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Carlos Moreno-Yruela
Carlos Moreno-Yruela
EPFL, Institute of Chemical Sciences and Engineering
Verified email at epfl.ch
Title
Cited by
Cited by
Year
Class I Histone Deacetylases (HDAC1‒3) are Histone Lysine Delactylases
C Moreno-Yruela, D Zhang, W Wei, M Baek, W Liu, J Gao, D Danková, ...
Science Advances 8 (3), eabi6696, 2022
1622022
Histone deacetylase 11 is an ε-N-myristoyllysine hydrolase
C Moreno-Yruela, I Galleano, AS Madsen, CA Olsen
Cell Chemical Biology 25 (7), 849-856, 2018
1222018
D− π–A compounds with tunable intramolecular charge transfer achieved by incorporation of butenolide nitriles as acceptor moieties
C Moreno-Yruela, J Garín, J Orduna, S Franco, E Quintero, ...
The Journal of Organic Chemistry 80 (24), 12115-12128, 2015
532015
Mechanism-based inhibitors of SIRT2: structure–activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer …
AL Nielsen, N Rajabi, N Kudo, K Lundø, C Moreno-Yruela, M Bæk, ...
RSC Chemical Biology 2 (2), 612-626, 2021
322021
Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases
C Moreno-Yruela, M Bæk, AE Vrsanova, C Schulte, HM Maric, CA Olsen
Nature Communications 12 (1), 62, 2021
262021
Chiral Posttranslational Modification to Lysine epsilon-Amino Groups
C Moreno–Yruela, M Bæk, F Monda, CA Olsen
Accounts of Chemical Research 55 (10), 1456–1466, 2022
212022
Zn2+-Dependent Histone Deacetylases in Plants: Structure and Evolution
I Yruela, C Moreno-Yruela, CA Olsen
Trends in Plant Science 26 (7), 741-757, 2021
202021
Kinetic tuning of HDAC inhibitors affords potent inducers of progranulin expression
C Moreno-Yruela, DM Fass, C Cheng, J Herz, CA Olsen, SJ Haggarty
ACS Chemical Neuroscience 10 (8), 3769-3777, 2019
202019
Synthesis of trifluoromethyl ketone containing amino acid building blocks for the preparation of peptide-based histone deacetylase (HDAC) inhibitors
C Moreno-Yruela, CA Olsen
Synthesis 50 (20), 4037-4046, 2018
132018
Determination of Slow-binding HDAC Inhibitor Potency and Subclass Selectivity
C Moreno-Yruela, CA Olsen
ACS Medicinal Chemistry Letters 13 (5), 779–785, 2022
122022
High-throughput screening of histone deacetylases and determination of kinetic parameters using fluorogenic assays
C Moreno-Yruela, CA Olsen
STAR Protocols 2 (1), 100313, 2021
62021
V-shaped pyranylidene/triphenylamine-based chromophores with enhanced photophysical, electrochemical and nonlinear optical properties
S Gámez-Valenzuela, D Neusser, C Benitez-Martin, F Najera, JA Guadix, ...
Materials Advances 2 (13), 4255-4263, 2021
62021
Kinetic characterization of inhibitors of histone deacetylases (HDACs) and sirtuins
C Moreno-Yruela, AS Madsen, CA Olsen
Protocol Exchange, 2019
62019
Revealing chromatin-specific functions of histone deacylases
C Moreno-Yruela, B Fierz
Biochemical Society Transactions 52 (1), 353–365, 2024
2024
Hydroxamic acid-containing peptides in the study of histone deacetylases
C Moreno-Yruela, CA Olsen
Chemical Epigenetics, 20-54, 2020
2020
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