| Dacomitinib antagonizes multidrug resistance (MDR) in cancer cells by inhibiting the efflux activity of ABCB1 and ABCG2 transporters YF Fan, W Zhang, L Zeng, ZN Lei, CY Cai, P Gupta, DH Yang, Q Cui, ... Cancer letters 421, 186-198, 2018 | 108 | 2018 |
| Selonsertib (GS-4997), an ASK1 inhibitor, antagonizes multidrug resistance in ABCB1-and ABCG2-overexpressing cancer cells N Ji, Y Yang, CY Cai, ZN Lei, JQ Wang, P Gupta, S Shukla, SV Ambudkar, ... Cancer letters 440, 82-93, 2019 | 99 | 2019 |
| Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID-19 ZN Lei, ZX Wu, S Dong, DH Yang, L Zhang, Z Ke, C Zou, ZS Chen Pharmacology & Therapeutics 216, 107672, 2020 | 80 | 2020 |
| ATP‐binding cassette (ABC) transporters in cancer: A review of recent updates JQ Wang, ZX Wu, Y Yang, QX Teng, YD Li, ZN Lei, KA Jani, N Kaushal, ... Journal of Evidence‐Based Medicine 14 (3), 232-256, 2021 | 73 | 2021 |
| Signaling pathways and therapeutic interventions in gastric cancer ZN Lei, QX Teng, Q Tian, W Chen, Y Xie, K Wu, Q Zeng, L Zeng, Y Pan, ... Signal Transduction and Targeted Therapy 7 (1), 358, 2022 | 72 | 2022 |
| Discovery of 5-cyano-6-phenylpyrimidin derivatives containing an acylurea moiety as orally bioavailable reversal agents against P-glycoprotein-mediated mutidrug resistance B Wang, LY Ma, JQ Wang, ZN Lei, P Gupta, YD Zhao, ZH Li, Y Liu, ... Journal of medicinal chemistry 61 (14), 5988-6001, 2018 | 63 | 2018 |
| Tepotinib reverses ABCB1-mediated multidrug resistance in cancer cells ZX Wu, QX Teng, CY Cai, JQ Wang, ZN Lei, Y Yang, YF Fan, JY Zhang, ... Biochemical pharmacology 166, 120-127, 2019 | 57 | 2019 |
| Olmutinib (BI1482694/HM61713), a novel epidermal growth factor receptor tyrosine kinase inhibitor, reverses ABCG2-mediated multidrug resistance in cancer cells W Zhang, YF Fan, CY Cai, JQ Wang, QX Teng, ZN Lei, L Zeng, P Gupta, ... Frontiers in pharmacology 9, 1097, 2018 | 56 | 2018 |
| Tetrandrine Interaction with ABCB1 Reverses Multidrug Resistance in Cancer Cells Through Competition with Anti-Cancer Drugs Followed by Downregulation of ABCB1 Expression D Liao, W Zhang, P Gupta, ZN Lei, JQ Wang, CY Cai, AAD Vera, L Zhang, ... Molecules 24 (23), 4383, 2019 | 54 | 2019 |
| VS-4718 antagonizes multidrug resistance in ABCB1-and ABCG2-overexpressing cancer cells by inhibiting the efflux function of ABC transporters N Ji, Y Yang, CY Cai, ZN Lei, JQ Wang, P Gupta, QX Teng, ZS Chen, ... Frontiers in Pharmacology 9, 1236, 2018 | 52 | 2018 |
| Immuno-oncology agent IPI-549 is a modulator of P-glycoprotein (P-gp, MDR1, ABCB1)-mediated multidrug resistance (MDR) in cancer: In vitro and in vivo AA De Vera, P Gupta, Z Lei, D Liao, S Narayanan, Q Teng, SE Reznik, ... Cancer letters 442, 91-103, 2019 | 50 | 2019 |
| Ulixertinib (BVD-523) antagonizes ABCB1-and ABCG2-mediated chemotherapeutic drug resistance N Ji, Y Yang, ZN Lei, CY Cai, JQ Wang, P Gupta, X Xian, DH Yang, ... Biochemical pharmacology 158, 274-285, 2018 | 49 | 2018 |
| Venetoclax, a BCL-2 Inhibitor, Enhances the Efficacy of Chemotherapeutic Agents in Wild-Type ABCG2-Overexpression-Mediated MDR Cancer Cells JQ Wang, JY Li, QX Teng, ZN Lei, N Ji, Q Cui, L Zeng, Y Pan, DH Yang, ... Cancers 12 (2), 466, 2020 | 44 | 2020 |
| Tivantinib, A c-Met Inhibitor in Clinical Trials, Is Susceptible to ABCG2-Mediated Drug Resistance ZX Wu, Y Yang, QX Teng, JQ Wang, ZN Lei, JQ Wang, S Lusvarghi, ... Cancers 12 (1), 186, 2020 | 39 | 2020 |
| PP2A–AMPKα–HSF1 axis regulates the metal-inducible expression of HSPs and ROS clearance X Zhu, L Chen, Q Bai, L Ma, D Li, J Zhang, C Gao, Z Lei, Z Zhang, X Xing, ... Cellular signalling 26 (4), 825-832, 2014 | 38 | 2014 |
| Overexpression of ABCB1 Transporter Confers Resistance to mTOR Inhibitor WYE-354 in Cancer Cells J Wang, DH Yang, Y Yang, JQ Wang, CY Cai, ZN Lei, QX Teng, ZX Wu, ... International journal of molecular sciences 21 (4), 1387, 2020 | 35 | 2020 |
| Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against inflammatory arthritis R Liu, Y Chen, W Fu, S Wang, Y Cui, X Zhao, ZN Lei, A Hettinghouse, ... Annals of the rheumatic diseases 78 (11), 1524-1535, 2019 | 35 | 2019 |
| Regorafenib antagonizes BCRP-mediated multidrug resistance in colon cancer YK Zhang, YJ Wang, ZN Lei, GN Zhang, XY Zhang, D Wang, SB Al-Rihani, ... Cancer letters 442, 104-112, 2019 | 35 | 2019 |
| Sitravatinib, a Tyrosine Kinase Inhibitor, Inhibits the Transport Function of ABCG2 and Restores Sensitivity to Chemotherapy-Resistant Cancer Cells in vitro Y Yang, N Ji, QX Teng, CY Cai, JQ Wang, ZX Wu, ZN Lei, S Lusvarghi, ... Frontiers in Oncology 10, 700, 2020 | 34 | 2020 |
| Genetic biomarkers of drug resistance: A compass of prognosis and targeted therapy in acute myeloid leukemia L Long, YG Assaraf, ZN Lei, H Peng, L Yang, ZS Chen, S Ren Drug Resistance Updates 52, 100703, 2020 | 32 | 2020 |
