Copper metabolism as a unique vulnerability in cancer VC Shanbhag, N Gudekar, K Jasmer, C Papageorgiou, K Singh, MJ Petris Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1868 (2), 118893, 2021 | 232 | 2021 |
ATP7A delivers copper to the lysyl oxidase family of enzymes and promotes tumorigenesis and metastasis V Shanbhag, K Jasmer-McDonald, S Zhu, AL Martin, N Gudekar, A Khan, ... Proceedings of the National Academy of Sciences 116 (14), 6836-6841, 2019 | 135 | 2019 |
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice LM Guthrie, S Soma, S Yuan, A Silva, M Zulkifli, TC Snavely, HF Greene, ... Science 368 (6491), 620-625, 2020 | 79 | 2020 |
Cu 2+ selective chelators relieve copper-induced oxidative stress in vivo A Rakshit, K Khatua, V Shanbhag, P Comba, A Datta Chemical Science 9 (41), 7916-7930, 2018 | 70 | 2018 |
Host and pathogen copper-transporting P-type ATPases function antagonistically during Salmonella infection E Ladomersky, A Khan, V Shanbhag, JS Cavet, J Chan, GA Weisman, ... Infection and immunity 85 (9), 10.1128/iai. 00351-17, 2017 | 66 | 2017 |
A role for the ATP7A copper transporter in tumorigenesis and cisplatin resistance S Zhu, V Shanbhag, Y Wang, J Lee, M Petris Journal of Cancer 8 (11), 1952, 2017 | 57 | 2017 |
Isolation, Characterization and Bioactivities of an Extracellular Polysaccharide Produced from Streptomyces sp. MOE6 MO Elnahas, MA Amin, MMD Hussein, VC Shanbhag, AE Ali, JD Wall Molecules 22 (9), 1396, 2017 | 36 | 2017 |
Metallothioneins regulate ATP7A trafficking and control cell viability during copper deficiency and excess N Gudekar, V Shanbhag, Y Wang, M Ralle, GA Weisman, MJ Petris Scientific reports 10 (1), 7856, 2020 | 31 | 2020 |
P2Y receptors for extracellular nucleotides: Contributions to cancer progression and therapeutic implications LT Woods, KM Forti, VC Shanbhag, JM Camden, GA Weisman Biochemical pharmacology 187, 114406, 2021 | 29 | 2021 |
P2Y2 receptors mediate nucleotide-induced EGFR phosphorylation and stimulate proliferation and tumorigenesis of head and neck squamous cell carcinoma cell lines LT Woods, KJ Jasmer, KM Forti, VC Shanbhag, JM Camden, L Erb, ... Oral oncology 109, 104808, 2020 | 23 | 2020 |
FDX1-dependent and independent mechanisms of elesclomol-mediated intracellular copper delivery M Zulkifli, AN Spelbring, Y Zhang, S Soma, S Chen, L Li, T Le, ... Proceedings of the National Academy of Sciences 120 (10), e2216722120, 2023 | 22 | 2023 |
Multiple di-leucines in the ATP7A copper transporter are required for retrograde trafficking to the trans-Golgi network S Zhu, V Shanbhag, VL Hodgkinson, MJ Petris Metallomics 8 (9), 993-1001, 2016 | 14 | 2016 |
Family a and B DNA polymerases in Cancer: opportunities for therapeutic interventions V Shanbhag, S Sachdev, JA Flores, MJ Modak, K Singh Biology 7 (1), 5, 2018 | 11 | 2018 |
Ceruloplasmin as a source of Cu for a fungal pathogen AN Besold, V Shanbhag, MJ Petris, VC Culotta Journal of inorganic biochemistry 219, 111424, 2021 | 10 | 2021 |
APOE expression and secretion are modulated by mitochondrial dysfunction ME Wynne, O Ogunbona, AR Lane, A Gokhale, SA Zlatic, C Xu, Z Wen, ... Elife 12, e85779, 2023 | 8 | 2023 |
Regulation of Atp7a RNA contributes to differentiation-dependent Cu redistribution in skeletal muscle cells TJ Whitlow, Y Zhang, N Ferguson, AM Perez, H Patel, JA Link-Kemp, ... Metallomics 15 (7), mfad042, 2023 | 2 | 2023 |
Copper chelation reduces early collagen deposition and preserves saliva secretion in irradiated salivary glands K Nam, HT Dos Santos, FM Maslow, T Small, V Shanbhag, MJ Petris, ... Heliyon 10 (2), 2024 | | 2024 |
APOE Expression and Secretion are Modulated by Copper-Dependent and-Independent Mitochondrial Dysfunction ME Wynne, O Ogunbona, AR Lane, A Gokhale, S Zlatic, C Xu, Z Wen, ... | | |