| Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity K Vriens, S Christen, S Parik, D Broekaert, K Yoshinaga, A Talebi, ... Nature 566 (7744), 403-406, 2019 | 366 | 2019 |
| HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients W Guo, M Naujock, L Fumagalli, T Vandoorne, P Baatsen, R Boon, ... Nature communications 8 (1), 861, 2017 | 342 | 2017 |
| Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells I Elia, D Broekaert, S Christen, R Boon, E Radaelli, MF Orth, C Verfaillie, ... Nature communications 8 (1), 15267, 2017 | 337 | 2017 |
| Breast cancer cells rely on environmental pyruvate to shape the metastatic niche I Elia, M Rossi, S Stegen, D Broekaert, G Doglioni, M van Gorsel, R Boon, ... Nature 568 (7750), 117-121, 2019 | 248 | 2019 |
| Generation of hepatic stellate cells from human pluripotent stem cells enables in vitro modeling of liver fibrosis M Coll, L Perea, R Boon, SB Leite, J Vallverdú, I Mannaerts, A Smout, ... Cell stem cell 23 (1), 101-113. e7, 2018 | 201 | 2018 |
| Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis C Lange, M Turrero Garcia, I Decimo, F Bifari, G Eelen, A Quaegebeur, ... The EMBO journal 35 (9), 924-941, 2016 | 198 | 2016 |
| Efficient recombinase-mediated cassette exchange in hPSCs to study the hepatocyte lineage reveals AAVS1 locus-mediated transgene inhibition L Ordovás, R Boon, M Pistoni, Y Chen, E Wolfs, W Guo, R Sambathkumar, ... Stem cell reports 5 (5), 918-931, 2015 | 135 | 2015 |
| SOX10 single transcription factor-based fast and efficient generation of oligodendrocytes from human pluripotent stem cells JA García-León, M Kumar, R Boon, D Chau, J One, E Wolfs, K Eggermont, ... Stem cell reports 10 (2), 655-672, 2018 | 103 | 2018 |
| Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines R Boon, M Kumar, T Tricot, I Elia, L Ordovas, F Jacobs, J One, J De Smedt, ... Nature communications 11 (1), 1393, 2020 | 101 | 2020 |
| Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways JK Manesia, Z Xu, D Broekaert, R Boon, A van Vliet, G Eelen, ... Stem cell research 15 (3), 715-721, 2015 | 83 | 2015 |
| Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors D Lorendeau, G Rinaldi, R Boon, P Spincemaille, K Metzger, C Jäger, ... Metabolic engineering 43, 187-197, 2017 | 78 | 2017 |
| Nuclear metabolism and the regulation of the epigenome R Boon, GG Silveira, R Mostoslavsky Nature Metabolism 2 (11), 1190-1203, 2020 | 71 | 2020 |
| Human stem cell–derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2 C Claes, J Van Den Daele, R Boon, S Schouteden, A Colombo, ... Alzheimer's & Dementia 15 (3), 453-464, 2019 | 71 | 2019 |
| HDAC6 inhibition restores TDP‐43 pathology and axonal transport defects in human motor neurons with TARDBP mutations R Fazal, S Boeynaems, A Swijsen, M De Decker, L Fumagalli, M Moisse, ... The EMBO journal 40 (7), e106177, 2021 | 64 | 2021 |
| Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication N Helsen, Y Debing, J Paeshuyse, K Dallmeier, R Boon, M Coll, ... Journal of Hepatology 64 (3), 565-573, 2016 | 59 | 2016 |
| PU. 1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells J De Smedt, EA van Os, I Talon, S Ghosh, B Toprakhisar, ... Cell death & disease 12 (1), 84, 2021 | 25 | 2021 |
| A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma JE Choi, C Sebastian, CM Ferrer, CA Lewis, M Sade-Feldman, T LaSalle, ... Nature metabolism 3 (2), 182-195, 2021 | 23 | 2021 |
| H3K27me3 does not orchestrate the expression of lineage-specific markers in hESC-derived hepatocytes in vitro J Vanhove, M Pistoni, M Welters, K Eggermont, V Vanslembrouck, ... Stem Cell Reports 7 (2), 192-206, 2016 | 22 | 2016 |
| A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model M Kumar, B Toprakhisar, M Van Haele, A Antoranz, R Boon, F Chesnais, ... Biomaterials 276, 121006, 2021 | 21 | 2021 |
| Metabolic fuel for epigenetic: nuclear production meets local consumption R Boon Frontiers in Genetics 12, 768996, 2021 | 19 | 2021 |
Catherine VerfaillieKU LeuvenVerified email at med.kuleuven.be
