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Christophe Schmitt
Christophe Schmitt
Clinical Pharmacology, F. Hoffmann La Roche
Verified email at roche.com
Title
Cited by
Cited by
Year
Emicizumab prophylaxis in hemophilia A with inhibitors
J Oldenburg, JN Mahlangu, B Kim, C Schmitt, MU Callaghan, G Young, ...
New England Journal of Medicine 377 (9), 809-818, 2017
10582017
Emicizumab prophylaxis in patients who have hemophilia A without inhibitors
J Mahlangu, J Oldenburg, I Paz-Priel, C Negrier, M Niggli, ME Mancuso, ...
New England Journal of Medicine 379 (9), 811-822, 2018
6702018
Efficacy, safety, and pharmacokinetics of emicizumab prophylaxis given every 4 weeks in people with haemophilia A (HAVEN 4): a multicentre, open-label, non-randomised phase 3 study
SW Pipe, M Shima, M Lehle, A Shapiro, S Chebon, K Fukutake, NS Key, ...
The Lancet Haematology 6 (6), e295-e305, 2019
3502019
A multicenter, open-label phase 3 study of emicizumab prophylaxis in children with hemophilia A with inhibitors
G Young, RI Liesner, T Chang, R Sidonio Jr, J Oldenburg, ...
Blood, The Journal of the American Society of Hematology 134 (24), 2127-2138, 2019
3262019
The sustained effects of a dual GIP/GLP-1 receptor agonist, NNC0090-2746, in patients with type 2 diabetes
JP Frias, EJ Bastyr, L Vignati, MH Tschoep, C Schmitt, K Owen, ...
Cell Metabolism 26 (2), 343-352. e2, 2017
2782017
Disease–drug–drug interaction involving tocilizumab and simvastatin in patients with rheumatoid arthritis
C Schmitt, B Kuhn, X Zhang, AJ Kivitz, S Grange
Clinical Pharmacology & Therapeutics 89 (5), 735-740, 2011
2612011
Long-term outcomes with emicizumab prophylaxis for hemophilia A with or without FVIII inhibitors from the HAVEN 1-4 studies
MU Callaghan, C Negrier, I Paz-Priel, T Chang, S Chebon, M Lehle, ...
Blood, The Journal of the American Society of Hematology 137 (16), 2231-2242, 2021
2032021
Effects and interferences of emicizumab, a humanised bispecific antibody mimicking activated factor VIII cofactor function, on coagulation assays
JI Adamkewicz, DC Chen, I Paz-Priel
Thrombosis and haemostasis 119 (07), 1084-1093, 2019
1202019
A pharmacometric approach to substitute for a conventional dose-finding study in rare diseases: example of phase III dose selection for emicizumab in hemophilia A
K Yoneyama, C Schmitt, N Kotani, GG Levy, R Kasai, S Iida, M Shima, ...
Clinical Pharmacokinetics 57, 1123-1134, 2018
982018
Laboratory monitoring in emicizumab-treated persons with hemophilia A
J Müller, I Pekrul, B Pötzsch, B Berning, J Oldenburg, M Spannagl
Thrombosis and Haemostasis 119 (09), 1384-1393, 2019
832019
Pharmacokinetics and pharmacodynamics of emicizumab in persons with hemophilia A with factor VIII inhibitors: HAVEN 1 study
C Schmitt, JI Adamkewicz, J Xu, C Petry, O Catalani, G Young, C Negrier, ...
Thrombosis and Haemostasis 121 (03), 351-360, 2021
762021
HAVEN 2 updated analysis: multicenter, open-label, phase 3 study to evaluate efficacy, safety and pharmacokinetics of subcutaneous administration of emicizumab prophylaxis in …
G Young, RF Sidonio, R Liesner, J Oldenburg, T Chang, M Uguen, ...
Blood 130, 85, 2017
692017
Pharmacodynamics, pharmacokinetics and safety of multiple ascending doses of the novel dual glucose‐dependent insulinotropic polypeptide/glucagon‐like peptide‐1 agonist RG 7697 …
C Schmitt, A Portron, S Jadidi, N Sarkar, R DiMarchi
Diabetes, Obesity and Metabolism 19 (10), 1436-1445, 2017
672017
Immunogenicity of emicizumab in people with hemophilia A (PwHA): results from the HAVEN 1-4 studies
I Paz-Priel, T Chang, E Asikanius, S Chebon, T Emrich, E Fernandez, ...
Blood 132, 633, 2018
662018
Emicizumab prophylaxis provides flexible and effective bleed control in children with hemophilia Α with inhibitors: results from the HAVEN 2 study
G Young, R Liesner, RF Sidonio Jr, J Oldenburg, V Jimenez-Yuste, ...
Blood 132, 632, 2018
632018
Unexpected hepatotoxicity of rifampin and saquinavir/ritonavir in healthy male volunteers
C Schmitt, M Riek, K Winters, M Schutz, S Grange
Archives of drug information 2 (1), 8-16, 2009
592009
Pharmacological control of platelet-leukocyte interactions by the human anti-P-selectin antibody inclacumab–preclinical and clinical studies
D Kling, C Stucki, S Kronenberg, D Tuerck, E Rhéaume, JC Tardif, ...
Thrombosis Research 131 (5), 401-410, 2013
542013
First-in-man study with inclacumab, a human monoclonal antibody against P-selectin
C Schmitt, M Abt, C Ciorciaro, D Kling, C Jamois, E Schick, C Solier, ...
Journal of cardiovascular pharmacology 65 (6), 611-619, 2015
482015
Pharmacodynamics, pharmacokinetics, safety and tolerability of the novel dual glucose‐dependent insulinotropic polypeptide/glucagon‐like peptide‐1 agonist RG 7697 after single …
A Portron, S Jadidi, N Sarkar, R DiMarchi, C Schmitt
Diabetes, Obesity and Metabolism 19 (10), 1446-1453, 2017
422017
Disease-drug interaction studies of tocilizumab with cytochrome P450 substrates in vitro and in vivo
X Zhang, C Schmitt, S Grange, K Terao, K Miya, A Kivitz, M Marino
Clinical Pharmacology & Therapeutics 85, S59-S59, 2009
402009
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