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Spyridon Theofilopoulos
Spyridon Theofilopoulos
Professor, Instructor, Deree-The American College of Greece, Biomedical Sciences
Verified email at acg.edu
Title
Cited by
Cited by
Year
Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells
P Sacchetti, KM Sousa, AC Hall, I Liste, KR Steffensen, S Theofilopoulos, ...
Cell stem cell 5 (4), 409-419, 2009
1722009
Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain?
M Ogundare, S Theofilopoulos, A Lockhart, LJ Hall, E Arenas, J Sjövall, ...
Journal of Biological Chemistry 285 (7), 4666-4679, 2010
1362010
Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis
S Theofilopoulos, Y Wang, SS Kitambi, P Sacchetti, KM Sousa, K Bodin, ...
Nature chemical biology 9 (2), 126-133, 2013
1302013
Cholestenoic acids regulate motor neuron survival via liver X receptors
S Theofilopoulos, WJ Griffiths, PJ Crick, S Yang, A Meljon, M Ogundare, ...
The Journal of clinical investigation 124 (11), 4829, 2014
1002014
The differentiation potential of human foetal neuronal progenitor cells in vitro
SS Riaz, S Theofilopoulos, E Jauniaux, GM Stern, HF Bradford
Developmental brain research 153 (1), 39-51, 2004
802004
Analysis of bioactive oxysterols in newborn mouse brain by LC/MS
A Meljon, S Theofilopoulos, CHL Shackleton, GL Watson, NB Javitt, ...
Journal of Lipid Research 53 (11), 2469-2483, 2012
612012
Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons.
L Čajánek, RS Ganji, C Henriques-Oliveira, S Theofilopoulos, P Koník, ...
Molecular and Cellular Biology, 2012
552012
The neuronal survival effects of rasagiline and deprenyl on fetal human and rat ventral mesencephalic neurones in culture
J Goggi, S Theofilopoulos, SS Riaz, E Jauniaux, GM Stern, HF Bradford
Neuroreport 11 (18), 3937-3941, 2000
532000
Parallel induction of the formation of dopamine and its metabolites with induction of tyrosine hydroxylase expression in foetal rat and human cerebral cortical cells by brain …
S Theofilopoulos, J Goggi, SS Riaz, E Jauniaux, GM Stern, HF Bradford
Developmental Brain Research 127 (2), 111-122, 2001
502001
Targeted lipidomic analysis of oxysterols in the embryonic central nervous system
Y Wang, KM Sousa, K Bodin, S Theofilopoulos, P Sacchetti, M Hornshaw, ...
Molecular bioSystems 5 (5), 529-541, 2009
482009
Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma
WJ Griffiths, PJ Crick, A Meljon, S Theofilopoulos, J Abdel-Khalik, E Yutuc, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019
382019
Dopamine receptor antagonists enhance proliferation and neurogenesis of midbrain Lmx1a-expressing progenitors
E Hedlund, L Belnoue, S Theofilopoulos, C Salto, C Bye, C Parish, ...
Scientific reports 6, 2016
382016
24(S),25-Epoxycholesterol and cholesterol 24S-hydroxylase (CYP46A1) overexpression promote midbrain dopaminergic neurogenesis in vivo
S Theofilopoulos, WAA de Oliveira, S Yang, E Yutuc, A Saeed, ...
Journal of Biological Chemistry, jbc. RA118. 005639, 2019
332019
Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis
D Ribeiro, K Ellwanger, D Glagow, S Theofilopoulos, NS Corsini, ...
PLoS One 6 (2), e15786, 2011
282011
The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation
D Gyllborg, M Ahmed, EM Toledo, S Theofilopoulos, S Yang, ...
Stem Cell Reports 11 (3), 651-664, 2018
262018
Liver X receptors and cholesterol metabolism: role in ventral midbrain development and neurodegeneration
S Theofilopoulos, E Arenas
F1000prime reports 7, 2015
212015
Mining for Oxysterols in Cyp7b1−/− Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5
A Meljon, PJ Crick, E Yutuc, J Yau L., JR Seckl, S Theofilopoulos, ...
Biomolecules 9 (4), 149, 2019
142019
12-O-tetradecanoyl-phorbol-13-acetate-dependent up-regulation of dopaminergic gene expression requires Ras and neurofibromin in human IMR-32 neuroblastoma
D Mangoura, S Theofilopoulos, S Karouzaki, E Tsirimonaki
JOURNAL OF NEUROCHEMISTRY 97 (S1), 97-103, 2006
142006
The cerebrospinal fluid profile of cholesterol metabolites in Parkinson’s disease and their association with disease state and clinical features
WJ Griffiths, J Abdel-Khalik, SF Moore, RS Wijeyekoon, PJ Crick, E Yutuc, ...
Frontiers in Aging Neuroscience 13 (685594), 2021
132021
Novel function of the human presqualene diphosphate phosphatase as a type II phosphatidate phosphatase in phosphatidylcholine and triacylglyceride biosynthesis pathways
S Theofilopoulos, A Lykidis, G Leondaritis, D Mangoura
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1781 (11 …, 2008
62008
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