|Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways|
GH Werstuck, SR Lentz, S Dayal, GS Hossain, SK Sood, YY Shi, J Zhou, ...
The Journal of clinical investigation 107 (10), 1263-1273, 2001
|Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation|
RK Reddy, C Mao, P Baumeister, RC Austin, RJ Kaufman, AS Lee
Journal of Biological Chemistry 278 (23), 20915-20924, 2003
|Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease|
RC Austin, SR Lentz, GH Werstuck
Cell Death & Differentiation 11 (1), S56-S64, 2004
|Homocysteine-induced endoplasmic reticulum stress and growth arrest leads to specific changes in gene expression in human vascular endothelial cells|
PA Outinen, SK Sood, SI Pfeifer, S Pamidi, TJ Podor, J Li, JI Weitz, ...
Blood, The Journal of the American Society of Hematology 94 (3), 959-967, 1999
|Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E–deficient mice|
J Zhou, S Lhoták, BA Hilditch, RC Austin
Circulation 111 (14), 1814-1821, 2005
|Placental transforming growth factor-β is a downstream mediator of the growth arrest and apoptotic response of tumor cells to DNA damage and p53 overexpression|
PX Li, J Wong, A Ayed, D Ngo, AM Brade, C Arrowsmith, RC Austin, ...
Journal of Biological Chemistry 275 (26), 20127-20135, 2000
|Hyperhomocysteinemia and its role in the development of atherosclerosis|
ABL De Koning, GH Werstuck, J Zhou, RC Austin
Clinical biochemistry 36 (6), 431-441, 2003
|Decreased endogenous production of hydrogen sulfide accelerates atherosclerosis|
S Mani, H Li, A Untereiner, L Wu, G Yang, RC Austin, JG Dickhout, ...
Circulation 127 (25), 2523-2534, 2013
|Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3|
AJ Kim, Y Shi, RC Austin, GH Werstuck
Journal of cell science 118 (1), 89-99, 2005
|Characterization of the stress-inducing effects of homocysteine|
PA OUTINEN, SK SOOD, PCY LIAW, KD SARGE, N MAEDA, J HIRSH, ...
Biochemical journal 332 (1), 213-221, 1998
|TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia|
GS Hossain, JV van Thienen, GH Werstuck, J Zhou, SK Sood, ...
Journal of Biological Chemistry 278 (32), 30317-30327, 2003
|Dietary supplementation with methionine and homocysteine promotes early atherosclerosis but not plaque rupture in ApoE-deficient mice|
J Zhou, J Mųller, CC Danielsen, J Bentzon, HB Ravn, RC Austin, E Falk
Arteriosclerosis, thrombosis, and vascular biology 21 (9), 1470-1476, 2001
|Interrelationship between cardiac hypertrophy, heart failure, and chronic kidney disease: endoplasmic reticulum stress as a mediator of pathogenesis|
JG Dickhout, RE Carlisle, RC Austin
Circulation Research 108 (5), 629-642, 2011
|Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis|
JG Dickhout, GS Hossain, LM Pozza, J Zhou, S Lhoták, RC Austin
Arteriosclerosis, thrombosis, and vascular biology 25 (12), 2623-2629, 2005
|The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response|
S Basseri, Š Lhotįk, AM Sharma, RC Austin
Journal of lipid research 50 (12), 2486-2501, 2009
|Association of multiple cellular stress pathways with accelerated atherosclerosis in hyperhomocysteinemic apolipoprotein E-deficient mice|
J Zhou, GH Werstuck, S Lhoták, ABL de Koning, SK Sood, GS Hossain, ...
Circulation 110 (2), 207-213, 2004
|Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2|
SM Colgan, D Tang, GH Werstuck, RC Austin
The international journal of biochemistry & cell biology 39 (10), 1843-1851, 2007
|Contributions of hyperhomocysteinemia to atherosclerosis: Causal relationship and potential mechanisms|
J Zhou, RC Austin
Biofactors 35 (2), 120-129, 2009
|Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential|
S Basseri, RC Austin
Biochemistry research international 2012, 2012
|Endoplasmic reticulum stress induces hyaluronan deposition and leukocyte adhesion|
AK Majors, RC Austin, A Carol, RE Pyeritz, VC Hascall, SP Kessler, G Sen, ...
Journal of Biological Chemistry 278 (47), 47223-47231, 2003