Clinical validation of 18F-AZD4694, an amyloid-β–specific PET radioligand Z Cselényi, ME Jönhagen, A Forsberg, C Halldin, P Julin, M Schou, ... Journal of Nuclear Medicine 53 (3), 415-424, 2012 | 250 | 2012 |
PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brain M Schou, C Halldin, J Sóvágó, VW Pike, H Hall, B Gulyás, PD Mozley, ... Synapse 53 (2), 57-67, 2004 | 139 | 2004 |
Preclinical comparison of the blood–brain barrier permeability of osimertinib with other EGFR TKIs N Colclough, K Chen, P Johnström, N Strittmatter, Y Yan, GL Wrigley, ... Clinical Cancer Research 27 (1), 189-201, 2021 | 128 | 2021 |
New methodologies for the preparation of carbon-11 labeled radiopharmaceuticals K Dahl, C Halldin, M Schou Clinical and Translational Imaging 5, 275-289, 2017 | 96 | 2017 |
Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: a PET study in nonhuman primate brain using (S,S)-[18F]FMeNER-D2 N Seneca, B Gulyás, A Varrone, M Schou, A Airaksinen, J Tauscher, ... Psychopharmacology 188, 119-127, 2006 | 96 | 2006 |
Specific in vivo binding to the norepinephrine transporter demonstrated with the PET radioligand,(S, S)-[11C] MeNER M Schou, C Halldin, J Sóvágó, VW Pike, B Gulyás, PD Mozley, ... Nuclear medicine and biology 30 (7), 707-714, 2003 | 84 | 2003 |
Post-mortem human brain autoradiography of the norepinephrine transporter using (S, S)-[18F] FMeNER-D2 M Schou, C Halldin, VW Pike, PD Mozley, D Dobson, RB Innis, L Farde, ... European Neuropsychopharmacology 15 (5), 517-520, 2005 | 82 | 2005 |
Palladium‐Mediated [11C]Carbonylation at Atmospheric Pressure: A General Method Using Xantphos as Supporting Ligand K Dahl, M Schou, N Amini, C Halldin European Journal of Organic Chemistry 2013 (7), 1228-1231, 2013 | 75 | 2013 |
In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE‐PE2I, a new dopamine transporter PET radioligand A Varrone, C Steiger, M Schou, A Takano, SJ Finnema, D Guilloteau, ... Synapse 63 (10), 871-880, 2009 | 69 | 2009 |
Synthesis, radiolabeling and preliminary in vivo evaluation of [18F] FE-PE2I, a new probe for the dopamine transporter M Schou, C Steiger, A Varrone, D Guilloteau, C Halldin Bioorganic & Medicinal Chemistry Letters 19 (16), 4843-4845, 2009 | 65 | 2009 |
Late‐Stage Isotopic Carbon Labeling of Pharmaceutically Relevant Cyclic Ureas Directly from CO2 A Del Vecchio, F Caillé, A Chevalier, O Loreau, K Horkka, C Halldin, ... Angewandte Chemie 130 (31), 9892-9896, 2018 | 56 | 2018 |
Transition‐metal‐free carbon isotope exchange of phenyl acetic acids G Destro, K Horkka, O Loreau, DA Buisson, L Kingston, A Del Vecchio, ... Angewandte Chemie 132 (32), 13592-13597, 2020 | 48 | 2020 |
A PET study in healthy subjects of brain exposure of 11C-labelled osimertinib – A drug intended for treatment of brain metastases in non-small cell lung cancer A Varrone, K Varnäs, A Jucaite, Z Cselényi, P Johnström, M Schou, ... Journal of Cerebral Blood Flow & Metabolism 40 (4), 799-807, 2020 | 47 | 2020 |
Brain exposure of the ATM inhibitor AZD1390 in humans—a positron emission tomography study A Jucaite, P Stenkrona, Z Cselényi, S De Vita, N Buil-Bruna, K Varnäs, ... Neuro-oncology 23 (4), 687-696, 2021 | 42 | 2021 |
Large variation in brain exposure of reference CNS drugs: a PET study in nonhuman primates M Schou, K Varnäs, S Lundquist, R Nakao, N Amini, A Takano, ... International Journal of Neuropsychopharmacology 18 (10), pyv036, 2015 | 42 | 2015 |
[18 F] fluoro-benziodoxole: a no-carrier-added electrophilic fluorinating reagent. Rapid, simple radiosynthesis, purification and application for fluorine-18 labelling MAC González, P Nordeman, AB Gómez, DN Meyer, G Antoni, M Schou, ... Chemical communications 54 (34), 4286-4289, 2018 | 40 | 2018 |
Identification of positron emission tomography (PET) tracer candidates by prediction of the target-bound fraction in the brain M Fridén, M Wennerberg, M Antonsson, M Sandberg-Ställ, L Farde, ... EJNMMI research 4, 1-8, 2014 | 36 | 2014 |
Synthesis and evaluation of pyridylbenzofuran, pyridylbenzothiazole and pyridylbenzoxazole derivatives as 18F-PET imaging agents for β-amyloid plaques BM Swahn, J Sandell, D Pyring, M Bergh, F Jeppsson, A Juréus, ... Bioorganic & medicinal chemistry letters 22 (13), 4332-4337, 2012 | 34 | 2012 |
Radiolabeling of a high potency cannabinoid subtype‐1 receptor ligand, N‐(4‐fluoro‐benzyl)‐4‐(3‐(piperidin‐1‐yl)‐indole‐1‐sulfonyl)benzamide (PipISB), with … SR Donohue, C Halldin, M Schou, J Hong, L Phebus, E Chernet, ... Journal of Labelled Compounds and Radiopharmaceuticals: The Official Journal …, 2008 | 33 | 2008 |
Identification of PET radiometabolites by cytochrome P450, UHPLC/Q-ToF-MS and fast radio-LC: applied to the PET radioligands [11 C] flumazenil,[18 F] FE-PE2I, and [11 C] PBR28 N Amini, R Nakao, M Schou, C Halldin Analytical and bioanalytical chemistry 405, 1303-1310, 2013 | 31 | 2013 |