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Vinit C. Shanbhag
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Copper metabolism as a unique vulnerability in cancer
VC Shanbhag, N Gudekar, K Jasmer, C Papageorgiou, K Singh, MJ Petris
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1868 (2), 118893, 2021
2322021
ATP7A delivers copper to the lysyl oxidase family of enzymes and promotes tumorigenesis and metastasis
V Shanbhag, K Jasmer-McDonald, S Zhu, AL Martin, N Gudekar, A Khan, ...
Proceedings of the National Academy of Sciences 116 (14), 6836-6841, 2019
1352019
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice
LM Guthrie, S Soma, S Yuan, A Silva, M Zulkifli, TC Snavely, HF Greene, ...
Science 368 (6491), 620-625, 2020
792020
Cu 2+ selective chelators relieve copper-induced oxidative stress in vivo
A Rakshit, K Khatua, V Shanbhag, P Comba, A Datta
Chemical Science 9 (41), 7916-7930, 2018
702018
Host and pathogen copper-transporting P-type ATPases function antagonistically during Salmonella infection
E Ladomersky, A Khan, V Shanbhag, JS Cavet, J Chan, GA Weisman, ...
Infection and immunity 85 (9), 10.1128/iai. 00351-17, 2017
662017
A role for the ATP7A copper transporter in tumorigenesis and cisplatin resistance
S Zhu, V Shanbhag, Y Wang, J Lee, M Petris
Journal of Cancer 8 (11), 1952, 2017
572017
Isolation, Characterization and Bioactivities of an Extracellular Polysaccharide Produced from Streptomyces sp. MOE6
MO Elnahas, MA Amin, MMD Hussein, VC Shanbhag, AE Ali, JD Wall
Molecules 22 (9), 1396, 2017
362017
Metallothioneins regulate ATP7A trafficking and control cell viability during copper deficiency and excess
N Gudekar, V Shanbhag, Y Wang, M Ralle, GA Weisman, MJ Petris
Scientific reports 10 (1), 7856, 2020
312020
P2Y receptors for extracellular nucleotides: Contributions to cancer progression and therapeutic implications
LT Woods, KM Forti, VC Shanbhag, JM Camden, GA Weisman
Biochemical pharmacology 187, 114406, 2021
292021
P2Y2 receptors mediate nucleotide-induced EGFR phosphorylation and stimulate proliferation and tumorigenesis of head and neck squamous cell carcinoma cell lines
LT Woods, KJ Jasmer, KM Forti, VC Shanbhag, JM Camden, L Erb, ...
Oral oncology 109, 104808, 2020
232020
FDX1-dependent and independent mechanisms of elesclomol-mediated intracellular copper delivery
M Zulkifli, AN Spelbring, Y Zhang, S Soma, S Chen, L Li, T Le, ...
Proceedings of the National Academy of Sciences 120 (10), e2216722120, 2023
222023
Multiple di-leucines in the ATP7A copper transporter are required for retrograde trafficking to the trans-Golgi network
S Zhu, V Shanbhag, VL Hodgkinson, MJ Petris
Metallomics 8 (9), 993-1001, 2016
142016
Family a and B DNA polymerases in Cancer: opportunities for therapeutic interventions
V Shanbhag, S Sachdev, JA Flores, MJ Modak, K Singh
Biology 7 (1), 5, 2018
112018
Ceruloplasmin as a source of Cu for a fungal pathogen
AN Besold, V Shanbhag, MJ Petris, VC Culotta
Journal of inorganic biochemistry 219, 111424, 2021
102021
APOE expression and secretion are modulated by mitochondrial dysfunction
ME Wynne, O Ogunbona, AR Lane, A Gokhale, SA Zlatic, C Xu, Z Wen, ...
Elife 12, e85779, 2023
82023
Regulation of Atp7a RNA contributes to differentiation-dependent Cu redistribution in skeletal muscle cells
TJ Whitlow, Y Zhang, N Ferguson, AM Perez, H Patel, JA Link-Kemp, ...
Metallomics 15 (7), mfad042, 2023
22023
Copper chelation reduces early collagen deposition and preserves saliva secretion in irradiated salivary glands
K Nam, HT Dos Santos, FM Maslow, T Small, V Shanbhag, MJ Petris, ...
Heliyon 10 (2), 2024
2024
APOE Expression and Secretion are Modulated by Copper-Dependent and-Independent Mitochondrial Dysfunction
ME Wynne, O Ogunbona, AR Lane, A Gokhale, S Zlatic, C Xu, Z Wen, ...
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