| Differential IκB kinase activation and IκBα degradation by interleukin-1β and tumor necrosis factor-α in human U937 monocytic cells: Evidence for additional regulatory steps in … Y Nasuhara, IM Adcock, M Catley, PJ Barnes, R Newton Journal of Biological Chemistry 274 (28), 19965-19972, 1999 | 186* | 1999 |
| Iκ-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma MA Birrell, E Hardaker, S Wong, K McCluskie, M Catley, J De Alba, ... American journal of respiratory and critical care medicine 172 (8), 962-971, 2005 | 179 | 2005 |
| Impact of tobacco‐smoke on key signaling pathways in the innate immune response in lung macrophages MA Birrell, S Wong, MC Catley, MG Belvisi Journal of cellular physiology 214 (1), 27-37, 2008 | 158 | 2008 |
| P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke S Eltom, CS Stevenson, J Rastrick, N Dale, K Raemdonck, S Wong, ... PLoS one 6 (9), e24097, 2011 | 145 | 2011 |
| Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IκB kinase inhibitors R Newton, NS Holden, MC Catley, W Oyelusi, R Leigh, D Proud, ... Journal of Pharmacology and Experimental Therapeutics 321 (2), 734-742, 2007 | 139 | 2007 |
| IL-1β-dependent activation of NF-κB mediates PGE2 release via the expression of cyclooxygenase-2 and microsomal prostaglandin E synthase MC Catley, JE Chivers, LM Cambridge, N Holden, DM Slater, KJ Staples, ... FEBS letters 547 (1-3), 75-79, 2003 | 136 | 2003 |
| Research in progress: medical research council united kingdom refractory asthma stratification programme (RASP-UK) LG Heaney, R Djukanovic, A Woodcock, S Walker, JG Matthews, ... Thorax 71 (2), 187-189, 2016 | 102 | 2016 |
| Inhibitors of protein kinase C (PKC) prevent activated transcription: role of events downstream of NF-κB DNA binding MC Catley, LM Cambridge, Y Nasuhara, K Ito, JE Chivers, A Beaton, ... Journal of Biological Chemistry 279 (18), 18457-18466, 2004 | 101 | 2004 |
| Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG … B Smith, A Kiessling, R Lledo-Garcia, KL Dixon, L Christodoulou, ... MAbs 10 (7), 1111-1130, 2018 | 94 | 2018 |
| Monoclonal antibodies for the treatment of asthma MC Catley, J Coote, M Bari, KL Tomlinson Pharmacology & therapeutics 132 (3), 333-351, 2011 | 93 | 2011 |
| Validation of the anti-inflammatory properties of small-molecule IκB kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative IKK1 and … MC Catley, MB Sukkar, KF Chung, B Jaffee, SM Liao, AJ Coyle, ... Molecular Pharmacology 70 (2), 697-705, 2006 | 87 | 2006 |
| Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses MA Birrell, MC Catley, E Hardaker, S Wong, TM Willson, K McCluskie, ... Journal of biological chemistry 282 (44), 31882-31890, 2007 | 77 | 2007 |
| IκB kinase-2-independent and-dependent inflammation in airway disease models: relevance of IKK-2 inhibition to the clinic MA Birrell, S Wong, EL Hardaker, MC Catley, K McCluskie, M Collins, ... Molecular pharmacology 69 (6), 1791-1800, 2006 | 73 | 2006 |
| IκB kinase-2-independent and-dependent inflammation in airway disease models: relevance of IKK-2 inhibition to the clinic MA Birrell, S Wong, EL Hardaker, MC Catley, K McCluskie, M Collins, ... Molecular pharmacology 69 (6), 1791-1800, 2006 | 73 | 2006 |
| ICAM‐1 expression is highly NF‐κB‐dependent in A549 cells: No role for ERK and p38 MAPK NS Holden, MC Catley, LM Cambridge, PJ Barnes, R Newton European journal of biochemistry 271 (4), 785-791, 2004 | 71 | 2004 |
| Inhibitors of JAK-family kinases: an update on the patent literature 2013-2015, part 1 JG Kettle, A Åstrand, M Catley, NP Grimster, M Nilsson, Q Su, R Woessner Expert Opinion on Therapeutic Patents 27 (2), 127-143, 2017 | 67 | 2017 |
| Increased levels of soluble interleukin-6 receptor and CCL3 in COPD sputum AK Ravi, S Khurana, J Lemon, J Plumb, G Booth, L Healy, M Catley, ... Respiratory research 15, 1-10, 2014 | 64 | 2014 |
| Cigarette smoke induced airway inflammation is independent of NF-κB signalling JMD Rastrick, CS Stevenson, S Eltom, M Grace, M Davies, I Kilty, ... PloS one 8 (1), e54128, 2013 | 64 | 2013 |
| Validation of IKKβ as therapeutic target in airway inflammatory disease by adenoviral‐mediated delivery of dominant‐negative IKKβ to pulmonary epithelial cells MC Catley, JE Chivers, NS Holden, PJ Barnes, R Newton British journal of pharmacology 145 (1), 114-122, 2005 | 62 | 2005 |
| Differential effects of RU486 reveal distinct mechanisms for glucocorticoid repression of prostaglandin E2 release JE Chivers, LM Cambridge, MC Catley, JC Mak, LE Donnelly, PJ Barnes, ... European journal of biochemistry 271 (20), 4042-4052, 2004 | 62 | 2004 |
Robert NewtonUniversity of CalgaryVerified email at ucalgary.ca
