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Alexander G Fletcher
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Vertex models of epithelial morphogenesis
AG Fletcher, M Osterfield, RE Baker, SY Shvartsman
Biophysical journal 106 (11), 2291-2304, 2014
5812014
Chaste: an open source C++ library for computational physiology and biology
GR Mirams, CJ Arthurs, MO Bernabeu, R Bordas, J Cooper, A Corrias, ...
PLoS computational biology 9 (3), e1002970, 2013
4952013
Chaste: a test-driven approach to software development for biological modelling
J Pitt-Francis, P Pathmanathan, MO Bernabeu, R Bordas, J Cooper, ...
Computer Physics Communications 180 (12), 2452-2471, 2009
2972009
Quantification of crypt and stem cell evolution in the normal and neoplastic human colon
AM Baker, B Cereser, S Melton, AG Fletcher, M Rodriguez-Justo, ...
Cell reports 8 (4), 940-947, 2014
2292014
Comparing individual-based approaches to modelling the self-organization of multicellular tissues
JM Osborne, AG Fletcher, JM Pitt-Francis, PK Maini, DJ Gavaghan
PLoS computational biology 13 (2), e1005387, 2017
2162017
An integrative computational model for intestinal tissue renewal
IMM Van Leeuwen, GR Mirams, A Walter, A Fletcher, P Murray, J Osborne, ...
Cell proliferation 42 (5), 617-636, 2009
1792009
Implementing vertex dynamics models of cell populations in biology within a consistent computational framework
AG Fletcher, JM Osborne, PK Maini, DJ Gavaghan
Progress in biophysics and molecular biology 113 (2), 299-326, 2013
1722013
Steering evolution with sequential therapy to prevent the emergence of bacterial antibiotic resistance
D Nichol, P Jeavons, AG Fletcher, RA Bonomo, PK Maini, JL Paul, ...
PLoS computational biology 11 (9), e1004493, 2015
1632015
A hybrid approach to multi-scale modelling of cancer
JM Osborne, A Walter, SK Kershaw, GR Mirams, AG Fletcher, ...
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2010
1512010
A computational study of discrete mechanical tissue models
P Pathmanathan, J Cooper, A Fletcher, G Mirams, P Murray, J Osborne, ...
Physical biology 6 (3), 036001, 2009
1442009
Mechanisms and mechanics of cell competition in epithelia
JP Vincent, AG Fletcher, LAL Baena-Lopez
Nature reviews Molecular cell biology 14 (9), 581-591, 2013
1392013
A PHABULOSA/cytokinin feedback loop controls root growth in Arabidopsis
RD Ioio, C Galinha, AG Fletcher, SP Grigg, A Molnar, V Willemsen, ...
Current Biology 22 (18), 1699-1704, 2012
1382012
Migration and horizontal gene transfer divide microbial genomes into multiple niches
R Niehus, S Mitri, AG Fletcher, KR Foster
Nature communications 6 (1), 8924, 2015
1372015
Unipolar distributions of junctional Myosin II identify cell stripe boundaries that drive cell intercalation throughout Drosophila axis extension
RJ Tetley, GB Blanchard, AG Fletcher, RJ Adams, B Sanson
Elife 5, e12094, 2016
1032016
Mechanocellular models of epithelial morphogenesis
AG Fletcher, F Cooper, RE Baker
Philosophical Transactions of the Royal Society B: Biological Sciences 372 …, 2017
982017
Cell proliferation within small intestinal crypts is the principal driving force for cell migration on villi
A Parker, OJ Maclaren, AG Fletcher, D Muraro, PA Kreuzaler, HM Byrne, ...
The FASEB Journal 31 (2), 636, 2017
922017
Morphological plant modeling: unleashing geometric and topological potential within the plant sciences
A Bucksch, A Atta-Boateng, AF Azihou, D Battogtokh, A Baumgartner, ...
Frontiers in plant science 8, 235043, 2017
782017
Mathematical modeling of monoclonal conversion in the colonic crypt
AG Fletcher, CJW Breward, SJ Chapman
Journal of theoretical biology 300, 118-133, 2012
762012
Elevated apoptosis impairs epithelial cell turnover and shortens villi in TNF-driven intestinal inflammation
A Parker, L Vaux, AM Patterson, A Modasia, D Muraro, AG Fletcher, ...
Cell death & disease 10 (2), 108, 2019
752019
Oxygen consumption dynamics in steady-state tumour models
DR Grimes, AG Fletcher, M Partridge
Royal Society open science 1 (1), 140080, 2014
752014
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