| Optimization of ligands using focused DNA-encoded libraries to develop a selective, cell-permeable CBX8 chromodomain inhibitor S Wang, KE Denton, KF Hobbs, T Weaver, JMB McFarlane, KE Connelly, ... ACS chemical biology 15 (1), 112-131, 2019 | 58 | 2019 |
| Compositional and functional diversity of canonical PRC1 complexes in mammals KE Connelly, EC Dykhuizen Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1860 (2), 233-245, 2017 | 57 | 2017 |
| Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association KE Connelly, TM Weaver, A Alpsoy, BX Gu, CA Musselman, ... Nucleic acids research 47 (5), 2289-2305, 2019 | 44 | 2019 |
| Analysis of human nuclear protein complexes by quantitative mass spectrometry profiling KE Connelly, V Hedrick, TJ Paschoal Sobreira, EC Dykhuizen, UK Aryal Proteomics 18 (11), 1700427, 2018 | 30 | 2018 |
| The EZH2 SANT1 domain is a histone reader providing sensitivity to the modification state of the H4 tail TM Weaver, J Liu, KE Connelly, C Coble, K Varzavand, EC Dykhuizen, ... Scientific Reports 9 (1), 987, 2019 | 22 | 2019 |
| Sequential Salt Extractions for the Analysis of Bulk Chromatin Binding Properties of Chromatin Modifying Complexes. EG Porter, KE Connelly, C Dykhuizen, Emily Journal of Visualized Experiments, 2017 | 22 | 2017 |
| A 584 bp deletion in CTRB2 inhibits chymotrypsin B2 activity and secretion and confers risk of pancreatic cancer A Jermusyk, J Zhong, KE Connelly, N Gordon, S Perera, E Abdolalizadeh, ... The American Journal of Human Genetics 108 (10), 1852-1865, 2021 | 19 | 2021 |
| Focus: Epigenetics: CBX Chromodomain Inhibition Enhances Chemotherapy Response in Glioblastoma Multiforme KE Connelly, EC Martin, EC Dykhuizen The Yale Journal of Biology and Medicine 89 (4), 431, 2016 | 8 | 2016 |
| Polycomb paralog chromodomain inhibitors active against both CBX6 and CBX8 N Milosevich, CR Wilson, TM Brown, A Alpsoy, S Wang, KE Connelly, ... ChemMedChem 16 (19), 3027-3034, 2021 | 7 | 2021 |
| Inferred expression regulator activities suggest genes mediating cardiometabolic genetic signals JW Hoskins, CC Chung, A O’Brien, J Zhong, K Connelly, I Collins, J Shi, ... PLOS Computational Biology 17 (11), e1009563, 2021 | 2 | 2021 |
| Uncovering the functional variants and target genes of the 7q32 pancreatic cancer risk locus A O'Brien, JW Hoskins, DR Eiser, KE Connelly, J Zhong, T Andresson, ... Cancer Research 82 (12_Supplement), 1475-1475, 2022 | | 2022 |
| Abstract IA-11: An exception to the rule: A coding functional variant at a pancreatic cancer GWAS locus A Jermusyk, J Zhong, N Gordon, K Connelly, S Perera, E Abdolalizadeh, ... Cancer Research 80 (22_Supplement), IA-11-IA-11, 2020 | | 2020 |
| Analysis of Human Nuclear Protein Complexes by Quantitative Mass Spectrometry Profiling U Aryal, KE Connelly, V Hedrick, TJP Sobreira, EC Dykhuizen Journal of Biomolecular Techniques: JBT 30 (Suppl), S5, 2019 | | 2019 |
| The EZH2 SANT1 Domain is a Histone Reader Providing Sensitivity to the Modification State of the H4 Tail TM Weaver, J Liu, KE Connelly, C Coble, K Varzavand, EC Dykhuizen, ... Biophysical Journal 114 (3), 445a, 2018 | | 2018 |
| Understanding the Contributions of the Polycomb CBX Paralogs in Binding and Oncogensis KE Connelly Purdue University, 2018 | | 2018 |
