| Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways GH Werstuck, SR Lentz, S Dayal, GS Hossain, SK Sood, YY Shi, J Zhou, ... The Journal of clinical investigation 107 (10), 1263-1273, 2001 | 907 | 2001 |
| Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation RK Reddy, C Mao, P Baumeister, RC Austin, RJ Kaufman, AS Lee Journal of Biological Chemistry 278 (23), 20915-20924, 2003 | 873 | 2003 |
| Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease RC Austin, SR Lentz, GH Werstuck Cell Death & Differentiation 11 (1), S56-S64, 2004 | 633 | 2004 |
| Homocysteine-induced endoplasmic reticulum stress and growth arrest leads to specific changes in gene expression in human vascular endothelial cells PA Outinen, SK Sood, SI Pfeifer, S Pamidi, TJ Podor, J Li, JI Weitz, ... Blood, The Journal of the American Society of Hematology 94 (3), 959-967, 1999 | 478 | 1999 |
| Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis SL Pinkosky, RS Newton, EA Day, RJ Ford, S Lhotak, RC Austin, ... Nature Communications 7 (1), 13457, 2016 | 423 | 2016 |
| Decreased endogenous production of hydrogen sulfide accelerates atherosclerosis S Mani, H Li, A Untereiner, L Wu, G Yang, RC Austin, JG Dickhout, ... Circulation 127 (25), 2523-2534, 2013 | 421 | 2013 |
| Placental transforming growth factor-β is a downstream mediator of the growth arrest and apoptotic response of tumor cells to DNA damage and p53 overexpression PX Li, J Wong, A Ayed, D Ngo, AM Brade, C Arrowsmith, RC Austin, ... Journal of Biological Chemistry 275 (26), 20127-20135, 2000 | 351 | 2000 |
| Hyperhomocysteinemia and its role in the development of atherosclerosis ABL De Koning, GH Werstuck, J Zhou, RC Austin Clinical biochemistry 36 (6), 431-441, 2003 | 349 | 2003 |
| Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E–deficient mice J Zhou, S Lhoták, BA Hilditch, RC Austin Circulation 111 (14), 1814-1821, 2005 | 348 | 2005 |
| Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3 AJ Kim, Y Shi, RC Austin, GH Werstuck Journal of cell science 118 (1), 89-99, 2005 | 318 | 2005 |
| Characterization of the stress-inducing effects of homocysteine PA OUTINEN, SK SOOD, PCY LIAW, KD SARGE, N MAEDA, J HIRSH, ... Biochemical journal 332 (1), 213-221, 1998 | 294 | 1998 |
| TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia GS Hossain, JV van Thienen, GH Werstuck, J Zhou, SK Sood, ... Journal of Biological Chemistry 278 (32), 30317-30327, 2003 | 278 | 2003 |
| Interrelationship between cardiac hypertrophy, heart failure, and chronic kidney disease: endoplasmic reticulum stress as a mediator of pathogenesis JG Dickhout, RE Carlisle, RC Austin Circulation research 108 (5), 629-642, 2011 | 274 | 2011 |
| Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential S Basseri, RC Austin Biochemistry research international 2012 (1), 841362, 2012 | 263 | 2012 |
| Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis JG Dickhout, GS Hossain, LM Pozza, J Zhou, S Lhoták, RC Austin Arteriosclerosis, thrombosis, and vascular biology 25 (12), 2623-2629, 2005 | 254 | 2005 |
| The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response [S] S Basseri, Š Lhotįk, AM Sharma, RC Austin Journal of lipid research 50 (12), 2486-2501, 2009 | 251 | 2009 |
| Dietary supplementation with methionine and homocysteine promotes early atherosclerosis but not plaque rupture in ApoE-deficient mice J Zhou, J Mųller, CC Danielsen, J Bentzon, HB Ravn, RC Austin, E Falk Arteriosclerosis, thrombosis, and vascular biology 21 (9), 1470-1476, 2001 | 240 | 2001 |
| Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2 SM Colgan, D Tang, GH Werstuck, RC Austin The international journal of biochemistry & cell biology 39 (10), 1843-1851, 2007 | 226 | 2007 |
| Association of multiple cellular stress pathways with accelerated atherosclerosis in hyperhomocysteinemic apolipoprotein E-deficient mice J Zhou, GH Werstuck, S Lhoták, ABL de Koning, SK Sood, GS Hossain, ... Circulation 110 (2), 207-213, 2004 | 219 | 2004 |
| Contributions of hyperhomocysteinemia to atherosclerosis: Causal relationship and potential mechanisms J Zhou, RC Austin Biofactors 35 (2), 120-129, 2009 | 197 | 2009 |
