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Mohamad-Gabriel Alameh
Mohamad-Gabriel Alameh
Adresse e-mail validée de pennmedicine.upenn.edu
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D614G spike mutation increases SARS CoV-2 susceptibility to neutralization
D Weissman, MG Alameh, T de Silva, P Collini, H Hornsby, R Brown, ...
Cell Host & Microbe, 2020
3272020
Nanomaterial Delivery Systems for mRNA Vaccines
MGADW Michael D. Buschmann 1, *, Manuel J. Carrasco 1, Suman Alishetty 1 ...
Vaccines 9 (65), 2021
2862021
Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses
MG Alameh, I Tombácz, E Bettini, K Lederer, C Sittplangkoon, JR Wilmore, ...
Immunity, 2021
1532021
siRNA Delivery with Chitosan: Influence of Chitosan Molecular Weight, Degree of Deacetylation, and Amine to Phosphate Ratio on in Vitro Silencing Efficiency, Hemocompatibility …
M Alameh, M Lavertu, N Tran-Khanh, CY Chang, F Lesage, M Bail, ...
Biomacromolecules 19 (1), 112-131, 2017
992017
Low molecular weight chitosan nanoparticulate system at low N: P ratio for nontoxic polynucleotide delivery
M Alameh, D DeJesus, M Jean, V Darras, M Thibault, M Lavertu, ...
International journal of nanomedicine 7, 1399, 2012
952012
An ionizable lipid toolbox for RNA delivery
X Han, H Zhang, K Butowska, KL Swingle, MG Alameh, D Weissman, ...
Nature Communications 12 (1), 1-6, 2021
872021
Chitosan-based therapeutic nanoparticles for combination gene therapy and gene silencing of in vitro cell lines relevant to type 2 diabetes
M Jean, M Alameh, D De Jesus, M Thibault, M Lavertu, V Darras, M Nelea, ...
European Journal of Pharmaceutical Sciences 45 (1), 138-149, 2012
852012
Ionization and structural properties of mRNA lipid nanoparticles influence expression in intramuscular and intravascular administration
MJ Carrasco, S Alishetty, MG Alameh, H Said, L Wright, M Paige, ...
Communications biology 4 (1), 1-15, 2021
822021
Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device
SJ Shepherd, CC Warzecha, S Yadavali, R El-Mayta, MG Alameh, ...
Nano Letters, 2021
782021
Ionizable lipid nanoparticles for in utero mRNA delivery
RS Riley, MV Kashyap, MM Billingsley, B White, MG Alameh, SK Bose, ...
Science Advances 7 (3), eaba1028, 2021
732021
Effective and safe gene-based delivery of GLP-1 using chitosan/plasmid-DNA therapeutic nanocomplexes in an animal model of type 2 diabetes
M Jean, M Alameh, MD Buschmann, A Merzouki
Gene therapy 18 (8), 807, 2011
682011
Messenger RNA-Based Vaccines Against Infectious Diseases
MG Alameh, D Weissman, N Pardi
Springer, Berlin, Heidelberg, 2020
582020
Chitosanase-based method for RNA isolation from cells transfected with chitosan/siRNA nanocomplexes for real-time RT-PCR in gene silencing
M Alameh, M Jean, D DeJesus, MD Buschmann, A Merzouki
International journal of nanomedicine 5, 473, 2010
492010
Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNP
I Tombácz, D Laczkó, H Shahnawaz, H Muramatsu, A Natesan, ...
Molecular Therapy, 2021
452021
Vaccine Technologies and Platforms for Infectious Diseases: Current Progress, Challenges, and Opportunities
M Ghattas, G Dwivedi, M Lavertu, MG Alameh
Vaccines 9 (12), 1490, 2021
362021
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
CP Arevalo, MJ Bolton, V Le Sage, N Ye, C Furey, H Muramatsu, ...
Science 378 (6622), 899-904, 2022
342022
Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models
RL Hajnik, JA Plante, Y Liang, MG Alameh, J Tang, SR Bonam, C Zhong, ...
Science Translational Medicine 14 (662), eabq1945, 2022
232022
Efficiency of Chitosan/Hyaluronan-based mRNA Delivery Systems In Vitro: Influence of Composition and Structure
OY Soliman, MG Alameh, G De Cresenzo, MD Buschmann, M Lavertu
Journal of Pharmaceutical Sciences, 2019
202019
Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery
JR Melamed, KA Hajj, N Chaudhary, D Strelkova, ML Arral, N Pardi, ...
Journal of Controlled Release, 2021
182021
Automated in-line mixing system for large scale production of chitosan-based polyplexes
AT Naeini, OY Soliman, MG Alameh, M Lavertu, MD Buschmann
Journal of Colloid and Interface Science 500, 253-263, 2017
162017
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