Alberto Lleo
Alberto Lleo
Memory Disorders Unit Head, Neurology Department. Hospital Sant Pau. Barcelona.
Verified email at santpau.es - Homepage
TitleCited byYear
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ...
Nature genetics 45 (12), 1452, 2013
19542013
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis
WJ Jansen, R Ossenkoppele, DL Knol, BM Tijms, P Scheltens, ...
Jama 313 (19), 1924-1938, 2015
5692015
Current pharmacotherapy for Alzheimer's disease
A Lleo, SM Greenberg, JH Growdon
Annu. Rev. Med. 57, 513-533, 2006
3542006
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
G Kleinberger, Y Yamanishi, M Suárez-Calvet, E Czirr, E Lohmann, ...
Science translational medicine 6 (243), 243ra86-243ra86, 2014
3112014
Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis
R Ossenkoppele, WJ Jansen, GD Rabinovici, DL Knol, WM van der Flier, ...
Jama 313 (19), 1939-1950, 2015
2582015
A novel GSK-3β inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo
L Sereno, M Coma, M Rodriguez, P Sanchez-Ferrer, MB Sanchez, I Gich, ...
Neurobiology of disease 35 (3), 359-367, 2009
2442009
CSF biomarker variability in the Alzheimer's Association quality control program
N Mattsson, U Andreasson, S Persson, MC Carrillo, S Collins, S Chalbot, ...
Alzheimer's & Dementia 9 (3), 251-261, 2013
2402013
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373, 2017
2392017
Nonsteroidal anti-inflammatory drugs lower Aβ42 and change presenilin 1 conformation
A Lleó, O Berezovska, L Herl, S Raju, A Deng, BJ Bacskai, MP Frosch, ...
Nature medicine 10 (10), 1065, 2004
2392004
Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP
RJ Guerreiro, M Baquero, R Blesa, M Boada, JM Brás, MJ Bullido, ...
Neurobiology of aging 31 (5), 725-731, 2010
1712010
European Alzheimer’s Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer’s Disease; Alzheimer’s Disease Genetic Consortium; Cohorts for Heart and Aging …
JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ...
Nat Genet 45 (12), 1452-1458, 2013
1662013
Frontotemporal dementia and its subtypes: a genome-wide association study
R Ferrari, DG Hernandez, MA Nalls, JD Rohrer, A Ramasamy, JBJ Kwok, ...
The Lancet Neurology 13 (7), 686-699, 2014
1642014
Familial Alzheimer's disease presenilin 1 mutations cause alterations in the conformation of presenilin and interactions with amyloid precursor protein
O Berezovska, A Lleo, LD Herl, MP Frosch, EA Stern, BJ Bacskai, ...
Journal of Neuroscience 25 (11), 3009-3017, 2005
1522005
sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers
M Suárez‐Calvet, G Kleinberger, MÁA Caballero, M Brendel, A Rominger, ...
EMBO molecular medicine 8 (5), 466-476, 2016
1232016
Dementia risk in Parkinson disease: disentangling the role of MAPT haplotypes
N Setó-Salvia, J Clarimón, J Pagonabarraga, B Pascual-Sedano, ...
Archives of neurology 68 (3), 359-364, 2011
1152011
Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases
A Lleo, E Cavedo, L Parnetti, H Vanderstichele, SK Herukka, ...
Nature Reviews Neurology 11 (1), 41, 2015
1112015
A novel Alzheimer disease locus located near the gene encoding tau protein
G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ...
Molecular psychiatry 21 (1), 108, 2016
1102016
Low cerebrospinal fluid concentration of mitochondrial DNA in preclinical Alzheimer disease
P Podlesniy, J Figueiro‐Silva, A Llado, A Antonell, R Sanchez‐Valle, ...
Annals of neurology 74 (5), 655-668, 2013
1072013
Glucocerebrosidase mutations confer a greater risk of dementia during Parkinson's disease course
N Setó‐Salvia, J Pagonabarraga, H Houlden, B Pascual‐Sedano, ...
Movement Disorders 27 (3), 393-399, 2012
1072012
The proton-pump inhibitor lansoprazole enhances amyloid beta production
N Badiola, V Alcalde, A Pujol, LM Münter, G Multhaup, A Lleó, M Coma, ...
PloS one 8 (3), e58837, 2013
1022013
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