Spyridon Theofilopoulos

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William J GriffithsSwansea UniversityVerified email at swansea.ac.uk
yuqin wangSwansea University Medical SchoolVerified email at swansea.ac.uk
Paola SacchettiAssociate Professor, Director Master Program in Neuroscience, Hartford UniversityVerified email at hartford.edu
Kyle M. SousaAssociate Dean, Academic Affairs & Associate Professor, Pharmaceutical SciencesVerified email at llu.edu
Jan-Ake GustafssonRobert A. Welch Professor, Department of Biology and Biochemistry, University of HoustonVerified email at central.uh.edu
Eric JauniauxProfessor in Obstetrics and Fetal medicineVerified email at ucl.ac.uk
Clare ParishFlorey Institute of Neuroscience and Mental Health, The University of MelbourneVerified email at unimelb.edu.au
Eylan YutucSwansea UniversityVerified email at swansea.ac.uk
Toledo EMNovo Nordisk Research Centre OxfordVerified email at novonordisk.com
Jonas Abdel - KhalikInstitute of Mass Spectrometry, Swansea UniversityVerified email at swansea.ac.uk
Dimitra MangouraBiomedical Research Foundation Academy of AthensVerified email at bioacademy.gr
Patrik ErnforsVerified email at ki.se
Shanzheng YangKarolinska InstituteVerified email at ki.se
Norman B JavittResearh Professor of Medicine and Pediatrics New York University-Grossman School of MedicineVerified email at nyulangone.org
Lukas CajanekMasaryk University, Faculty of Medicine, BrnoVerified email at med.muni.cz
Martin HornshawThermo Fisher ScientificVerified email at thermofisher.com
Chris ByeThe Florey Institute of Neuroscience & Mental HealthVerified email at florey.edu.au
Eva HedlundDepartment of Biochemistry and Biophysics, Stockholm UniversityVerified email at dbb.su.se
Qiaolin DengDept. Physiology and Pharmacology, Karolinska InstiutetVerified email at ki.se
Thomas PerlmannKarolinska InstitutetVerified email at ki.se

Spyridon Theofilopoulos

Sêr Cymru Rising Star fellow, Associate Professor, Institute of Life Science 1, Swansea University

Verified email at swansea.ac.uk - Homepage

Regenerative Neurobiology Lipid Biochemistry


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Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells P Sacchetti, KM Sousa, AC Hall, I Liste, KR Steffensen, S Theofilopoulos, ... Cell stem cell 5 (4), 409-419, 2009	150	2009
Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? M Ogundare, S Theofilopoulos, A Lockhart, LJ Hall, E Arenas, J Sjövall, ... Journal of Biological Chemistry 285 (7), 4666-4679, 2010	127	2010
Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis S Theofilopoulos, Y Wang, SS Kitambi, P Sacchetti, KM Sousa, K Bodin, ... Nature chemical biology 9 (2), 126-133, 2013	112	2013
Cholestenoic acids regulate motor neuron survival via liver X receptors S Theofilopoulos, WJ Griffiths, PJ Crick, S Yang, A Meljon, M Ogundare, ... The Journal of clinical investigation 124 (11), 4829, 2014	83	2014
The differentiation potential of human foetal neuronal progenitor cells in vitro SS Riaz, S Theofilopoulos, E Jauniaux, GM Stern, HF Bradford Developmental brain research 153 (1), 39-51, 2004	74	2004
Analysis of bioactive oxysterols in newborn mouse brain by LC/MS A Meljon, S Theofilopoulos, CHL Shackleton, GL Watson, NB Javitt, ... Journal of Lipid Research 53 (11), 2469-2483, 2012	53	2012
Parallel induction of the formation of dopamine and its metabolites with induction of tyrosine hydroxylase expression in foetal rat and human cerebral cortical cells by brain … S Theofilopoulos, J Goggi, SS Riaz, E Jauniaux, GM Stern, HF Bradford Developmental Brain Research 127 (2), 111-122, 2001	51	2001
The neuronal survival effects of rasagiline and deprenyl on fetal human and rat ventral mesencephalic neurones in culture J Goggi, S Theofilopoulos, SS Riaz, E Jauniaux, GM Stern, HF Bradford Neuroreport 11 (18), 3937-3941, 2000	50	2000
Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons. L Čajánek, RS Ganji, C Henriques-Oliveira, S Theofilopoulos, P Koník, ... Molecular and Cellular Biology, 2012	45	2012
Targeted lipidomic analysis of oxysterols in the embryonic central nervous system Y Wang, KM Sousa, K Bodin, S Theofilopoulos, P Sacchetti, M Hornshaw, ... Molecular bioSystems 5 (5), 529-541, 2009	41	2009
Dopamine receptor antagonists enhance proliferation and neurogenesis of midbrain Lmx1a-expressing progenitors E Hedlund, L Belnoue, S Theofilopoulos, C Salto, C Bye, C Parish, ... Scientific reports 6, 2016	32	2016
Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma WJ Griffiths, PJ Crick, A Meljon, S Theofilopoulos, J Abdel-Khalik, E Yutuc, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019	29	2019
Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis D Ribeiro, K Ellwanger, D Glagow, S Theofilopoulos, NS Corsini, ... PLoS One 6 (2), e15786, 2011	24	2011
24(S),25-Epoxycholesterol and cholesterol 24S-hydroxylase (CYP46A1) overexpression promote midbrain dopaminergic neurogenesis in vivo S Theofilopoulos, WAA de Oliveira, S Yang, E Yutuc, A Saeed, ... Journal of Biological Chemistry, jbc. RA118. 005639, 2019	22	2019
Liver X receptors and cholesterol metabolism: role in ventral midbrain development and neurodegeneration S Theofilopoulos, E Arenas F1000prime reports 7, 2015	15	2015
The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation D Gyllborg, M Ahmed, EM Toledo, S Theofilopoulos, S Yang, ... Stem Cell Reports 11 (3), 651-664, 2018	13	2018
12-O-tetradecanoyl-phorbol-13-acetate-dependent up-regulation of dopaminergic gene expression requires Ras and neurofibromin in human IMR-32 neuroblastoma D Mangoura, S Theofilopoulos, S Karouzaki, E Tsirimonaki JOURNAL OF NEUROCHEMISTRY 97 (S1), 97-103, 2006	13	2006
Mining for Oxysterols in Cyp7b1−/− Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5 A Meljon, PJ Crick, E Yutuc, J Yau L., JR Seckl, S Theofilopoulos, ... Biomolecules 9 (4), 149, 2019	10	2019
Novel function of the human presqualene diphosphate phosphatase as a type II phosphatidate phosphatase in phosphatidylcholine and triacylglyceride biosynthesis pathways S Theofilopoulos, A Lykidis, G Leondaritis, D Mangoura BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1781 (11 …, 2008	6	2008
DIFFERENTIAL PROPERTIES OF NEUROFIBROMIN GRDI AND II IN DEVELOPING NEURONS S Karouzaki, S Theofilopoulos, D Mangoura Journal of neurochemistry 118, 192-192, 2011	2	2011

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