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Nikhil Vad
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Pharmacologic screens reveal metformin that suppresses GRP78-dependent autophagy to enhance the anti-myeloma effect of bortezomib
S Jagannathan, MAY Abdel-Malek, E Malek, N Vad, T Latif, KC Anderson, ...
Leukemia 29 (11), 2184-2191, 2015
1152015
MiR-29b replacement inhibits proteasomes and disrupts aggresome+ autophagosome formation to enhance the antimyeloma benefit of bortezomib
S Jagannathan, N Vad, S Vallabhapurapu, KC Anderson, JJ Driscoll
Leukemia 29 (3), 727-738, 2015
782015
Efficacy of caffeic acid phenethyl ester (CAPE) in skin B16-F0 melanoma tumor bearing C57BL/6 mice
SK Kudugunti, NM Vad, E Ekogbo, MY Moridani
Investigational new drugs 29, 52-62, 2011
712011
Biochemical mechanism of caffeic acid phenylethyl ester (CAPE) selective toxicity towards melanoma cell lines
SK Kudugunti, NM Vad, AJ Whiteside, BU Naik, MA Yusuf, ...
Chemico-biological interactions 188 (1), 1-14, 2010
542010
Pharmacogenomics and chemical library screens reveal a novel SCFSKP2 inhibitor that overcomes Bortezomib resistance in multiple myeloma
E Malek, MAY Abdel-Malek, S Jagannathan, N Vad, R Karns, AG Jegga, ...
Leukemia 31 (3), 645-653, 2017
532017
Biochemical mechanism of acetaminophen (APAP) induced toxicity in melanoma cell lines
NM Vad, G Yount, D Moore, J Weidanz, MY Moridani
Journal of pharmaceutical sciences 98 (4), 1409-1425, 2009
412009
Biochemical mechanism of acetylsalicylic acid (Aspirin) selective toxicity toward melanoma cell lines
NM Vad, G Yount, MY Moridani
Melanoma Research 18 (6), 386-399, 2008
342008
Efficacy of acetylsalicylic acid (aspirin) in skin B16-F0 melanoma tumor-bearing C57BL/6 mice
MMY Vad NM, Kudugunti SK, Wang H, Bhat GJ
Tumour Biol. 35 (5), 4967-76, 2014
25*2014
Efficacy of acetylsalicylic acid (aspirin) in skin B16-F0 melanoma tumor-bearing C57BL/6 mice
NM Vad, SK Kudugunti, H Wang, GJ Bhat, MY Moridani
Tumor Biology 35, 4967-4976, 2014
252014
Structure–toxicity relationship of phenolic analogs as anti-melanoma agents: An enzyme directed prodrug approach
NM Vad, PK Kandala, SK Srivastava, MY Moridani
Chemico-biological interactions 183 (3), 462-471, 2010
182010
Efficacy of acetaminophen in skin B16-F0 melanoma tumor-bearing C57BL/6 mice
NM Vad, SK Kudugunti, D Graber, N Bailey, K Srivenugopal, MY Moridani
International journal of oncology 35 (1), 193-204, 2009
162009
Metabolic bioactivation and toxicity of ethyl 4-hydroxybenzoate in human SK-MEL-28 melanoma cells
NM Vad, IH Shaik, R Mehvar, MY Moridani
Journal of Pharmaceutical Sciences 97 (5), 1934-1945, 2008
162008
Abstract# 678: Biochemical mechanism of rutin toxicity in SK-MEL-28 melanoma cells: A tyrosinase bioactivation prodrug approach
N Vad, B Naik, M Moridani
Cancer Research 69 (9_Supplement), 678-678, 2009
22009
Mobilization of innate and adaptive antitumor immune responses by the RNP-targeting antibody ATRC-101
A Scholz, J DeFalco, Y Leung, IT Aydin, CJ Czupalla, W Cao, D Santos, ...
Proceedings of the National Academy of Sciences 119 (19), e2123483119, 2022
12022
Metformin suppresses GRP78-dependent PI3-Kinase activity in clonogenic side population to enhance the anti-myeloma benefit of bortezomib
JJ Driscoll, S Jagannathan, MAY Abdel Malek, N Vad, E Malek
Cancer Research 75 (15_Supplement), 4242-4242, 2015
12015
Long non-coding RNAs deregulated in Multiple Myeloma impact therapeutic response to proteasome inhibitors
E Malek, R Karns, AG Jegga, S Jagannathan, N Vad, MAY Abdel Malek, ...
Cancer Research 75 (15_Supplement), 153-153, 2015
12015
TM-03THE HSP90 INHIBITOR GANETESPIB IS AN EFFECTIVE THERAPY FOR GLIOBLASTOMA THAT BLOCKS EGFR-DRIVEN TUMOR GROWTH
J Driscoll, N Vad, S Jagannathan
Neuro-Oncology 16 (Suppl 5), v213, 2014
12014
SC-31RATIONAL DESIGN OF A PI3-KINASE/mTOR INHIBITOR CYTOTOXIC TO BRAIN CANCER STEM CELLS UNDER HYPOXIA
N Vad, S Jagannathan, K Sumita, M Abdel-Malek, J Driscoll
Neuro-Oncology 16 (Suppl 5), v203, 2014
12014
Antibodies that bind tumor tissue for diagnosis and therapy
J DeFalco, DE Emerling, J Finn, NM Greenberg, V Huang, SM Lippow, ...
US Patent App. 17/935,152, 2023
2023
1194 Discovery and pre-clinical development of a novel and differentiated EphA2-targeted antibody in multiple bispecific formats
M Bhatti, M Weiss, A Haltom, J Finn, A Gai, A Ye, D Zhang, C Czupalla, ...
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
2022
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