Philip E.D. Chung
Philip E.D. Chung
University Health Network, University of Toronto
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RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation
RA Jones, TJ Robinson, JC Liu, M Shrestha, V Voisin, YJ Ju, PED Chung, ...
The Journal of clinical investigation 126 (10), 3739-3757, 2016
RB1 and p53 at the crossroad of EMT and triple-negative breast cancer
Z Jiang, R Jones, JC Liu, T Deng, T Robinson, PED Chung, S Wang, ...
Cell cycle 10 (10), 1563-1570, 2011
Mitochondrial OXPHOS induced by RB1 deficiency in breast cancer: implications for anabolic metabolism, stemness, and metastasis
E Zacksenhaus, M Shrestha, JC Liu, I Vorobieva, PED Chung, YJ Ju, ...
Trends in cancer 3 (11), 768-779, 2017
Recent acquisition of imprinting at the rodent Sfmbt2 locus correlates with insertion of a large block of miRNAs
Q Wang, J Chow, J Hong, AF Smith, C Moreno, P Seaby, P Vrana, K Miri, ...
BMC genomics 12, 1-11, 2011
Cdh1 and Pik3ca mutations cooperate to induce immune-related invasive lobular carcinoma of the breast
Y An, JR Adams, DP Hollern, A Zhao, SG Chang, MS Gams, PED Chung, ...
Cell reports 25 (3), 702-714. e6, 2018
shRNA Kinome Screen Identifies TBK1 as a Therapeutic Target for HER2+ Breast Cancer
T Deng, JC Liu, PED Chung, D Uehling, A Aman, B Joseph, T Ketela, ...
Cancer research 74 (7), 2119-2130, 2014
Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy
PED Chung, DMA Gendoo, R Ghanbari-Azarnier, JC Liu, Z Jiang, J Tsui, ...
Nature communications 11 (1), 1825, 2020
Targeting HER2+ breast cancer: the TBK1/IKKε axis
Z Jiang, JC Liu, PED Chung, SE Egan, E Zacksenhaus
Oncoscience 1 (2), 180, 2014
Novel racemosin B derivatives as new therapeutic agents for aggressive breast cancer
X Xiao, M Xu, C Yang, Y Yao, L Liang, PED Chung, Q Long, ...
Bioorganic & Medicinal Chemistry 26 (23-24), 6096-6104, 2018
CDC25 as a common therapeutic target for triple-negative breast cancer-the challenges ahead
E Zacksenhaus, JC Liu, L Granieri, I Vorobieva, DY Wang, ...
Molecular & cellular oncology 5 (4), e1481814, 2018
Hypophosphorylated pRb knock‐in mice exhibit hallmarks of aging and vitamin C‐preventable diabetes
Z Jiang, H Li, SA Schroer, V Voisin, YJ Ju, M Pacal, N Erdmann, W Shi, ...
The EMBO Journal 41 (4), e106825, 2022
Virally encoded connectivity transgenic overlay RNA sequencing (VECTORseq) defines projection neurons involved in sensorimotor integration
V Cheung, P Chung, M Bjorni, VA Shvareva, YC Lopez, EH Feinberg
Cell reports 37 (12), 2021
KNP-301, a dual inhibitor of the complement pathway and angiogenesis, effectively suppresses angiogenesis and atrophy
EDP Chung, D Kim, S Ryu, J Chang, BC Lee
Investigative Ophthalmology & Visual Science 62 (8), 183-183, 2021
Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer
Z Jiang, YJ Ju, A Ali, PED Chung, P Skowron, DY Wang, M Shrestha, H Li, ...
Nature communications 14 (1), 4313, 2023
A temporal in vivo catalog of chromatin accessibility and expression profiles in pineoblastoma reveals a prevalent role for repressor elements
S Idriss, M Hallal, A El-Kurdi, H Zalzali, I El-Rassi, EA Ehli, CM Davis, ...
Genome Research 33 (2), 269-282, 2023
A racemosin B derivative, C25, suppresses breast cancer growth via lysosomal membrane permeabilization and inhibition of autophagic flux
X Xiao, PED Chung, M Xu, A Hu, Y Ju, X Yang, J Song, J Song, C Wang, ...
Biochemical Pharmacology 201, 115060, 2022
Thinking (Metastasis) outside the (Primary Tumor) Box
Z Jiang, YJ Ju, A Ali, PED Chung, DY Wang, JC Liu, H Li, I Vorobieva, ...
Cancers 15 (22), 5315, 2023
Transcriptional profiling of mouse projection neurons with VECTORseq
V Cheung, P Chung, EH Feinberg
STAR protocols 3 (3), 101625, 2022
Methylation data of mouse Rb-deficient pineoblastoma
PED Chung, E Zacksenhaus
Data in Brief 32, 106229, 2020
CDC25 as a common therapeutic target for triple-negative breast cancer-the challenges ahead
RGA Wang, H Li, A Ali, PED Chung, YJ Ju, Z Jiang, M Shrestha
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