| The bone marrow microenvironment at single-cell resolution AN Tikhonova, I Dolgalev, H Hu, KK Sivaraj, E Hoxha, ... Nature 569 (7755), 222-228, 2019 | 729 | 2019 |
| Restoration of TET2 function blocks aberrant self-renewal and leukemia progression L Cimmino, I Dolgalev, Y Wang, A Yoshimi, GH Martin, J Wang, V Ng, ... Cell 170 (6), 1079-1095. e20, 2017 | 636 | 2017 |
| Extensive remodeling of the immune microenvironment in B cell acute lymphoblastic leukemia MT Witkowski, I Dolgalev, NA Evensen, C Ma, T Chambers, KG Roberts, ... Cancer cell 37 (6), 867-882. e12, 2020 | 129 | 2020 |
| Mechanisms of resistance to noncovalent Bruton’s tyrosine kinase inhibitors E Wang, X Mi, MC Thompson, S Montoya, RQ Notti, J Afaghani, ... New England Journal of Medicine 386 (8), 735-743, 2022 | 118 | 2022 |
| Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia GJ Liu, L Cimmino, JG Jude, Y Hu, MT Witkowski, MD McKenzie, ... Genes & development 28 (12), 1337-1350, 2014 | 108 | 2014 |
| Interconversion between tumorigenic and differentiated states in acute myeloid leukemia MD McKenzie, M Ghisi, EP Oxley, S Ngo, L Cimmino, C Esnault, R Liu, ... Cell stem cell 25 (2), 258-272. e9, 2019 | 79 | 2019 |
| Leukemia-on-a-chip: Dissecting the chemoresistance mechanisms in B cell acute lymphoblastic leukemia bone marrow niche C Ma, MT Witkowski, J Harris, I Dolgalev, S Sreeram, W Qian, J Tong, ... Science advances 6 (44), eaba5536, 2020 | 62 | 2020 |
| Physiological restraint of Bak by Bcl-xL is essential for cell survival EF Lee, S Grabow, S Chappaz, G Dewson, C Hockings, RM Kluck, ... Genes & development 30 (10), 1240-1250, 2016 | 54 | 2016 |
| An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia A Lasry, B Nadorp, M Fornerod, D Nicolet, H Wu, CJ Walker, Z Sun, ... Nature cancer 4 (1), 27-42, 2023 | 52 | 2023 |
| Surface antigen-guided CRISPR screens identify regulators of myeloid leukemia differentiation E Wang, H Zhou, B Nadorp, G Cayanan, X Chen, AH Yeaton, S Nomikou, ... Cell Stem Cell 28 (4), 718-731. e6, 2021 | 46 | 2021 |
| Immune-based therapies in acute leukemia MT Witkowski, A Lasry, WL Carroll, I Aifantis Trends in cancer 5 (10), 604-618, 2019 | 45 | 2019 |
| Valine tRNA levels and availability regulate complex I assembly in leukaemia P Thandapani, A Kloetgen, MT Witkowski, C Glytsou, AK Lee, E Wang, ... Nature 601 (7893), 428-433, 2022 | 44 | 2022 |
| Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia MT Witkowski, L Cimmino, Y Hu, T Trimarchi, H Tagoh, MD McKenzie, ... Leukemia 29 (6), 1301-1311, 2015 | 44 | 2015 |
| PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia HM McRae, AL Garnham, Y Hu, MT Witkowski, MA Corbett, MP Dixon, ... Blood, The Journal of the American Society of Hematology 133 (16), 1729-1741, 2019 | 39 | 2019 |
| Mapping and targeting of the leukemic microenvironment MT Witkowski, S Kousteni, I Aifantis Journal of Experimental Medicine 217 (2), 2020 | 36 | 2020 |
| Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome MT Witkowski, Y Hu, KG Roberts, JM Boer, MD McKenzie, GJ Liu, ... Journal of Experimental Medicine 214 (3), 773-791, 2017 | 35 | 2017 |
| NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia MT Witkowski, S Lee, E Wang, AK Lee, A Talbot, C Ma, N Tsopoulidis, ... Nature immunology 23 (10), 1424-1432, 2022 | 17 | 2022 |
| Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion E Battistello, KA Hixon, DE Comstock, CK Collings, X Chen, JR Hernaez, ... Molecular cell 83 (8), 1216-1236. e12, 2023 | 15 | 2023 |
| Computational model of CAR T-cell immunotherapy dissects and predicts leukemia patient responses at remission, resistance, and relapse L Liu, C Ma, Z Zhang, MT Witkowski, I Aifantis, S Ghassemi, W Chen Journal for ImmunoTherapy of Cancer 10 (12), 2022 | 9 | 2022 |
| Single-cell analysis of acute lymphoblastic and lineage-ambiguous leukemia: approaches and molecular insights I Iacobucci, MT Witkowski, CG Mullighan Blood 141 (4), 356-368, 2023 | 5 | 2023 |
