Neil S Holden
Neil S Holden
Verified email at - Homepage
Cited by
Cited by
Separating transrepression and transactivation: a distressing divorce for the glucocorticoid receptor?
R Newton, NS Holden
Molecular pharmacology 72 (4), 799-809, 2007
Inhibition of NF-κB-dependent transcription by MKP-1: transcriptional repression by glucocorticoids occurring via p38 MAPK
EM King, NS Holden, W Gong, CF Rider, R Newton
Journal of Biological Chemistry 284 (39), 26803-26815, 2009
Phorbol ester-stimulated NF-κB-dependent transcription: roles for isoforms of novel protein kinase C
NS Holden, PE Squires, M Kaur, R Bland, CE Jones, R Newton
Cellular signalling 20 (7), 1338-1348, 2008
Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IκB kinase inhibitors
R Newton, NS Holden, MC Catley, W Oyelusi, R Leigh, D Proud, ...
Journal of Pharmacology and Experimental Therapeutics 321 (2), 734-742, 2007
IL-1β-dependent activation of NF-κB mediates PGE2 release via the expression of cyclooxygenase-2 and microsomal prostaglandin E synthase
MC Catley, JE Chivers, LM Cambridge, N Holden, DM Slater, KJ Staples, ...
FEBS letters 547 (1-3), 75-79, 2003
Inhibitors of protein kinase C (PKC) prevent activated transcription: role of events downstream of NF-κB DNA binding
MC Catley, LM Cambridge, Y Nasuhara, K Ito, JE Chivers, A Beaton, ...
Journal of Biological Chemistry 279 (18), 18457-18466, 2004
β2-Adrenoceptor agonist-induced RGS2 expression is a genomic mechanism of bronchoprotection that is enhanced by glucocorticoids
NS Holden, MJ Bell, CF Rider, EM King, DD Gaunt, R Leigh, M Johnson, ...
Proceedings of the National Academy of Sciences 108 (49), 19713-19718, 2011
Corticosteroid‐induced gene expression in allergen‐challenged asthmatic subjects taking inhaled budesonide
MM Kelly, EM King, CF Rider, C Gwozd, NS Holden, J Eddleston, B Zuraw, ...
British journal of pharmacology 165 (6), 1737-1747, 2012
Inhibitors of p38 mitogen-activated protein kinase: potential as anti-inflammatory agents in asthma?
R Newton, N Holden
BioDrugs 17, 113-129, 2003
Principles and problems of the electrophoretic mobility shift assay
NS Holden, CE Tacon
Journal of pharmacological and toxicological methods 63 (1), 7-14, 2011
Effect of β2-adrenoceptor agonists and other cAMP-elevating agents on inflammatory gene expression in human ASM cells: a role for protein kinase A
M Kaur, NS Holden, SM Wilson, MB Sukkar, KF Chung, PJ Barnes, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 295 (3 …, 2008
Analysis of the dissociated steroid RU24858 does not exclude a role for inducible genes in the anti-inflammatory actions of glucocorticoids
JE Chivers, W Gong, EM King, J Seybold, JC Mak, LE Donnelly, ...
Molecular pharmacology 70 (6), 2084-2095, 2006
Inflammatory stimuli inhibit glucocorticoid-dependent transactivation in human pulmonary epithelial cells: rescue by long-acting β2-adrenoceptor agonists
CF Rider, EM King, NS Holden, MA Giembycz, R Newton
Journal of Pharmacology and Experimental Therapeutics 338 (3), 860-869, 2011
Efficacy of supervised maintenance exercise following pulmonary rehabilitation on health care use: a systematic review and meta-analysis
AR Jenkins, H Gowler, F Curtis, NS Holden, C Bridle, AW Jones
International journal of chronic obstructive pulmonary disease, 257-273, 2018
Human rhinovirus infection up-regulates MMP-9 production in airway epithelial cells via NF-κB
CE Tacon, S Wiehler, NS Holden, R Newton, D Proud, R Leigh
American journal of respiratory cell and molecular biology 43 (2), 201-209, 2010
ICAM‐1 expression is highly NF‐κB‐dependent in A549 cells: No role for ERK and p38 MAPK
NS Holden, MC Catley, LM Cambridge, PJ Barnes, R Newton
European journal of biochemistry 271 (4), 785-791, 2004
Regulation of tristetraprolin expression by interleukin-1β and dexamethasone in human pulmonary epithelial cells: roles for nuclear factor-κB and p38 mitogen-activated protein …
EM King, M Kaur, W Gong, CF Rider, NS Holden, R Newton
Journal of Pharmacology and Experimental Therapeutics 330 (2), 575-585, 2009
Validation of IKKβ as therapeutic target in airway inflammatory disease by adenoviral‐mediated delivery of dominant‐negative IKKβ to pulmonary epithelial cells
MC Catley, JE Chivers, NS Holden, PJ Barnes, R Newton
British journal of pharmacology 145 (1), 114-122, 2005
Induction of regulator of G-protein signaling 2 expression by long-acting β2-adrenoceptor agonists and glucocorticoids in human airway epithelial cells
NS Holden, T George, CF Rider, A Chandrasekhar, S Shah, M Kaur, ...
Journal of Pharmacology and Experimental Therapeutics 348 (1), 12-24, 2014
Glucocorticoids inhibit IL-1β-induced GM-CSF expression at multiple levels: roles for the ERK pathway and repression by MKP-1
R Newton, EM King, W Gong, CF Rider, KJ Staples, NS Holden, ...
Biochemical Journal 427 (1), 113-124, 2010
The system can't perform the operation now. Try again later.
Articles 1–20