| A human colon cancer cell capable of initiating tumour growth in immunodeficient mice CA O’Brien, A Pollett, S Gallinger, JE Dick Nature 445 (7123), 106-110, 2007 | 5072 | 2007 |
| Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical … MJ Moore, D Goldstein, J Hamm, A Figer, JR Hecht, S Gallinger, HJ Au, ... Journal of clinical oncology 25 (15), 1960-1966, 2007 | 4719 | 2007 |
| Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer CM Ribic, DJ Sargent, MJ Moore, SN Thibodeau, AJ French, ... New England Journal of Medicine 349 (3), 247-257, 2003 | 2603 | 2003 |
| International network of cancer genome projects Data coordination centre Kasprzyk (Leader) Arek 1 Stein (Leader) Lincoln D ... Nature 464 (7291), 993-998, 2010 | 2143 | 2010 |
| Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes AV Biankin, N Waddell, KS Kassahn, MC Gingras, LB Muthuswamy, ... Nature 491 (7424), 399-405, 2012 | 2047 | 2012 |
| Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer DJ Sargent, S Marsoni, G Monges, SN Thibodeau, R Labianca, ... Journal of clinical oncology 28 (20), 3219-3226, 2010 | 1650 | 2010 |
| Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer R Gryfe, H Kim, ETK Hsieh, MD Aronson, EJ Holowaty, SB Bull, ... New England Journal of Medicine 342 (2), 69-77, 2000 | 1630 | 2000 |
| Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial JP Neoptolemos, DD Stocken, C Bassi, P Ghaneh, D Cunningham, ... Jama 304 (10), 1073-1081, 2010 | 1518 | 2010 |
| Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray Y Chen, M Lemire, S Choufani, DT Butcher, D Grafodatskaya, BW Zanke, ... Epigenetics 8 (2), 203-209, 2013 | 1417 | 2013 |
| MADR2 maps to 18q21 and encodes a TGFβ–regulated MAD–related protein that is functionally mutated in colorectal carcinoma K Eppert, SW Scherer, H Ozcelik, R Pirone, P Hoodless, H Kim, LC Tsui, ... Cell 86 (4), 543-552, 1996 | 1107 | 1996 |
| Convergence of genes and cellular pathways dysregulated in autism spectrum disorders D Pinto, E Delaby, D Merico, M Barbosa, A Merikangas, L Klei, ... The American Journal of Human Genetics 94 (5), 677-694, 2014 | 1009 | 2014 |
| Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors NM Lindor, LJ Burgart, O Leontovich, RM Goldberg, JM Cunningham, ... Journal of clinical oncology 20 (4), 1043-1048, 2002 | 948 | 2002 |
| Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24 BW Zanke, CMT Greenwood, J Rangrej, R Kustra, A Tenesa, ... Nature genetics 39 (8), 989-994, 2007 | 811 | 2007 |
| Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer A Kreso, CA O'Brien, P Van Galen, OI Gan, F Notta, AMK Brown, K Ng, ... Science 339 (6119), 543-548, 2013 | 791 | 2013 |
| Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer L Amundadottir, P Kraft, RZ Stolzenberg-Solomon, CS Fuchs, ... Nature genetics 41 (9), 986-990, 2009 | 722 | 2009 |
| Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X NM Lindor, K Rabe, GM Petersen, R Haile, G Casey, J Baron, S Gallinger, ... Jama 293 (16), 1979-1985, 2005 | 676 | 2005 |
| Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21 A Tenesa, SM Farrington, JGD Prendergast, ME Porteous, M Walker, ... Nature genetics 40 (5), 631-637, 2008 | 668 | 2008 |
| Organoid profiling identifies common responders to chemotherapy in pancreatic cancerpancreatic cancer organoids parallel patient response H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... Cancer discovery 8 (9), 1112-1129, 2018 | 649 | 2018 |
| CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer H Ling, R Spizzo, Y Atlasi, M Nicoloso, M Shimizu, RS Redis, N Nishida, ... Genome research 23 (9), 1446-1461, 2013 | 639 | 2013 |
| Hereditary diffuse gastric cancer syndrome: CDH1 mutations and beyond S Hansford, P Kaurah, H Li-Chang, M Woo, J Senz, H Pinheiro, ... JAMA oncology 1 (1), 23-32, 2015 | 636 | 2015 |
