Bruce Verchere
Bruce Verchere
Professor of Medicine University of British Columbia and Child & Family Research Institute
Verified email at mail.ubc.ca - Homepage
TitleCited byYear
Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes.
SE Kahn, S Andrikopoulos, CB Verchere
Diabetes 48 (2), 241-253, 1999
5071999
β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment
LR Brunham, JK Kruit, TD Pape, JM Timmins, AQ Reuwer, Z Vasanji, ...
Nature medicine 13 (3), 340, 2007
3342007
Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide
CB Verchere, DA D'Alessio, RD Palmiter, GC Weir, S Bonner-Weir, ...
Proceedings of the National Academy of Sciences 93 (8), 3492-3496, 1996
2771996
Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood
JD Trudeau, C Kelly-Smith, CB Verchere, JF Elliott, JP Dutz, DT Finegood, ...
The Journal of clinical investigation 111 (2), 217-223, 2003
2582003
The flavanol (−)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP …
F Meng, A Abedini, A Plesner, CB Verchere, DP Raleigh
Biochemistry 49 (37), 8127-8133, 2010
1982010
Islet amyloid polypeptide and type 2 diabetes
L Marzban, K Park, CB Verchere
Experimental gerontology 38 (4), 347-351, 2003
1472003
Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence?
S Zraika, RL Hull, CB Verchere, A Clark, KJ Potter, PE Fraser, DP Raleigh, ...
Diabetologia 53 (6), 1046-1056, 2010
1422010
IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction
C Westwell-Roper, DL Dai, G Soukhatcheva, KJ Potter, N van Rooijen, ...
The journal of immunology 187 (5), 2755-2765, 2011
1412011
A multi-year analysis of islet transplantation compared with intensive medical therapy on progression of complications in type 1 diabetes
GL Warnock, DM Thompson, RM Meloche, RJ Shapiro, Z Ao, P Keown, ...
Transplantation 86 (12), 1762-1766, 2008
1372008
Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts
KJ Potter, A Abedini, P Marek, AM Klimek, S Butterworth, M Driscoll, ...
Proceedings of the National Academy of Sciences 107 (9), 4305-4310, 2010
1362010
Different effects of FK506, rapamycin, and mycophenolate mofetil on glucose-stimulated insulin release and apoptosis in human islets
JD Johnson, Z Ao, P Ao, H Li, LJ Dai, Z He, M Tee, KJ Potter, AM Klimek, ...
Cell transplantation 18 (8), 833-845, 2009
1342009
miR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets
N Wijesekara, L Zhang, MH Kang, T Abraham, A Bhattacharjee, ...
Diabetes 61 (3), 653-658, 2012
1202012
Cholesterol in islet dysfunction and type 2 diabetes
LR Brunham, JK Kruit, CB Verchere, MR Hayden
The Journal of clinical investigation 118 (2), 403-408, 2008
1192008
HDL and LDL cholesterol significantly influence β-cell function in type 2 diabetes mellitus
JK Kruit, LR Brunham, CB Verchere, MR Hayden
Current opinion in lipidology 21 (3), 178-185, 2010
1132010
Increased dietary fat promotes islet amyloid formation and β-cell secretory dysfunction in a transgenic mouse model of islet amyloid
RL Hull, S Andrikopoulos, CB Verchere, J Vidal, F Wang, M Cnop, ...
Diabetes 52 (2), 372-379, 2003
1102003
Recognition of HLA class I–restricted β-cell epitopes in type 1 diabetes
Q Ouyang, NE Standifer, H Qin, P Gottlieb, CB Verchere, GT Nepom, ...
Diabetes 55 (11), 3068-3074, 2006
1092006
Identification of novel HLA-A* 0201–restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives
NE Standifer, Q Ouyang, C Panagiotopoulos, CB Verchere, R Tan, ...
Diabetes 55 (11), 3061-3067, 2006
1082006
Moderate exercise attenuates caspase-3 activity, oxidative stress, and inhibits progression of diabetic renal disease in db/db mice
S Ghosh, M Khazaei, F Moien-Afshari, LS Ang, DJ Granville, CB Verchere, ...
American Journal of Physiology-Renal Physiology 296 (4), F700-F708, 2009
1072009
The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site
J Wang, J Xu, J Finnerty, M Furuta, DF Steiner, CB Verchere
Diabetes 50 (3), 534-539, 2001
1072001
Identification of a Heparin Binding Domain in the N-terminal Cleavage Site of Pro-islet Amyloid Polypeptide IMPLICATIONS FOR ISLET AMYLOID FORMATION
K Park, CB Verchere
Journal of Biological Chemistry 276 (20), 16611-16616, 2001
1062001
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