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John Hulleman
John Hulleman
Associate Professor and Larson Endowed Chair for Macular Degeneration, University of Minnesota
Verified email at umn.edu - Homepage
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Cited by
Cited by
Year
Helical α-synuclein forms highly conductive ion channels
SD Zakharov, JD Hulleman, EA Dutseva, YN Antonenko, JC Rochet, ...
Biochemistry 46 (50), 14369-14379, 2007
1552007
Mechanisms of DJ‐1 neuroprotection in a cellular model of Parkinson’s disease
F Liu, JL Nguyen, JD Hulleman, L Li, JC Rochet
Journal of neurochemistry 105 (6), 2435-2453, 2008
1172008
Site-specific modification of Alzheimer's peptides by cholesterol oxidation products enhances aggregation energetics and neurotoxicity
K Usui, JD Hulleman, JF Paulsson, SJ Siegel, ET Powers, JW Kelly
Proceedings of the National Academy of Sciences 106 (44), 18563-18568, 2009
992009
Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain
CB Cooley, LM Ryno, L Plate, GJ Morgan, JD Hulleman, JW Kelly, ...
Proceedings of the National Academy of Sciences 111 (36), 13046-13051, 2014
932014
Destabilization of DJ-1 by familial substitution and oxidative modifications: implications for Parkinson's disease
JD Hulleman, H Mirzaei, E Guigard, KL Taylor, SS Ray, CM Kay, ...
Biochemistry 46 (19), 5776-5789, 2007
752007
ATF6 activation reduces the secretion and extracellular aggregation of destabilized variants of an amyloidogenic protein
JJ Chen, JC Genereux, S Qu, JD Hulleman, MD Shoulders, RL Wiseman
Chemistry & biology 21 (11), 1564-1574, 2014
692014
The systemic amyloid precursor transthyretin (TTR) behaves as a neuronal stress protein regulated by HSF1 in SH-SY5Y human neuroblastoma cells and APP23 Alzheimer's disease …
X Wang, F Cattaneo, L Ryno, J Hulleman, N Reixach, JN Buxbaum
Journal of Neuroscience 34 (21), 7253-7265, 2014
652014
A trimethoprim derivative impedes antibiotic resistance evolution
MS Manna, YT Tamer, I Gaszek, N Poulides, A Ahmed, X Wang, ...
Nature communications 12 (1), 2949, 2021
462021
Compromised mutant EFEMP1 secretion associated with macular dystrophy remedied by proteostasis network alteration
JD Hulleman, S Kaushal, WE Balch, JW Kelly
Molecular biology of the cell 22 (24), 4765-4775, 2011
362011
Malattia Leventinese/Doyne honeycomb retinal dystrophy: similarities to age-related macular degeneration and potential therapies
JD Hulleman
Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 153-158, 2016
312016
Protein-templated semiconductor nanoparticle chains
S Padalkar, JD Hulleman, SM Kim, JC Rochet, EA Stach, LA Stanciu
Nanotechnology 19 (27), 275602, 2008
312008
Effect of single amino acid substitution on oxidative modifications of the Parkinson’s disease-related protein, DJ-1
AG Madian, J Hindupur, JD Hulleman, N Diaz-Maldonado, VR Mishra, ...
Molecular & cellular proteomics 11 (2), 2012
282012
A High-Throughput Cell-Based Gaussia Luciferase Reporter Assay for Identifying Modulators of Fibulin-3 Secretion
JD Hulleman, SJ Brown, H Rosen, JW Kelly
Journal of biomolecular screening 18 (6), 647-658, 2013
262013
Trinucleotide repeat-targeting dCas9 as a therapeutic strategy for Fuchs’ endothelial corneal dystrophy
Z Rong, X Gong, JD Hulleman, DR Corey, VV Mootha
Translational Vision Science & Technology 9 (9), 47-47, 2020
242020
Genetic ablation of N-linked glycosylation reveals two key folding pathways for R345W fibulin-3, a secreted protein associated with retinal degeneration
JD Hulleman, JW Kelly
The FASEB Journal 29 (2), 565, 2015
242015
Translational attenuation differentially alters the fate of disease-associated fibulin proteins
JD Hulleman, WE Balch, JW Kelly
The FASEB Journal 26 (11), 4548, 2012
242012
A destabilizing domain allows for fast, noninvasive, conditional control of protein abundance in the mouse eye–implications for ocular gene therapy
S Datta, M Renwick, VQ Chau, F Zhang, ER Nettesheim, DM Lipinski, ...
Investigative ophthalmology & visual science 59 (12), 4909-4920, 2018
232018
An inducible form of Nrf2 confers enhanced protection against acute oxidative stresses in RPE cells
KT Vu, JD Hulleman
Experimental eye research 164, 31-36, 2017
222017
Delivery of antisense oligonucleotides to the cornea
VQ Chau, J Hu, X Gong, JD Hulleman, RL Ufret-Vincenty, F Rigo, ...
nucleic acid therapeutics 30 (4), 207-214, 2020
212020
Deducing the presence of proteins and proteoforms in quantitative proteomics
C Bamberger, S Martínez-Bartolomé, M Montgomery, S Pankow, ...
Nature communications 9 (1), 2320, 2018
212018
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