APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells E Belnoue, M Pihlgren, TL McGaha, C Tougne, AF Rochat, C Bossen, ... Blood, The Journal of the American Society of Hematology 111 (5), 2755-2764, 2008 | 425 | 2008 |
TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE M Ehlers, H Fukuyama, TL McGaha, A Aderem, JV Ravetch The Journal of experimental medicine 203 (3), 553, 2006 | 414 | 2006 |
Type I interferon in chronic virus infection and cancer LM Snell, TL McGaha, DG Brooks Trends in immunology 38 (8), 542-557, 2017 | 382 | 2017 |
Restoration of tolerance in lupus by targeted inhibitory receptor expression TL McGaha, B Sorrentino, JV Ravetch Science 307 (5709), 590, 2005 | 324 | 2005 |
Marginal zone macrophages suppress innate and adaptive immunity to apoptotic cells in the spleen TL McGaha, Y Chen, B Ravishankar, N van Rooijen, MCI Karlsson Blood 117 (20), 5403, 2011 | 227 | 2011 |
Tolerance to apoptotic cells is regulated by indoleamine 2, 3-dioxygenase B Ravishankar, H Liu, R Shinde, P Chandler, B Baban, M Tanaka, ... Proceedings of the National Academy of Sciences, 2012 | 208 | 2012 |
The aryl hydrocarbon receptor: connecting immunity to the microenvironment R Shinde, TL McGaha Trends in immunology 39 (12), 1005-1020, 2018 | 205 | 2018 |
Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity K Hezaveh, RS Shinde, A Klötgen, MJ Halaby, S Lamorte, R Quevedo, ... Immunity 55 (2), 324-340. e8, 2022 | 204 | 2022 |
Halofuginone, an inhibitor of type-I collagen synthesis and skin sclerosis, blocks transforming-growth-factor-β-mediated Smad3 activation in fibroblasts TL McGaha, C Bona, RG Phelps, H Spiera Journal of investigative dermatology 118 (3), 461-470, 2002 | 204 | 2002 |
Amino acid catabolism: a pivotal regulator of innate and adaptive immunity TL McGaha, L Huang, H Lemos, R Metz, M Mautino, GC Prendergast, ... Immunological reviews 249 (1), 135-157, 2012 | 202 | 2012 |
The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment MD Sharma, R Shinde, TL McGaha, L Huang, RB Holmgaard, ... Science advances 1 (10), e1500845, 2015 | 172 | 2015 |
Validation of CyTOF against flow cytometry for immunological studies and monitoring of human cancer clinical trials R Gadalla, B Noamani, BL MacLeod, RJ Dickson, M Guo, W Xu, ... Frontiers in oncology 9, 415, 2019 | 163 | 2019 |
Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1 C Roux, SM Jafari, R Shinde, G Duncan, DW Cescon, J Silvester, MF Chu, ... Proceedings of the National Academy of Sciences 116 (10), 4326-4335, 2019 | 156 | 2019 |
The amino acid sensor GCN2 inhibits inflammatory responses to apoptotic cells promoting tolerance and suppressing systemic autoimmunity B Ravishankar, H Liu, R Shinde, K Chaudhary, W Xiao, J Bradley, ... Proceedings of the National Academy of Sciences 112 (34), 10774-10779, 2015 | 151 | 2015 |
Apoptotic cell–induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans R Shinde, K Hezaveh, MJ Halaby, A Kloetgen, A Chakravarthy, ... Nature immunology 19 (6), 571-582, 2018 | 145 | 2018 |
Lack of skin fibrosis in tight skin (TSK) mice with targeted mutation in the interleukin-4Rα and transforming growth factor-β genes T McGaha, S Saito, RG Phelps, R Gordon, N Noben-Trauth, WE Paul, ... Journal of Investigative Dermatology 116 (1), 136-143, 2001 | 137 | 2001 |
Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-β production by fibroblasts T Kodera, TL McGaha, R Phelps, WE Paul, CA Bona Proceedings of the National Academy of Sciences 99 (6), 3800-3805, 2002 | 133 | 2002 |
Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells induces potent tolerogenic responses L Huang, L Li, H Lemos, PR Chandler, G Pacholczyk, B Baban, ... The Journal of Immunology 191 (7), 3509-3513, 2013 | 129 | 2013 |
An essential role of Ffar2 (Gpr43) in dietary fibre-mediated promotion of healthy composition of gut microbiota and suppression of intestinal carcinogenesis S Sivaprakasam, A Gurav, AV Paschall, GL Coe, K Chaudhary, Y Cai, ... Oncogenesis 5 (6), e238-e238, 2016 | 126 | 2016 |
Molecular aspects of regulation of collagen gene expression in fibrosis RK Bhogal, CM Stoica, TL McGaha, CA Bona Journal of clinical immunology 25, 592-603, 2005 | 109 | 2005 |