17 (10), 3038-3047, 1999
1061999
Dexamethasone metabolism in vitro: species differences
ES Tomlinson, JL Maggs, BK Park, DJ Back
The Journal of steroid biochemistry and molecular biology 62 (4), 345-352, 1997
1041997
Anticancer activity of a novel selective CYP17A1 inhibitor in preclinical models of castrate-resistant prostate cancer
PJ Toren, S Kim, S Pham, A Mangalji, H Adomat, EST Guns, A Zoubeidi, ...
Molecular cancer therapeutics 14 (1), 59-69, 2015
982015
Targeting the Binding Function 3 (BF3) Site of the Androgen Receptor Through Virtual Screening. 2. Development of 2-((2-phenoxyethyl) thio)-1H-benzimidazole …
RSN Munuganti, E Leblanc, P Axerio-Cilies, C Labriere, K Frewin, ...
Journal of medicinal chemistry 56 (3), 1136-1148, 2013
962013
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