The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells LP Vu, BF Pickering, Y Cheng, S Zaccara, D Nguyen, G Minuesa, T Chou, ... Nature medicine 23 (11), 1369-1376, 2017 | 1023 | 2017 |
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90 K Moulick, JH Ahn, H Zong, A Rodina, L Cerchietti, EM Gomes DaGama, ... Nature chemical biology 7 (11), 818-826, 2011 | 298 | 2011 |
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation L Wang, A Gural, XJ Sun, X Zhao, F Perna, G Huang, MA Hatlen, L Vu, ... Science 333 (6043), 765-769, 2011 | 248 | 2011 |
m6A RNA methylation maintains hematopoietic stem cell identity and symmetric commitment Y Cheng, H Luo, F Izzo, BF Pickering, D Nguyen, R Myers, A Schurer, ... Cell reports 28 (7), 1703-1716. e6, 2019 | 137 | 2019 |
The Biology of m6A RNA Methylation in Normal and Malignant Hematopoiesis LP Vu, Y Cheng, MG Kharas Cancer discovery 9 (1), 25-33, 2019 | 131 | 2019 |
Musashi2 sustains the mixed-lineage leukemia–driven stem cell regulatory program SM Park, M Gönen, L Vu, G Minuesa, P Tivnan, TS Barlowe, J Taggart, ... The Journal of clinical investigation 125 (3), 1286-1298, 2015 | 110 | 2015 |
PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex LP Vu, F Perna, L Wang, F Voza, ME Figueroa, P Tempst, ... Cell reports 5 (6), 1625-1638, 2013 | 93 | 2013 |
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells LP Vu, C Prieto, EM Amin, S Chhangawala, A Krivtsov, MN Calvo-Vidal, ... Nature genetics 49 (6), 866-875, 2017 | 86 | 2017 |
Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias K Wang, M Sanchez-Martin, X Wang, KM Knapp, R Koche, L Vu, ... Leukemia 31 (1), 151-158, 2017 | 76 | 2017 |
CARM1 is essential for myeloid leukemogenesis but dispensable for normal hematopoiesis SM Greenblatt, N Man, PJ Hamard, T Asai, D Karl, C Martinez, D Bilbao, ... Cancer cell 33 (6), 1111-1127. e5, 2018 | 63 | 2018 |
Post-translational modifications of Runx1 regulate its activity in the cell L Wang, G Huang, X Zhao, MA Hatlen, L Vu, F Liu, SD Nimer Blood Cells, Molecules, and Diseases 43 (1), 30-34, 2009 | 44 | 2009 |
HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells DTT Nguyen, Y Lu, KL Chu, X Yang, SM Park, ZN Choo, CR Chin, ... Nature Communications 11 (1), 2026, 2020 | 41 | 2020 |
Histone-binding of DPF2 mediates its repressive role in myeloid differentiation FM Huber, SM Greenblatt, AM Davenport, C Martinez, Y Xu, LP Vu, ... Proceedings of the National Academy of Sciences 114 (23), 6016-6021, 2017 | 34 | 2017 |
MSI2 is required for maintaining activated myelodysplastic syndrome stem cells J Taggart, TC Ho, E Amin, H Xu, TS Barlowe, AR Perez, BH Durham, ... Nature communications 7 (1), 10739, 2016 | 34 | 2016 |
Histone-modifying enzymes: their role in the pathogenesis of acute leukemia and their therapeutic potential LP Vu, L Luciani, SD Nimer International journal of hematology 97, 198-209, 2013 | 22 | 2013 |
Transcriptional control of CBX5 by the RNA-binding proteins RBMX and RBMXL1 maintains chromatin state in myeloid leukemia C Prieto, DTT Nguyen, Z Liu, J Wheat, A Perez, S Gourkanti, T Chou, ... Nature cancer 2 (7), 741-757, 2021 | 16 | 2021 |
The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells F Perna, LP Vu, M Themeli, S Kriks, R Hoya-Arias, R Khanin, T Hricik, ... Stem cell reports 4 (4), 658-669, 2015 | 11 | 2015 |
Targeting the residual leukemia cells after chemotherapy LP Vu, MG Kharas Cancer Cell 34 (3), 353-355, 2018 | 6 | 2018 |
A target discovery pipeline identified ILT3 as a target for immunotherapy of multiple myeloma F Di Meo, A Iyer, K Akama, R Cheng, C Yu, A Cesarano, N Kurihara, ... Cell Reports Medicine 4 (7), 2023 | 3 | 2023 |
RNA modifications in hematological malignancies Z Jin, K MacPherson, Z Liu, LP Vu International Journal of Hematology 117 (6), 807-820, 2023 | 3 | 2023 |