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Janet R. Sparrow
Janet R. Sparrow
Anthony Donn Professor, Columbia University Medical Center
Verified email at cumc.columbia.edu
Title
Cited by
Cited by
Year
The lipofuscin fluorophore A2E mediates blue light–induced damage to retinal pigmented epithelial cells
JR Sparrow, K Nakanishi, CA Parish
Investigative ophthalmology & visual science 41 (7), 1981-1989, 2000
7772000
RPE lipofuscin and its role in retinal pathobiology
JR Sparrow, M Boulton
Experimental eye research 80 (5), 595-606, 2005
7682005
Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium
CA Parish, M Hashimoto, K Nakanishi, J Dillon, J Sparrow
Proceedings of the National Academy of Sciences 95 (25), 14609-14613, 1998
5471998
Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium
J Zhou, YP Jang, SR Kim, JR Sparrow
Proceedings of the National Academy of Sciences 103 (44), 16182-16187, 2006
4412006
Involvement of oxidative mechanisms in blue-light-induced damage to A2E-laden RPE
JR Sparrow, J Zhou, S Ben-Shabat, H Vollmer, Y Itagaki, K Nakanishi
Investigative ophthalmology & visual science 43 (4), 1222-1227, 2002
4092002
A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture
JR Sparrow, CA Parish, M Hashimoto, K Nakanishi
Investigative ophthalmology & visual science 40 (12), 2988-2995, 1999
4001999
The bisretinoids of retinal pigment epithelium
JR Sparrow, E Gregory-Roberts, K Yamamoto, A Blonska, SK Ghosh, ...
Progress in retinal and eye research 31 (2), 121-135, 2012
3842012
Blue light–induced apoptosis of A2E-containing RPE: involvement of caspase-3 and protection by Bcl-2
JR Sparrow, B Cai
Investigative ophthalmology & visual science 42 (6), 1356-1362, 2001
3632001
The susceptibility of the retina to photochemical damage from visible light
JJ Hunter, JIW Morgan, WH Merigan, DH Sliney, JR Sparrow, ...
Progress in retinal and eye research 31 (1), 28-42, 2012
3602012
Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice
M Allocca, M Doria, M Petrillo, P Colella, M Garcia-Hoyos, D Gibbs, ...
The Journal of clinical investigation 118 (5), 1955-1964, 2008
3522008
CD36 participates in the phagocytosis of rod outer segments by retinal pigment epithelium
SW Ryeom, JR Sparrow, RL Silverstein
Journal of cell science 109 (2), 387-395, 1996
3061996
Blue light-absorbing intraocular lens and retinal pigment epithelium protection in vitro
JR Sparrow, AS Miller, J Zhou
Journal of Cataract & Refractive Surgery 30 (4), 873-878, 2004
2952004
The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane
J Liu, Y Itagaki, S Ben-Shabat, K Nakanishi, JR Sparrow
Journal of Biological Chemistry 275 (38), 29354-29360, 2000
2902000
SOD2 knockdown mouse model of early AMD
V Justilien, JJ Pang, K Renganathan, X Zhan, JW Crabb, SR Kim, ...
Investigative ophthalmology & visual science 48 (10), 4407-4420, 2007
2732007
Correction of the disease phenotype in the mouse model of Stargardt disease by lentiviral gene therapy
J Kong, SR Kim, K Binley, I Pata, J Mannik, J Zernant-Rajang, O Kan, ...
Gene therapy 15 (19), 1311-1320, 2008
2622008
Photooxidation of A2-PE, a photoreceptor outer segment fluorophore, and protection by lutein and zeaxanthin
SR Kim, K Nakanishi, Y Itagaki, JR Sparrow
Experimental eye research 82 (5), 828-839, 2006
2612006
Lutein and zeaxanthin supplementation reduces photooxidative damage and modulates the expression of inflammation-related genes in retinal pigment epithelial cells
Q Bian, S Gao, J Zhou, J Qin, A Taylor, EJ Johnson, G Tang, JR Sparrow, ...
Free Radical Biology and Medicine 53 (6), 1298-1307, 2012
2572012
Biosynthetic studies of A2E, a major fluorophore of retinal pigment epithelial lipofuscin
S Ben-Shabat, CA Parish, HR Vollmer, Y Itagaki, N Fishkin, K Nakanishi, ...
Journal of Biological Chemistry 277 (9), 7183-7190, 2002
2562002
Experimental studies of tolerance to intravitreal perfluoro-n-octane liquid
S Chang, JR SPARROW, T IWAMOTO, A GERSHBEIN, R ROSS, R ORTIZ
Retina 11 (4), 367-374, 1991
2401991
Quantitative measurements of autofluorescence with the scanning laser ophthalmoscope
F Delori, JP Greenberg, RL Woods, J Fischer, T Duncker, J Sparrow, ...
Investigative ophthalmology & visual science 52 (13), 9379-9390, 2011
2372011
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