C16-ceramide is a natural regulatory ligand of p53 in cellular stress response B Fekry, KA Jeffries, A Esmaeilniakooshkghazi, ZM Szulc, KJ Knagge, ... Nature communications 9 (1), 4149, 2018 | 89 | 2018 |
Villin-1 and gelsolin regulate changes in actin dynamics that affect cell survival signaling pathways and intestinal inflammation S Roy, A Esmaeilniakooshkghazi, S Patnaik, Y Wang, SP George, ... Gastroenterology 154 (5), 1405-1420. e2, 2018 | 56 | 2018 |
Ceramide synthase 6 is a novel target of methotrexate mediating its antiproliferative effect in a p53-dependent manner B Fekry, A Esmaeilniakooshkghazi, SA Krupenko, NI Krupenko PLoS One 11 (1), e0146618, 2016 | 49 | 2016 |
CerS6 is a novel transcriptional target of p53 protein activated by non-genotoxic stress B Fekry, KA Jeffries, A Esmaeilniakooshkghazi, B Ogretmen, ... Journal of Biological Chemistry 291 (32), 16586-16596, 2016 | 47 | 2016 |
Advillin acts upstream of phospholipase C ϵ1 in steroid-resistant nephrotic syndrome J Rao, S Ashraf, W Tan, AT Van Der Ven, HY Gee, DA Braun, K Fehér, ... The Journal of Clinical Investigation 127 (12), 4257-4269, 2017 | 45 | 2017 |
Both the anti-and pro-apoptotic functions of villin regulate cell turnover and intestinal homeostasis Y Wang, SP George, S Roy, E Pham, A Esmaeilniakooshkghazi, ... Scientific reports 6 (1), 35491, 2016 | 27 | 2016 |
CHIP E3 ligase mediates proteasomal degradation of the proliferation regulatory protein ALDH1L1 during the transition of NIH3T3 fibroblasts from G0/G1 to S-phase QA Khan, P Pediaditakis, Y Malakhau, A Esmaeilniakooshkghazi, ... PLoS One 13 (7), e0199699, 2018 | 19 | 2018 |
Mouse intestinal tuft cells express advillin but not villin A Esmaeilniakooshkghazi, SP George, R Biswas, S Khurana Scientific Reports 10 (1), 8877, 2020 | 17 | 2020 |
F–actin-bundling sites are conserved in proteins with villin-type headpiece domains SP George, A Esmaeilniakooshkghazi, S Roy, S Khurana Molecular Biology of the Cell 31 (17), 1857-1866, 2020 | 4 | 2020 |
In colon cancer cells fascin1 regulates adherens junction remodeling A Esmaeilniakooshkghazi, E Pham, SP George, A Ahrorov, ... The FASEB Journal 37 (3), e22786, 2023 | 3 | 2023 |
Fascin1 accelerates serrated pathway carcinogenesis by remodeling adherens junctions and restoring Wnt signaling A Esmaeilniakooshkghazi, E Pham, SP George, A Ahrorov, ... bioRxiv, 2022.06. 14.496198, 2022 | | 2022 |
Actin Dynamics Arrest by Loss of Villin and Gelsolin Perturb Intestinal Epithelium Mitochondria Homeostasis--Link to Crohn's Disease Y Wang, S Roy, G Sudeep, S Patnaik, A Esmaeilniakooshkghazi, ... LABORATORY INVESTIGATION 98, 308-309, 2018 | | 2018 |
A New Paradigm in Intestinal Epithelial Self-Defense: Changes in Actin Dynamics Regulated by Villin and Gelsolin are Determinants of Host Defense S Roy, S Patnaik, Y Wang, A Esmaeilniakooshkghazi, SP George, JK Hou, ... Gastroenterology 152 (5), S969, 2017 | | 2017 |
F-actin bundling sites are conserved in proteins with villin type headpiece domains. S Khurana, S George, A Esmaeilniakooshkghazi, S Roy | | |
In BRAFV600E-mutated colorectal cancer cells, fascin1 restructures adherens junctions to drive Wnt activation. E Pham, A Esmaeilniakooshkghazi, SP George, A Ahrorov, ... | | |