Gyorgy Hutvagner
Gyorgy Hutvagner
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Asymmetry in the assembly of the RNAi enzyme complex
DS Schwarz, G Hutvágner, T Du, Z Xu, N Aronin, PD Zamore
Cell 115 (2), 199-208, 2003
A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA
G Hutvagner, J McLachlan, AE Pasquinelli, É Bálint, T Tuschl, PD Zamore
Science 293 (5531), 834-838, 2001
A microRNA in a multiple-turnover RNAi enzyme complex
G Hutvagner, PD Zamore
Science 297 (5589), 2056-2060, 2002
Argonaute proteins: key players in RNA silencing
G Hutvagner, MJ Simard
Nature reviews Molecular cell biology 9 (1), 22-32, 2008
Sequence-specific inhibition of small RNA function
G Hutvágner, MJ Simard, CC Mello, PD Zamore
PLoS biology 2 (4), e98, 2004
RNAi: nature abhors a double-strand
G Hutvágner, PD Zamore
Current opinion in genetics & development 12 (2), 225-232, 2002
Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways
DS Schwarz, G Hutvágner, B Haley, PD Zamore
Molecular cell 10 (3), 537-548, 2002
Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs
C Cole, A Sobala, C Lu, SR Thatcher, A Bowman, JWS Brown, PJ Green, ...
Rna 15 (12), 2147-2160, 2009
Principles and effects of microRNA-mediated post-transcriptional gene regulation
BM Engels, G Hutvagner
Oncogene 25 (46), 6163-6169, 2006
Methods and compositions for enhancing the efficacy and specificity of RNA silencing
PD Zamore, G Hutvágner, D Schwarz, M Simard
US Patent 7,750,144, 2010
Small RNAs derived from the 5′ end of tRNA can inhibit protein translation in human cells
A Sobala, G Hutvagner
RNA biology 10 (4), 553-563, 2013
Methods and compositions for enhancing the efficacy and specificity of RNAi
PD Zamore, G Hutvagner, D Schwarz, M Simard
US Patent 8,309,704, 2012
RNA-based therapeutics: from antisense oligonucleotides to miRNAs
S Bajan, G Hutvagner
Cells 9 (1), 137, 2020
Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes
IJ Gallagher, C Scheele, P Keller, AR Nielsen, J Remenyi, CP Fischer, ...
Genome medicine 2, 1-18, 2010
In vivo production of small interfering RNAS that mediate gene silencing
PD Zamore, J McLachlan, G Hutvagner, A Grishok, CC Mello
US Patent 7,691,995, 2010
Small RNA asymmetry in RNAi: function in RISC assembly and gene regulation
G Hutvagner
FEBS letters 579 (26), 5850-5857, 2005
Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins
J Remenyi, CJ Hunter, C Cole, H Ando, S Impey, CE Monk, KJ Martin, ...
Biochemical Journal 428 (2), 281-291, 2010
tRNA-derived fragments (tRFs): emerging new roles for an ancient RNA in the regulation of gene expression
SP Keam, G Hutvagner
Life 5 (4), 1638-1651, 2015
Compositions for RNA interference and methods of use thereof
PD Zamore, G Hutvágner, D Schwarz, G Tang, B Haley
US Patent 8,729,036, 2014
Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells
R Mudhasani, Z Zhu, G Hutvagner, CM Eischen, S Lyle, LL Hall, ...
The Journal of cell biology 181 (7), 1055-1063, 2008
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