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Tony K.T. Lam
Tony K.T. Lam
Toronto General Hospital Research Institute & University of Toronto
Verified email at uhnresearch.ca
Title
Cited by
Cited by
Year
Hypothalamic KATP channels control hepatic glucose production
A Pocai, TKT Lam, R Gutierrez-Juarez, S Obici, GJ Schwartz, J Bryan, ...
Nature 434 (7036), 1026-1031, 2005
7872005
The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species
Y Lin, AH Berg, P Iyengar, TKT Lam, A Giacca, TP Combs, MW Rajala, ...
Journal of biological chemistry 280 (6), 4617-4626, 2005
6812005
Hypothalamic sensing of fatty acids
TKT Lam, GJ Schwartz, L Rossetti
Nature neuroscience 8 (5), 579-584, 2005
5412005
Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis
TKT Lam, A Pocai, R Gutierrez-Juarez, S Obici, J Bryan, L Aguilar-Bryan, ...
Nature medicine 11 (3), 320-327, 2005
5012005
Mechanisms of the free fatty acid-induced increase in hepatic glucose production
TKT Lam, A Carpentier, GF Lewis, G van de Werve, IG Fantus, A Giacca
American Journal of Physiology-Endocrinology and Metabolism 284 (5), E863-E873, 2003
4092003
Regulation of blood glucose by hypothalamic pyruvate metabolism
TKT Lam, R Gutierrez-Juarez, A Pocai, L Rossetti
Science 309 (5736), 943-947, 2005
4042005
Metformin activates a duodenal Ampk–dependent pathway to lower hepatic glucose production in rats
FA Duca, CD Côté, BA Rasmussen, M Zadeh-Tahmasebi, GA Rutter, ...
Nature medicine 21 (5), 506-511, 2015
3972015
Upper intestinal lipids trigger a gut–brain–liver axis to regulate glucose production
PYT Wang, L Caspi, CKL Lam, M Chari, X Li, PE Light, R Gutierrez-Juarez, ...
Nature 452 (7190), 1012-1016, 2008
3682008
Regulation of obesity-related insulin resistance with gut anti-inflammatory agents
H Luck, S Tsai, J Chung, X Clemente-Casares, M Ghazarian, XS Revelo, ...
Cell metabolism 21 (4), 527-542, 2015
3582015
N-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible role of oxidative stress
CA Haber, TKT Lam, Z Yu, N Gupta, T Goh, E Bogdanovic, A Giacca, ...
American Journal of Physiology-Endocrinology and Metabolism 285 (4), E744-E753, 2003
3362003
Free fatty acid-induced hepatic insulin resistance: a potential role for protein kinase C-δ
TKT Lam, H Yoshii, CA Haber, E Bogdanovic, L Lam, IG Fantus, A Giacca
American Journal of Physiology-Endocrinology and Metabolism 283 (4), E682-E691, 2002
2792002
Molecular disruption of hypothalamic nutrient sensing induces obesity
W He, TKT Lam, S Obici, L Rossetti
Nature neuroscience 9 (2), 227-233, 2006
2632006
Jejunal nutrient sensing is required for duodenal-jejunal bypass surgery to rapidly lower glucose concentrations in uncontrolled diabetes
DM Breen, BA Rasmussen, A Kokorovic, R Wang, GWC Cheung, ...
Nature medicine 18 (6), 950-955, 2012
2542012
Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats
A Pocai, TKT Lam, S Obici, R Gutierrez-Juarez, ED Muse, A Arduini, ...
The Journal of clinical investigation 116 (4), 1081-1091, 2006
2532006
Metformin alters upper small intestinal microbiota that impact a glucose-SGLT1-sensing glucoregulatory pathway
PV Bauer, FA Duca, TMZ Waise, BA Rasmussen, MA Abraham, ...
Cell Metabolism 27 (1), 101-117. e5, 2018
2442018
Free fatty acids increase basal hepatic glucose production and induce hepatic insulin resistance at different sites
TKT Lam, G Van de Werve, A Giacca
American Journal of Physiology-Endocrinology And Metabolism 284 (2), E281-E290, 2003
2222003
Intestinal cholecystokinin controls glucose production through a neuronal network
GWC Cheung, A Kokorovic, CKL Lam, M Chari, TKT Lam
Cell metabolism 10 (2), 99-109, 2009
2042009
Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins
TKT Lam, R Gutierrez-Juarez, A Pocai, S Bhanot, P Tso, GJ Schwartz, ...
Nature medicine 13 (2), 171-180, 2007
1732007
CNS regulation of glucose homeostasis
CKL Lam, M Chari, TKT Lam
Physiology 24 (3), 159-170, 2009
1582009
Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network
CD Côté, BA Rasmussen, FA Duca, M Zadeh-Tahmasebi, JA Baur, ...
Nature medicine 21 (5), 498-505, 2015
1522015
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