| Human intestinal maltase–glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity L Sim, R Quezada-Calvillo, EE Sterchi, BL Nichols, DR Rose Journal of Molecular Biology 375 (3), 782-792, 2008 | 332 | 2008 |
| Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains L Sim, C Willemsma, S Mohan, HY Naim, BM Pinto, DR Rose Journal of Biological Chemistry 285 (23), 17763-17770, 2010 | 236 | 2010 |
| New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from … L Sim, K Jayakanthan, S Mohan, R Nasi, BD Johnston, BM Pinto, ... Biochemistry 49 (3), 443-451, 2010 | 202 | 2010 |
| Luminal Starch Substrate “Brake” on Maltase-Glucoamylase Activity Is Located within the Glucoamylase Subunit3 R Quezada-Calvillo, L Sim, Z Ao, BR Hamaker, A Quaroni, GD Brayer, ... The Journal of nutrition 138 (4), 685-692, 2008 | 118 | 2008 |
| Total Syntheses of Casuarine and Its 6‐O‐α‐Glucoside: Complementary Inhibition towards Glycoside Hydrolases of the GH31 and GH37 Families F Cardona, C Parmeggiani, E Faggi, C Bonaccini, P Gratteri, L Sim, ... Chemistry–A European Journal 15 (7), 1627-1636, 2009 | 112 | 2009 |
| Inhibition of recombinant human maltase glucoamylase by salacinol and derivatives EJ Rossi, L Sim, DA Kuntz, D Hahn, BD Johnston, A Ghavami, ... The FEBS journal 273 (12), 2673-2683, 2006 | 111 | 2006 |
| Mapping the intestinal alpha-glucogenic enzyme specificities of starch digesting maltase-glucoamylase and sucrase-isomaltase K Jones, L Sim, S Mohan, J Kumarasamy, H Liu, S Avery, HY Naim, ... Bioorganic & medicinal chemistry 19 (13), 3929-3934, 2011 | 100 | 2011 |
| Evidence of native starch degradation with human small intestinal maltase-glucoamylase (recombinant) Z Ao, R Quezada-Calvillo, L Sim, BL Nichols, DR Rose, EE Sterchi, ... FEBS letters 581 (13), 2381-2388, 2007 | 85 | 2007 |
| An enzymatic pathway in the human gut microbiome that converts A to universal O type blood P Rahfeld, L Sim, H Moon, I Constantinescu, C Morgan-Lang, SJ Hallam, ... Nature Microbiology 4 (9), 1475-1485, 2019 | 80 | 2019 |
| Unexpected high digestion rate of cooked starch by the Ct-maltase-glucoamylase small intestine mucosal α-glucosidase subunit AHM Lin, BL Nichols, R Quezada-Calvillo, SE Avery, L Sim, DR Rose, ... PLoS One 7 (5), e35473, 2012 | 63 | 2012 |
| Crystal structure of the Chlamydomonas starch debranching enzyme isoamylase ISA1 reveals insights into the mechanism of branch trimming and complex assembly L Sim, SR Beeren, J Findinier, D Dauvillée, SG Ball, A Henriksen, ... Journal of Biological Chemistry 289 (33), 22991-23003, 2014 | 58 | 2014 |
| New synthetic routes to chain-extended selenium, sulfur, and nitrogen analogues of the naturally occurring glucosidase inhibitor salacinol and their inhibitory activities … H Liu, R Nasi, K Jayakanthan, L Sim, H Heipel, DR Rose, BM Pinto The Journal of organic chemistry 72 (17), 6562-6572, 2007 | 51 | 2007 |
| Studies directed toward the stereochemical structure determination of the naturally occurring glucosidase inhibitor, kotalanol: Synthesis and inhibitory activities against … R Nasi, BO Patrick, L Sim, DR Rose, BM Pinto The Journal of Organic Chemistry 73 (16), 6172-6181, 2008 | 49 | 2008 |
| A new class of glucosidase inhibitor: Analogues of the naturally occurring glucosidase inhibitor salacinol with different ring heteroatom substituents and acyclic chain extension H Liu, L Sim, DR Rose, BM Pinto The Journal of Organic Chemistry 71 (8), 3007-3013, 2006 | 49 | 2006 |
| New chain-extended analogues of salacinol and blintol and their glycosidase inhibitory activities. Mapping the active-site requirements of human maltase glucoamylase R Nasi, L Sim, DR Rose, BM Pinto The Journal of organic chemistry 72 (1), 180-186, 2007 | 48 | 2007 |
| A bacterial expression platform for production of therapeutic proteins containing human-like O-linked glycans T Du, N Buenbrazo, L Kell, S Rahmani, L Sim, SG Withers, S DeFrees, ... Cell chemical biology 26 (2), 203-212. e5, 2019 | 46 | 2019 |
| Oligosaccharide and substrate binding in the starch debranching enzyme barley limit dextrinase MS Møller, MS Windahl, L Sim, M Bøjstrup, M Abou Hachem, O Hindsgaul, ... Journal of molecular biology 427 (6), 1263-1277, 2015 | 39 | 2015 |
| Convergent evolution of polysaccharide debranching defines a common mechanism for starch accumulation in cyanobacteria and plants U Cenci, M Chabi, M Ducatez, C Tirtiaux, J Nirmal-Raj, Y Utsumi, ... The Plant cell 25 (10), 3961-3975, 2013 | 31 | 2013 |
| Synthesis of S-alkylated sulfonium-ions and their glucosidase inhibitory activities against recombinant human maltase glucoamylase S Mohan, L Sim, DR Rose, BM Pinto Carbohydrate research 342 (7), 901-912, 2007 | 28 | 2007 |
| Structural and biochemical characterization of the N‐terminal domain of flocculin Lg‐Flo1p from Saccharomyces pastorianus reveals a unique specificity for … L Sim, M Groes, K Olesen, A Henriksen The FEBS journal 280 (4), 1073-1083, 2013 | 21 | 2013 |
